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  • Deutsche Bahn
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There are 8 ways to get from Grenoble to Brussels by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train inOui TGV  •  6h 7m

  1. Take the train from Grenoble to Lyon Part Dieu
  2. Take the train from Lyon Part Dieu to Bruxelles Midi Tgv

$164 - $194

Cheapest option

Bus  •  13h 45m

  1. Take the bus from Grenoble - Bus station to Lyon Gare Perrache Ouibus / ...
  2. Take the bus from Lyon, Lyon Perrache to Brussels, Brussels-North station N769

$49 - $85

6 alternative options

Train Thalys  •  6h 8m

  1. Take the train from Grenoble to Chambery-Challes-E
  2. Take the train from Chambery to Brussel-Zuid/Midi Thalys

$227 - $294

Train, bus  •  14h 12m

  1. Take the train from Grenoble to Lyon Part Dieu
  2. Take the bus from Lyon to Brussels-North

$112 - $167

Drive  •  7h 56m

  1. Drive from Grenoble to Brussels 525.3 miles

$110 - $170

Train to Lyon, fly to Brussels  •  4h 46m

  1. Take the train from Grenoble to Lyon-St Exupery(TGV)
  2. Fly from Lyon (LYS) to Brussels (BRU) LYS - BRU

$66 - $253

Train to Geneva, fly to Brussels  •  6h 14m

  1. Take the train from Grenoble to Genève
  2. Fly from Geneva (GVA) to Brussels (BRU) GVA - BRU

$83 - $259

Train to Lyon, fly to Lille Lesquin, train  •  5h 57m

  1. Take the train from Grenoble to Lyon-St Exupery(TGV)
  2. Fly from Lyon (LYS) to Lille Lesquin (LIL) LYS - LIL
  3. Take the train from Lille Europe Eurostar to Bruxelles-Midi Eurostar

$122 - $382

Questions & Answers

The cheapest way to get from Grenoble to Brussels is to bus which costs 40€ - 75€ and takes 13h 45m.

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The quickest way to get from Grenoble to Brussels is to train and fly which costs 55€ - 220€ and takes 4h 46m.

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No, there is no direct bus from Grenoble station to Brussels station. However, there are services departing from Grenoble - Bus station and arriving at Brussels, Brussels-North station via Lyon, Lyon Perrache. The journey, including transfers, takes approximately 13h 45m.

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No, there is no direct train from Grenoble to Brussels. However, there are services departing from Grenoble and arriving at Bruxelles Midi via Lyon Part Dieu. The journey, including transfers, takes approximately 6h 7m.

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The distance between Grenoble and Brussels is 640 km. The road distance is 840.5 km.

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The best way to get from Grenoble to Brussels without a car is to train which takes 6h 7m and costs 140€ - 170€.

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It takes approximately 6h 7m to get from Grenoble to Brussels, including transfers.

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Grenoble to Brussels bus services, operated by Ouibus, arrive at Grenoble - Bus station.

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Grenoble to Brussels train services, operated by SNCF, depart from Grenoble station.

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The best way to get from Grenoble to Brussels is to train which takes 6h 7m and costs 140€ - 170€. Alternatively, you can bus, which costs 40€ - 75€ and takes 13h 45m.

Mode details

Map of how to get from Grenoble to Brussels.
Launch map view
  • Distance: 399.8 miles
  • Duration: 6h 7m

What companies run services between Grenoble, France and Brussels, Belgium?

You can take a train from Grenoble to Brussels via Lyon Part Dieu in around 6h 7m. Alternatively, you can take a bus from Grenoble to Brussels via Lyon Gare Perrache and Lyon, Lyon Perrache in around 13h 45m.

Airlines
Swiss
Website
swiss.com
Flights from Geneva to Brussels
Ave. Duration
1h 17m
When
Every day
Estimated price
$60 - $460
Flights from Geneva to Brussels via Zurich
Ave. Duration
3h 15m
When
Every day
Estimated price
$110 - $400
Air France
Website
airfrance.com
Flights from Lyon to Brussels
Ave. Duration
1h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $420
Flights from Lyon to Brussels via Amsterdam Schiphol
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$140 - $550
Flights from Lyon to Lille Lesquin
Ave. Duration
1h 15m
When
Every day
Estimated price
$100 - $450
Flights from Lyon to Lille Lesquin via Nantes
Ave. Duration
3h 15m
When
Monday to Friday
Estimated price
$100 - $450
Brussels Airlines
Website
brusselsairlines.com
Flights from Lyon to Brussels
Ave. Duration
1h 21m
When
Every day
Estimated price
$60 - $370
Flights from Geneva to Brussels
Ave. Duration
1h 17m
When
Every day
Estimated price
$60 - $460
Hop!
Website
hop.com
Flights from Lyon to Brussels
Ave. Duration
1h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lyon to Lille Lesquin
Ave. Duration
1h 15m
When
Every day
Estimated price
$100 - $450
Flights from Lyon to Lille Lesquin via Nantes
Ave. Duration
3h 15m
When
Monday to Friday
Estimated price
$100 - $450
Lufthansa
Website
lufthansa.com
Flights from Lyon to Brussels via Frankfurt
Ave. Duration
3h 35m
When
Every day
Estimated price
$160 - $600
Flights from Geneva to Brussels via Frankfurt
Ave. Duration
3h 17m
When
Every day
Estimated price
$150 - $650
Flights from Geneva to Brussels via Munich
Ave. Duration
3h 30m
When
Every day
Estimated price
$150 - $650
easyJet
Website
easyjet.com
Flights from Geneva to Brussels
Ave. Duration
1h 18m
When
Every day
Estimated price
$45 - $290
KLM
Website
klm.com
Flights from Lyon to Brussels via Amsterdam Schiphol
Ave. Duration
3h 20m
When
Monday to Saturday
Estimated price
$140 - $550
Train operators
SNCF

Loosely translated as the French National Railway Corporation, the SNCF is France’s state-owned railway company. It covers the country’s extensive rail network, as well as the TGV and Thalys, France’s two high-speed railway networks. With over 14,000 trains operating daily, it is a fast and efficient way of travelling around the country. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Grenoble to Lyon Part Dieu
Ave. Duration
1h 24m
Frequency
Every 30 minutes
Estimated price
$24 - $35
Website
en.oui.sncf
2nd Class
$24 - $35
1st Class
$30 - $50
Train from Grenoble to Chambery-Challes-E
Ave. Duration
46m
Frequency
Every 30 minutes
Estimated price
$16 - $24
Website
en.oui.sncf
2nd Class
$16 - $24
1st Class
$21 - $35
Train from Grenoble to Genève
Ave. Duration
2h 11m
Frequency
Every 4 hours
Estimated price
$30 - $55
Website
en.oui.sncf
inOui TGV
Phone
0033 892 353535
Website
en.oui.sncf
Train from Lyon Part Dieu to Bruxelles Midi
Ave. Duration
3h 43m
Frequency
4 times a day
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$190 - $280
Train from Grenoble to Lyon-St Exupery(TGV)
Ave. Duration
1h 4m
Frequency
Every 4 hours
Estimated price
$27 - $33
Website
en.oui.sncf
2nd Class
$27 - $33
1st Class
$46 - $50
Train from Lille Europe to Bruxelles Midi
Ave. Duration
35m
Frequency
Every 4 hours
Estimated price
$25 - $31
Website
en.oui.sncf
2nd Class
$25 - $31
1st Class
$44 - $47
Thalys
Phone
+32 70 66 77 88
Website
thalys.com
Train from Chambery to Brussel-Zuid/Midi
Ave. Duration
4h 22m
Frequency
Once a week
Estimated price
$210 - $270
Website
thalys.com
2nd Class
$210 - $270
1st Class
$280 - $390
Eurostar
Bus operators
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Grenoble - Bus station to Lyon Gare Perrache
Ave. Duration
1h 35m
Frequency
Every 4 hours
Estimated price
$4 - $6
Website
Ouibus
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Grenoble to Lyon, Lyon Perrache
Ave. Duration
1h 25m
Frequency
5 times a day
Estimated price
$5 - $10
Website
flixbus.co.uk
Bus from Lyon, Lyon Perrache to Brussels, Brussels-North station
Ave. Duration
11h 10m
Frequency
Twice daily
Estimated price
$45 - $75
Website
flixbus.co.uk
Isilines
Phone
0 892 89 12 00
Website
isilines.com
Bus from Grenoble to Lyon
Ave. Duration
1h 10m
Frequency
Twice daily
Estimated price
$5 - $10
Schedules at
isilines.com
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Lyon to Brussels-North
Ave. Duration
11h 30m
Frequency
Twice daily
Estimated price
$85 - $130
Schedules at
eurolines.fr

Want to know more about travelling around Belgium

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More Questions & Answers

The quickest flight from Lyon Airport to Brussels Airport is the direct flight which takes 1h 20m.

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Grenoble to Brussels bus services, operated by FlixBus, arrive at Brussels, Brussels-North station.

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Grenoble to Brussels train services, operated by inOui TGV, arrive at Bruxelles Midi station.

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Yes, the driving distance between Grenoble to Brussels is 841 km. It takes approximately 7h 56m to drive from Grenoble to Brussels.

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Air France, KLM, Hop! and two other airlines offer flights from Lyon Airport to Brussels Airport.

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Book your Grenoble to Brussels train tickets online with Rome2rio.

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There are 1037+ hotels available in Brussels. Prices start at $69 USD per night.

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