There are 8 ways to get from Grenoble to Mainz by train, plane, train (TGV), bus, car, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Lyon–Saint Exupéry Airport, fly to Frankfurt
best- Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane LYS - FRA
5h 6m€126–344Bus via Frankfurt
cheapest- Take the bus from Grenoble to Lyonbus FlixBus S1777 / ...
- Take the bus from Lyon to Frankfurt Airportbus FlixBus N235 / ...
13h 25m€35–66Train via Paris
- Take the train from Grenoble to Paris Gare De Lyontrain Tgv
- Take the train from Paris Est to Mannheim Hbftrain Ice
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
9h 5m€123–502Drive 717.2 km
- Drive from Grenoble to Mainzcar 717.2 km
6h 33m€109–157Train to Geneva International Airport, fly to Frankfurt
- Take the train from Grenoble to Genevetrain
- Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane GVA - FRA
6h 23m€154–320Train to Lyon–Saint Exupéry Airport, fly to Strasbourg International Airport, train
- Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane LYS - SXB
- Take the train from Strasbourg to Mannheim Hbftrain
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain
7h 19m€156–380Train
- Take the train from Grenoble to Genevetrain Ter
- Take the train from Genève to Renens VDtrain Ic1 / ...
- Take the train from Renens VD to Basel SBBtrain
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 20 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
10h 12m€122–279Bus
- Take the bus from Grenoble - Oxford Bus Stop to Lyon - Perrache Bus Stationbus BlaBlaCar Bus
- Take the bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str.bus
13h 44m€91–124
Grenoble to Mainz by train and foot
Questions & Answers
The cheapest way to get from Grenoble to Mainz is to bus via Frankfurt which costs €35 - €70 and takes 13h 25m.
The fastest way to get from Grenoble to Mainz is to train and fly which takes 5h 6m and costs €120 - €350.
No, there is no direct bus from Grenoble to Mainz. However, there are services departing from Grenoble and arriving at Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus via Lyon and Frankfurt. The journey, including transfers, takes approximately 13h 25m.
No, there is no direct train from Grenoble to Mainz. However, there are services departing from Grenoble and arriving at Mainz, Römisches Theater via Paris Gare de Lyon, Paris Est and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 9h 5m.
The distance between Grenoble and Mainz is 688 km. The road distance is 717.2 km.
The best way to get from Grenoble to Mainz without a car is to train via Paris which takes 9h 5m and costs €120 - €500.
It takes approximately 5h 6m to get from Grenoble to Mainz, including transfers.
Grenoble to Mainz bus services, operated by FlixBus-eu, depart from Grenoble station.
Grenoble to Mainz train services, operated by TGV inOui, depart from Grenoble station.
The best way to get from Grenoble to Mainz is to train via Paris which takes 9h 5m and costs €120 - €500. Alternatively, you can bus via Frankfurt, which costs €35 - €70 and takes 13h 25m.
What companies run services between Grenoble, France and Mainz, Germany?
You can take a train from Grenoble to Mainz, Römisches Theater via Paris Gare de Lyon, Paris Gare Du Nord, Paris Est, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 9h 5m. Alternatively, you can take a bus from Grenoble to Ginsheim-Gustavsburg-Gustavsburg Am Alten Fährhaus via Lyon, Frankfurt Airport, and Frankfurt in around 13h 25m.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €85–300
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Munich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €95–300
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €70–310
Flights from Geneva International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €70–240
- Website
- swiss.com
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €70–310
Flights from Geneva International Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €70–310
- Website
- brusselsairlines.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 42m
- When
- Monday to Saturday
- Estimated price
- €65–220
Flights from Geneva International Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 25m
- When
- Monday to Saturday
- Estimated price
- €60–210
- Website
- airdolomiti.it
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Sunday
- Estimated price
- €85–280
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–270
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Strasbourg International Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €500–1,200
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Paris Charles de Gaulle
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €40–270
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- €19–20
- Website
- https://www.sncf-connect.com/en-en
Train from Grenoble to Paris Gare De Lyon
- Ave. Duration
- 3h 1m
- Frequency
- Every 4 hours
- Estimated price
- €60–150
- Website
- https://www.sncf-connect.com/en-en
Train from Paris Est to Mannheim Hbf
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- €45–280
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg to Mannheim Hbf
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- €30–65
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Grenoble to Paris Gare De Lyon
- Ave. Duration
- 2h 57m
- Frequency
- Once daily
- Estimated price
- €90–200
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €90–140
- Rail 1st Class
- €140–200
Train from Grenoble to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Paris Est to Mannheim Hbf
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- €60–140
- Website
- https://int.bahn.de/en
Train from Strasbourg to Mannheim Hbf
- Ave. Duration
- 1h 4m
- Frequency
- 4 times a day
- Estimated price
- €30–50
- Website
- https://int.bahn.de/en
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 14m
- Frequency
- Hourly
- Estimated price
- €27–65
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Genève to Renens VD
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €13–26
- Website
- https://www.sbb.ch/en
Train from Renens VD to Basel SBB
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €35–70
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 12m
- Frequency
- Once daily
- Estimated price
- €55–110
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €75–110
- 2nd Class
- €55–80
- Website
- global.flixbus.com
Bus from Grenoble to Lyon
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Schedules at
- global.flixbus.com
Bus from Lyon to Frankfurt Airport
- Ave. Duration
- 10h 5m
- Frequency
- Twice daily
- Schedules at
- global.flixbus.com
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Grenoble to Lyon
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €5–12
- Website
- https://www.flixbus.co.uk
Bus from Lyon to Frankfurt Airport
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Grenoble - Oxford Bus Stop to Lyon - Perrache Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €17–24
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +48 801 22 33 44
- bilety@sindbad.pl
- Website
- sindbad.pl
Bus from LYON, Lyon - Perrache - poziom górny A to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str.
- Ave. Duration
- 10h 10m
- Frequency
- Once a week
- Estimated price
- €65–85
- Website
- https://www.sindbad.pl/en/home
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
More Questions & Answers
Grenoble to Mainz bus services, operated by FlixBus-eu, arrive at Lyon station.
Grenoble to Mainz train services, operated by TGV inOui, arrive at Paris Gare De Lyon station.
Yes, the driving distance between Grenoble to Mainz is 717 km. It takes approximately 6h 33m to drive from Grenoble to Mainz.
Book your Grenoble to Mainz train tickets online with Omio.
There are 1132+ hotels available in Mainz.














































