There are 5 ways to get from Genoa to Siena by bus, train (Trenitalia), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Genoa to Sienabus 516 / ...
4h€18–35Train (Trenitalia)
- Take the train from Genova Brignole to Pisa Centraletrain Fb / ...
- Take the train from Pisa Centrale to Empolitrain Re
- Take the train from Empoli to Sienatrain Re
4h 17m€19–59Drive 264.3 km
- Drive from Genoa to Sienacar 264.3 km
3h 20m€41–59Bus via Florence
- Take the bus from Genova Brignole to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
4h 25m€23–34Bus via Pisa
- Take the bus from Genoa Piazza della Vittoria to PISA - Via Pietrasantina Parcheggiobus Turin
- Take the bus from Pisa to Siena, Stazione FSbus
7h€25–33
Genoa to Siena by bus
Questions & Answers
The cheapest way to get from Genoa to Siena is to bus which costs €18 - €35 and takes 4h.
The fastest way to get from Genoa to Siena is to drive which takes 3h 20m and costs €40 - €60.
Yes, there is a direct bus departing from Genoa and arriving at Siena. Services depart twice daily, and operate every day. The journey takes approximately 4h.
No, there is no direct train from Genoa to Siena. However, there are services departing from Genova Brignole and arriving at Siena via Pisa Centrale and Empoli. The journey, including transfers, takes approximately 4h 17m.
The distance between Genoa and Siena is 293 km. The road distance is 264.3 km.
The best way to get from Genoa to Siena without a car is to bus which takes 4h and costs €18 - €35.
The bus from Genoa to Siena takes 4h including transfers and departs twice daily.
Genoa to Siena bus services, operated by FlixBus, depart from Genoa station.
Genoa to Siena train services, operated by Trenitalia Frecce, depart from Genova Brignole station.
The best way to get from Genoa to Siena is to bus which takes 4h and costs €18 - €35. Alternatively, you can train, which costs €19 - €60 and takes 4h 17m.
What companies run services between Genoa, Italy and Siena, Italy?
FlixBus operates a bus from Genoa to Siena twice daily. Tickets cost €18–35 and the journey takes 4h. Alternatively, you can take a train from Genova Brignole to Siena via Pisa Centrale and Empoli in around 4h 17m.
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Genova Brignole to Pisa Centrale
- Ave. Duration
- 1h 52m
- Frequency
- Every 4 hours
- Estimated price
- €22–45
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Genova Brignole to Pisa Centrale
- Ave. Duration
- 2h 34m
- Frequency
- Every 4 hours
- Estimated price
- €15–40
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Genova Brignole to Pisa Centrale
- Ave. Duration
- 3h 23m
- Frequency
- Once a week
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Genoa to Siena
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- €18–35
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €4–7
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0827 34 117
- info@gruppodimaio.it
- Website
- gruppodimaio.it
Bus from Genova Brignole to Florence Villa Constanza Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Twice a week
- Estimated price
- €19–27
- Schedules at
- gruppodimaio.it
- Phone
- 0966 57552
- info@lirosiautoservizi.com
- Website
- lirosiautoserviziorari.com
Bus from Genoa Piazza della Vittoria to PISA - Via Pietrasantina Parcheggio
- Ave. Duration
- 2h 20m
- Frequency
- 4 times a week
- Estimated price
- €9–11
- Schedules at
- lirosiautoserviziorari.com
- Phone
- +39 089 233 899
- salerno@autolineecurcio.it
- Website
- autolineecurcio.it
Bus from Pisa to Siena, Stazione FS
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- €15–22
- Website
- https://www.autolineecurcio.it/
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
More Questions & Answers
Genoa to Siena bus services, operated by FlixBus, arrive at Siena station.
Genoa to Siena train services, operated by Trenitalia Frecce, arrive at Pisa Centrale station.
Yes, the driving distance between Genoa to Siena is 264 km. It takes approximately 3h 20m to drive from Genoa to Siena.
Book your Genoa to Siena train tickets online with Omio.
Book your Genoa to Siena bus tickets online with Omio and FlixBus.
There are 2301+ hotels available in Siena.



























