There are 10 ways to get from Grand Rapids to Mayo Clinic by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Grand Rapids to Rochester  •  6 h 49 min

  1. Fly from Grand Rapids (GRR) to Rochester (RST) GRR - RST

$221 - $1,215

Cheapest option

Amtrak Thruway, bus  •  13 h 16 min

  1. Take the Amtrak Thruway from Grand Rapids, MI to Kalamazoo, MI
  2. Take the bus from Kalamazoo, Mi to Chicago, Il
  3. Take the bus from Chicago, Il to Milwaukee, Wi
  4. Take the bus from Milwaukee to Rochester, MN 966

$90 - $161

8 alternative options

Fly Grand Rapids to Minneapolis, bus  •  6 h 17 min

  1. Fly from Grand Rapids (GRR) to Minneapolis (MSP) GRR - MSP
  2. Take the bus from Minneapolis-St Paul Airport, MN to Rochester, MN

$166 - $1,139

Fly Grand Rapids to La Crosse, bus  •  8 h 53 min

  1. Fly from Grand Rapids (GRR) to La Crosse (LSE) GRR - LSE
  2. Take the bus from La Crosse, WI to Rochester, MN

$278 - $1,348

Bus to Lansing, fly to Minneapolis, bus  •  7 h 35 min

  1. Take the bus from Grand Rapids, Mi to Lansing, Mi
  2. Fly from Lansing (LAN) to Minneapolis (MSP) LAN - MSP
  3. Take the bus from Minneapolis-St Paul Airport, MN to Rochester, MN

$178 - $528

Train to Chicago O'Hare, fly to Rochester  •  8 h 34 min

  1. Take the train from Grand Rapids Amtrak to Chicago Union Station Amtrak
  2. Fly from Chicago O'Hare (ORD) to Rochester (RST) ORD - RST

$198 - $807

Amtrak Thruway to Kalamazoo, fly to Minneapolis, bus  •  6 h 59 min

  1. Take the Amtrak Thruway from Grand Rapids, MI to Kalamazoo, MI
  2. Fly from Kalamazoo (AZO) to Minneapolis (MSP) AZO - MSP
  3. Take the bus from Minneapolis-St Paul Airport, MN to Rochester, MN

$234 - $586

Train, bus  •  13 h

  1. Take the train from Grand Rapids Amtrak to Chicago Union Station Amtrak
  2. Take the train from Chicago Union Station Amtrak to Winona Amtrak
  3. Take the bus from Winona, MN to Rochester, MN

$124 - $266

Bus, Amtrak Thruway  •  16 h 33 min

  1. Take the bus from Grand Rapids, MI to Chicago Union Station
  2. Take the Amtrak Thruway from Chicago, IL to Madison, WI - Univ. of Wisconsin
  3. Take the bus from Madison to Rochester, MN 966

Drive  •  8 h 46 min

  1. Drive from Grand Rapids to Mayo Clinic 532.3 miles

$50 - $80

Questions & Answers

The cheapest way to get from Grand Rapids to Mayo Clinic is to drive which costs $50 - $80 and takes 8 h 46 min.

More details

The quickest way to get from Grand Rapids to Mayo Clinic is to fly and bus which costs $160 - $1,200 and takes 6 h 17 min.

More details

The distance between Grand Rapids and Mayo Clinic is 350 miles. The road distance is 532.3 miles.

Get driving directions

It takes approximately 6 h 49 min to get from Grand Rapids to Mayo Clinic, including transfers.

More details

No, there is no direct bus from Grand Rapids to Mayo Clinic. However, there are services departing from Grand Rapids, MI and arriving at Rochester, MN via Kalamazoo, Mi, Chicago, Il and Milwaukee. The journey, including transfers, takes approximately 13 h 16 min.

More details

What companies run services between Grand Rapids, MI, USA and Mayo Clinic, MN, USA?

United Airlines, American Airlines and Delta fly from Grand Rapids to Mayo Clinic hourly. Alternatively, you can take a bus from Grand Rapids to Mayo Clinic via Kalamazoo, MI, Kalamazoo, Mi, Chicago, Il, Milwaukee, Wi, Milwaukee, and Rochester, MN in around 13 h 16 min.

Airlines
Delta
Website
delta.com
Flights from Grand Rapids to Rochester via Minneapolis
Ave. Duration
5 h 34 min
When
Every day
Estimated price
$210 - $1,200
Flights from Grand Rapids to Rochester via Detroit, Minneapolis
Ave. Duration
6 h 16 min
When
Saturday
Estimated price
$230 - $1,200
Flights from Grand Rapids to Minneapolis
Ave. Duration
1 h 32 min
When
Every day
Estimated price
$290 - $2,100
Flights from Grand Rapids to La Crosse via Minneapolis
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$230 - $1,300
Flights from Grand Rapids to La Crosse via Detroit, Minneapolis
Ave. Duration
7 h 3 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,300
Flights from Lansing to Minneapolis
Ave. Duration
1 h 41 min
When
Every day
Estimated price
$290 - $1,100
Flights from Lansing to Minneapolis via Detroit
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$290 - $1,100
Flights from Kalamazoo to Minneapolis
Ave. Duration
1 h 44 min
When
Every day
Estimated price
$310 - $1,100
Flights from Kalamazoo to Minneapolis via Detroit
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$310 - $1,100
American Airlines
Website
aa.com
Flights from Grand Rapids to Rochester via Chicago O'Hare
Ave. Duration
3 h 42 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,200
Flights from Grand Rapids to Minneapolis via Chicago O'Hare
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$170 - $800
Flights from Grand Rapids to La Crosse via Chicago O'Hare
Ave. Duration
3 h 33 min
When
Every day
Estimated price
$230 - $1,200
Flights from Grand Rapids to La Crosse via Charlotte, Chicago O'Hare
Ave. Duration
7 h 12 min
When
Every day
Estimated price
$350 - $1,500
Flights from Lansing to Minneapolis via Chicago O'Hare
Ave. Duration
3 h 50 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $1,100
Flights from Chicago O'Hare to Rochester
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$260 - $750
Flights from Kalamazoo to Minneapolis via Chicago O'Hare
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$330 - $1,200
United Airlines
Website
united.com
Flights from Grand Rapids to Rochester via Chicago O'Hare
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$240 - $1,200
Flights from Grand Rapids to Rochester via Washington Dulles, Chicago O'Hare
Ave. Duration
7 h 21 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,500
Flights from Grand Rapids to Minneapolis via Chicago O'Hare
Ave. Duration
3 h 35 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $2,300
Flights from Lansing to Minneapolis via Chicago O'Hare
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$310 - $1,100
Flights from Chicago O'Hare to Rochester
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$150 - $750
Flights from Kalamazoo to Minneapolis via Chicago O'Hare
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$320 - $1,200
Southwest Airlines
Website
southwest.com
Flights from Grand Rapids to Minneapolis via Chicago Midway
Ave. Duration
3 h 31 min
When
Saturday and Sunday
Estimated price
$260 - $3,100
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Grand Rapids Amtrak to Chicago Union Station Amtrak
Ave. Duration
4 h 8 min
Frequency
Once daily
Estimated price
$35 - $95
Website
amtrak.com
Coach Seat
$35 - $60
Flexi Coach Seat
$65 - $100
Business Coach Seat
$65 - $95
Room
$190 - $270
Train from Chicago Union Station Amtrak to Winona Amtrak
Ave. Duration
5 h 26 min
Frequency
3 times a day
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$95 - $140
Business Coach Seat
$95 - $140
Room
$240 - $340
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Minneapolis-St Paul Airport, MN to Rochester, MN
Ave. Duration
1 h 20 min
Frequency
Every 3 hours
Estimated price
$22 - $35
Schedules at
jeffersonlines.com
Bus from Milwaukee to Rochester, MN
Ave. Duration
6 h 10 min
Frequency
Every 3 hours
Estimated price
$55 - $80
Schedules at
jeffersonlines.com
Bus from Madison to Rochester, MN
Ave. Duration
4 h 45 min
Frequency
Every 3 hours
Estimated price
$45 - $65
Schedules at
jeffersonlines.com
Go Carefree Shuttle
Website
gocarefreeshuttle.com
Bus from La Crosse, WI to Rochester, MN
Ave. Duration
1 h 50 min
Frequency
Every 4 hours
Estimated price
$44
Schedules at
gocarefreeshuttle.com
Bus from Winona, MN to Rochester, MN
Ave. Duration
1 h 20 min
Frequency
Every 4 hours
Estimated price
$35
Schedules at
gocarefreeshuttle.com
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Grand Rapids, Mi to Lansing, Mi
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$13 - $30
Website
greyhound.com
Economy
$13 - $19
Flexible
$23 - $30
Bus from Kalamazoo, Mi to Chicago, Il
Ave. Duration
2 h 30 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from Chicago, Il to Milwaukee, Wi
Ave. Duration
1 h 50 min
Frequency
Every 30 minutes
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Indian Trails
Phone
+1 800-292-3831
Website
indiantrails.com
Bus from Grand Rapids, MI to Lansing
Ave. Duration
1 h 10 min
Frequency
Once daily
Estimated price
$12 - $17
Schedules at
indiantrails.com
Book at
webstore.indiantrails.com
Bus from Grand Rapids, MI to Chicago Union Station
Ave. Duration
5 h 10 min
Frequency
Twice daily
Estimated price
$30 - $50
Schedules at
indiantrails.com
Book at
webstore.indiantrails.com
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Grand Rapids, MI to Kalamazoo, MI
Ave. Duration
57 min
Frequency
Every 4 hours
Website
amtrak.com
Bus from Chicago, IL to Madison, WI - Univ. of Wisconsin
Ave. Duration
4 h 30 min
Frequency
Every 4 hours
Website
amtrak.com

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