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How to get fromGreer to Des Moinesby plane, bus (Greyhound, Flixbus), bus, train, car or taxi

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There are 8 ways to get from Greer to Des Moines by plane, bus (Greyhound, Flixbus), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)plane plane GSP - DSM
    4h 37m
    $278–1,346

  2. Drive 955.4 mi

    cheapest
    1. Drive from Greer to Des Moinescar car 955.4 mi
    17h 26m
    $175–252

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus
    2. Take the bus from Grand Hyatt Atlanta in Buckhead to Omni Nashville Hotelbus bus
    3. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    29h 10m
    $390–694

  4. Bus, train via Indianapolis

    1. Take the bus from Servicios Zapata - Spartanburg to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Charlottesvilletrain train
    3. Take the train from Charlottesville to Indianapolistrain train
    4. Take the bus from Indianapolis to Chicago Bus Stationbus bus
    5. Take the bus from Chicago Bus Station to Des Moinesbus bus
    39h 50m
    $420–905

  5. Taxi to Asheville Regional Airport, fly

    1. Take the taxi from Greer to Asheville-Airport-AVLtaxi taxi
    2. Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)plane plane AVL - DSM
    5h 31m
    $314–1,083

  6. Drive to Columbia, fly

    1. Drive from Greer to Columbia-Airport-CAEcar car
    2. Fly from Columbia (CAE) to Des Moines (DSM)plane plane CAE - DSM
    6h 28m
    $446–2,249

  7. Bus, train

    1. Take the bus from Servicios Zapata - Spartanburg to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    42h 38m
    $506–1,120

  8. Bus, train #2

    1. Take the bus from Servicios Zapata - Spartanburg to Charlottebus bus
    2. Take the train from Charlotte Amtrak Station to Carytrain train
    3. Take the train from Cary to Chicago Union Stationtrain train
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    42h 46m
    $506–1,120

Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) flights

Calendar98Weekly Planes
Duration5h 28mAverage Duration
Ticket$245Cheapest Price
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Questions & Answers

What companies run services between Greer, SC, USA and Des Moines, IA, USA?

Delta, American Airlines, and United Airlines fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) hourly. Alternatively, you can take a vehicle from Greer to Des Moines via Taqueria Guadalajara - Greenville, Atlanta, Grand Hyatt Atlanta in Buckhead, Omni Nashville Hotel, Peabody Station Outbound, Fulton Station Outbound, Nashville Bus Station, and Chicago Bus Station in around 29h 10m.

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