There are 8 ways to get from Grenoble to Brussels by train, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  6 h 7 min

  1. Take the train from Grenoble to Lyon Part Dieu
  2. Take the train from Lyon Part Dieu to Bruxelles Midi Tgv

$165 - $195

Cheapest option

Train, bus  •  13 h 13 min

  1. Take the train from Grenoble to Lyon Part Dieu
  2. Take the bus from Lyon, Lyon Perrache to Namur
  3. Take the train from Namur to Bru.-Centraal / Brux.-Central Ic / ...

$71 - $116

6 alternative options

Bus  •  14 h 5 min

  1. Take the bus from Grenoble - Bus station to Lyon - Perrache Bus station Ouibus / ...
  2. Take the bus from Lyon to Brussels-North

$89 - $140

Drive  •  7 h 56 min

  1. Drive from Grenoble to Brussels 525.3 miles

$110 - $170

Train to Lyon, fly to Brussels  •  4 h 38 min

  1. Take the train from Grenoble to Lyon-St Exupery(TGV)
  2. Fly from Lyon (LYS) to Brussels (BRU) LYS - BRU

$82 - $254

Train to Geneva, fly to Brussels  •  6 h 11 min

  1. Take the train from Grenoble to Genève
  2. Fly from Geneva (GVA) to Brussels (BRU) GVA - BRU

$98 - $261

Train to Lyon, fly to Lille Lesquin, train  •  5 h 50 min

  1. Take the train from Grenoble to Lyon-St Exupery(TGV)
  2. Fly from Lyon (LYS) to Lille Lesquin (LIL) LYS - LIL
  3. Take the train from Lille Europe Eurostar to Bruxelles-Midi Eurostar

$123 - $383

Train to Turin, fly to Brussels  •  8 h 11 min

  1. Take the train from Grenoble to Torino Porta Susa
  2. Fly from Turin (TRN) to Brussels (BRU) TRN - BRU

$137 - $367

Questions & Answers

The cheapest way to get from Grenoble to Brussels is to bus which costs 75€ - 120€ and takes 14 h 5 min.

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The quickest way to get from Grenoble to Brussels is to train and fly which costs 70€ - 220€ and takes 4 h 38 min.

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No, there is no direct bus from Grenoble station to Brussels. However, there are services departing from Grenoble - Bus station and arriving at Brussels-North via Lyon. The journey, including transfers, takes approximately 14 h 5 min.

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No, there is no direct train from Grenoble to Brussels. However, there are services departing from Grenoble and arriving at Bruxelles Midi via Lyon Part Dieu. The journey, including transfers, takes approximately 6 h 7 min.

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The distance between Grenoble and Brussels is 640 km. The road distance is 840.5 km.

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The best way to get from Grenoble to Brussels without a car is to train which takes 6 h 7 min and costs 140€ - 170€.

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It takes approximately 6 h 7 min to get from Grenoble to Brussels, including transfers.

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Grenoble to Brussels bus services, operated by Ouibus, arrive at Grenoble - Bus station.

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Grenoble to Brussels train services, operated by SNCF, depart from Grenoble station.

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The best way to get from Grenoble to Brussels is to train which takes 6 h 7 min and costs 140€ - 170€. Alternatively, you can bus, which costs 75€ - 120€ and takes 14 h 5 min.

Mode details

Map of how to get from Grenoble to Brussels.
Launch map view
  • Distance: 399.8 miles
  • Duration: 6 h 7 min

What companies run services between Grenoble, France and Brussels, Belgium?

You can take a train from Grenoble to Brussels via Lyon Part Dieu in around 6 h 7 min. Alternatively, you can take a bus from Grenoble to Brussels via Lyon - Perrache Bus station and Lyon in around 14 h 5 min.

Airlines
Lufthansa
Website
lufthansa.com
Flights from Lyon to Brussels via Frankfurt
Ave. Duration
3 h 10 min
When
Every day
Estimated price
$160 - $600
Flights from Lyon to Brussels via Munich
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$160 - $600
Flights from Geneva to Brussels via Frankfurt
Ave. Duration
3 h 18 min
When
Every day
Estimated price
$150 - $650
Flights from Geneva to Brussels via Munich
Ave. Duration
3 h 20 min
When
Every day
Estimated price
$150 - $650
Flights from Turin to Brussels via Frankfurt
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$190 - $650
Flights from Turin to Brussels via Munich
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$190 - $650
Brussels Airlines
Website
brusselsairlines.com
Flights from Lyon to Brussels
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$60 - $370
Flights from Geneva to Brussels
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$60 - $460
Flights from Turin to Brussels
Ave. Duration
1 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$110 - $850
Swiss
Website
swiss.com
Flights from Geneva to Brussels
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$60 - $460
Flights from Geneva to Brussels via Zurich
Ave. Duration
2 h 55 min
When
Every day
Estimated price
$110 - $400
Hop!
Website
hop.com
Flights from Lyon to Brussels
Ave. Duration
1 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$75 - $430
Flights from Lyon to Lille Lesquin
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$100 - $450
easyJet
Website
easyjet.com
Flights from Geneva to Brussels
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$45 - $290
KLM
Website
klm.com
Flights from Geneva to Brussels via Amsterdam
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$150 - $650
Train operators
SNCF

Loosely translated as the French National Railway Corporation, the SNCF is France’s state-owned railway company. It covers the country’s extensive rail network, as well as the TGV and Thalys, France’s two high-speed railway networks. With over 14,000 trains operating daily, it is a fast and efficient way of travelling around the country. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Grenoble to Lyon Part Dieu
Ave. Duration
1 h 24 min
Frequency
Every 30 minutes
Estimated price
$24 - $35
Website
en.oui.sncf
2nd Class
$24 - $35
1st Class
$30 - $55
Train from Grenoble to Genève
Ave. Duration
2 h 11 min
Frequency
Every 4 hours
Estimated price
$30 - $55
Website
en.oui.sncf
TGV
Phone
0033 892 353535
Website
sncf.com
Train from Lyon Part Dieu to Bruxelles Midi
Ave. Duration
3 h 43 min
Frequency
5 times a day
Estimated price
$140 - $160
Website
en.oui.sncf
2nd Class
$140 - $160
1st Class
$190 - $280
Train from Grenoble to Lyon-St Exupery(TGV)
Ave. Duration
1 h 4 min
Frequency
Every 4 hours
Estimated price
$27 - $33
Website
en.oui.sncf
2nd Class
$27 - $33
1st Class
$47 - $51
Train from Lille Europe to Bruxelles Midi
Ave. Duration
35 min
Frequency
Every 4 hours
Estimated price
$26 - $31
Website
en.oui.sncf
2nd Class
$26 - $31
1st Class
$45 - $48
Train from Grenoble to Torino Porta Susa
Ave. Duration
3 h 31 min
Frequency
Once daily
Estimated price
$50 - $60
Website
en.oui.sncf
2nd Class
$50 - $60
1st Class
$75 - $95
Belgian Railways (NMBS/SNCB)
Phone
+32 2 528 28 28
Website
b-rail.be
Train from Namur to Bru.-Centraal / Brux.-Central
Ave. Duration
1 h 6 min
Frequency
Every 30 minutes
Estimated price
$8 - $13
Website
belgianrail.be
Book at
eurail.com
2nd Class
$8 - $13
1st Class
$13 - $19
Eurostar
Rome2rio's guide to Eurostar
Contact Details
Website
eurostar.com
Train from Lille Europe Eurostar to Bruxelles-Midi Eurostar
Ave. Duration
35 min
Frequency
Every 4 hours
Estimated price
$30 - $60
Website
eurostar.com
Standard
$30 - $60
Premier
$67 - $69
Thalys
Website
thalys.com
Train from Lille Europe to Brussel-Zuid/Midi
Ave. Duration
36 min
Frequency
6 times a week
Estimated price
$30 - $55
Website
thalys.com
2nd Class
$30 - $55
1st Class
$55 - $70
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Lyon, Lyon Perrache to Namur
Ave. Duration
9 h
Frequency
6 times a week
Estimated price
$35 - $65
Website
flixbus.co.uk
Bus from Grenoble to Lyon, Lyon Perrache
Ave. Duration
1 h 30 min
Frequency
Every 4 hours
Estimated price
$6 - $10
Website
flixbus.co.uk
Ouibus

As the bus subsidiary of French railway SNCF, Ouibus offers comfortable, eco-friendly coaches serving 35 French cities and 11 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Grenoble - Bus station to Lyon - Perrache Bus station
Ave. Duration
1 h 35 min
Frequency
Every 4 hours
Estimated price
$4 - $6
Website
Ouibus
Isilines
Phone
0 892 89 12 00
Website
isilines.com
Bus from Grenoble to Lyon
Ave. Duration
1 h 10 min
Frequency
Once daily
Estimated price
$7 - $10
Schedules at
isilines.com
Eurolines FR
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Lyon to Brussels-North
Ave. Duration
11 h 30 min
Frequency
Twice daily
Estimated price
$85 - $130
Schedules at
eurolines.fr

Want to know more about travelling around Belgium

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More Questions & Answers

The quickest flight from Lyon Airport to Brussels Airport is the direct flight which takes 1 h 15 min.

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Grenoble to Brussels bus services, operated by Eurolines FR, arrive at Brussels-North station.

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Grenoble to Brussels train services, operated by TGV, arrive at Bruxelles Midi station.

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Yes, the driving distance between Grenoble to Brussels is 841 km. It takes approximately 7 h 56 min to drive from Grenoble to Brussels.

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Brussels Airlines, Hop! and Lufthansa offer flights from Lyon Airport to Brussels Airport.

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Book your Grenoble to Brussels train tickets online with Rome2rio.

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There are 954+ hotels available in Brussels. Prices start at $70 USD per night.

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