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How to get fromGrimes to Chicagoby plane, bus (Greyhound), car, bus, or train

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There are 6 ways to get from Grimes to Chicago by plane, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Chicago O'Hare International Airport

    best
    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2h 51m
    $98–403

  2. Drive to Fort Dodge Municipal Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Drive from Grimes to Fort Dodge Municipal Airport (FOD)car car
    2. Fly from Fort Dodge Municipal Airport (FOD) to Chicago O'Hare International Airport (ORD)plane plane FOD - ORD
    3h 52m
    $51–266

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    7h 23m
    $85–136

  4. Drive 341.2 mi

    1. Drive from Grimes to Chicagocar car 341.2 mi
    5h 40m
    $63–90

  5. Fly Des Moines to Chicago Midway International Airport

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2h 31m
    $108–483

  6. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus Greyhound US0157S
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    8h 43m
    $115–211

Des Moines (DSM) to Chicago O'Hare International Airport (ORD) flights

Calendar106Weekly Planes
Duration1h 58mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Grimes to Chicago.ExpandLaunch map view
  • Distance: 332.6 mi
  • Duration: 2h 51m

What companies run services between Grimes, IA, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $50–95 and the journey takes 7h 5m.

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