There are 7 ways to get from Greer to Des Moines by plane, bus (Flixbus), bus, train, car, taxi, bus (Greyhound, Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Greenville–Spartanburg International Airport
best- Fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM)GSP - DSM
4h 50m$245–1,142Drive 955.4 mi
cheapest- Drive from Greer to Des Moines955.4 mi
17h 18m$175–252Bus via St. Louis
- Take the bus from Greenville, SC to AtlantaNyc
- Take the bus from Atlanta Bus Station to St Louis Bus Station
- Take the bus from St Louis to Burlington
- Take the bus from Burlington to Des Moines
24h 41m$229–449Bus, train
- Take the bus from Servicios Zapata - Spartanburg to Charlotte
- Take the train from Charlotte Amtrak Station to Cary
- Take the train from Cary to Chicago Union Station
- Take the bus from Chicago to Des Moines
41h 19m$264–698Taxi to Asheville Regional Airport, fly
- Take the taxi from Greer to Asheville Regional Airport (AVL)
- Fly from Asheville Regional Airport (AVL) to Des Moines (DSM)AVL - DSM
5h 34m$304–983Bus
- Take the bus from Greenville, SC to AtlantaNyc
- Take the bus from Grand Hyatt Atlanta in Buckhead to Omni Nashville Hotel
- Take the bus from Nashville Bus Station to Chicago Bus Station
- Take the bus from Chicago to Des Moines
26h 27m$350–595Bus #2
- Take the bus from Greenville, SC to AtlantaNyc
- Take the bus from Atlanta Bus Station to Chicago Train Station
- Take the bus from Chicago Bus Station to Des Moines
28h 38m$204–349
Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Greer to Des Moines is to drive which costs $170 - $260 and takes 17h 18m.
The fastest way to get from Greer to Des Moines is to fly which takes 4h 50m and costs $240 - $1,200.
The distance between Greer and Des Moines is 788 miles. The road distance is 961 miles.
The best way to get from Greer to Des Moines without a car is to bus via St. Louis which takes 24h 41m and costs $220 - $450.
It takes approximately 4h 50m to get from Greer to Des Moines, including transfers.
The best way to get from Greer to Des Moines is to fly which takes 4h 50m and costs $240 - $1,200. Alternatively, you can bus via St. Louis, which costs $220 - $450 and takes 24h 41m.
Des Moines is 1h behind Greer. It is currently 2:07 PM in Greer and 1:07 PM in Des Moines.
Yes, the driving distance between Greer to Des Moines is 961 miles. It takes approximately 17h 18m to drive from Greer to Des Moines.
There are 223+ hotels available in Des Moines.
What companies run services between Greer, SC, USA and Des Moines, IA, USA?
Delta, United Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Des Moines (DSM) every 2 hours. Alternatively, you can take a vehicle from Greer to Des Moines via Greenville, SC, Atlanta, Buford Hwy @ Mcelroy Rd, Doraville Station, Doraville Station, Garnett Station, Atlanta Bus Station, St Louis, and Burlington in around 24h 41m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Greenville–Spartanburg International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Greenville–Spartanburg International Airport to Des Moines via Reagan Washington
- Ave. Duration
- 5h 46m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $280–1,300
Flights from Greenville–Spartanburg International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 11m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–1,100
Flights from Asheville Regional Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $150–800
Flights from Asheville Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 59m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $150–800
- Website
- delta.com
Flights from Greenville–Spartanburg International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Greenville–Spartanburg International Airport to Des Moines via Detroit
- Ave. Duration
- 5h 37m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $240–1,200
Flights from Asheville Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $150–800
Flights from Asheville Regional Airport to Des Moines via Minneapolis
- Ave. Duration
- 8h 8m
- When
- Saturday
- Estimated price
- $180–850
- Website
- united.com
Flights from Greenville–Spartanburg International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Asheville Regional Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $150–800
- Website
- allegiantair.com
Flights from Greenville–Spartanburg International Airport to Des Moines via St. Petersburg
- Ave. Duration
- 6h 51m
- When
- Monday
- Estimated price
- $330–1,500
Flights from Asheville Regional Airport to Des Moines via St. Petersburg
- Ave. Duration
- 8h 3m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $240–1,100
Flights from Asheville Regional Airport to Des Moines via Orlando Sanford
- Ave. Duration
- 8h 55m
- When
- Wednesday
- Estimated price
- $230–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Charlotte Amtrak Station to Cary
- Ave. Duration
- 3h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- https://www.amtrak.com/home.html
Train from Cary to Chicago Union Station
- Ave. Duration
- 25h 21m
- Frequency
- Once daily
- Estimated price
- $95–310
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $95–260
- Coach Seat short notice purchase
- $130–310
- Business - advance purchase
- $190–750
- Business Class
- $280–700
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Greenville, SC to Atlanta
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $40–60
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to St Louis Bus Station
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $65–140
- Schedules at
- flixbus.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 3 times a day
- Estimated price
- $60–140
- Schedules at
- flixbus.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from St Louis to Burlington
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $50–127
- Website
- https://burlingtontrailways.com
- Saver Fares
- $50–75
- Flexible Fares
- $70–100
- Saver Fare
- $92
- Flex Fare
- $127
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Chicago to Des Moines
- Ave. Duration
- 7h 10m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–95
- Flexible Fares
- $90–130
- Saver Fare
- $55–110
- Flex Fare
- $75–160
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Servicios Zapata - Spartanburg to Charlotte
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–130
- Phone
- +1 844-866-5263
- inquiries@vonlane.com
- Website
- vonlane.com
Bus from Grand Hyatt Atlanta in Buckhead to Omni Nashville Hotel
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $130–150
- Website
- https://vonlane.com
- Adult
- $130–150
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- 4 times a day
- Estimated price
- $55–130
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Chicago Train Station
- Ave. Duration
- 15h 55m
- Frequency
- Twice daily
- Estimated price
- $85–160
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 7h 15m
- Frequency
- 3 times a day
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Ave. Duration
- 58 min
- Estimated price
- $130–170
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Corporate Taxi
- Phone
- +1 864-990-5556
- Website
- ataxi.co
Atlantis Taxi
- Phone
- +1 850-628-5670
- Website
- facebook.com
Checker Cab
- Phone
- +1 864-583-2721
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