There are 10 ways to get from Genoa to Karlsruhe by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Genova Brignole to Milano Centraletrain Ic
- Take the train from Milano Centrale to Karlsruhe Hbftrain Ec
10h 11m€93–197Bus
cheapest- Take the bus from Genoa to Karlsruhe central train stationbus FlixBus N177
10h 50m€40–75Drive 664.6 km
- Drive from Genoa to Karlsruhecar 664.6 km
6h 33m€103–149Fly Genoa Cristoforo Colombo Airport to Stuttgart Airport, train
- Fly from Genoa Cristoforo Colombo Airport (GOA) to Stuttgart Airport (STR)plane GOA - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
10h 4m€91–300Bus via Zurich
- Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Zürichbus BlaBlaCar Bus
- Take the bus from Zürich to Karlsruhe - Central Station South Sidebus BlaBlaCar Bus
12h 55m€60–85Train to Milan Linate Airport, fly to Stuttgart Airport, train
- Take the train from Genova Brignole to Paviatrain
- Fly from Milan Linate Airport (LIN) to Stuttgart Airport (STR)plane LIN - STR
- Take the train from Stuttgart Hbf to Karlsruhe Hbftrain
7h 6m€125–312Train to Milan Linate Airport, fly to Frankfurt, train
- Take the train from Genova Brignole to Paviatrain
- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
7h 8m€70–251Train to Turin Caselle Airport, fly to Frankfurt, train
- Take the train from Genova P.Za Principe to Torino Lingottotrain
- Fly from Turin Caselle Airport (TRN) to Frankfurt (FRA)plane TRN - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
7h 44m€131–413Train, train to Milano Malpensa Airport, fly to Frankfurt
- Take the train from Genova Brignole to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane MXP - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
8h 45m€100–318Train, train to Nice Côte D'Azur International Airport, fly to Strasbourg International Airport
- Take the train from Genova P.Za Principe to Ventimigliatrain
- Take the train from Ventimiglia to Saint-Laurent-du-Vartrain
- Fly from Nice Côte D'Azur International Airport (NCE) to Strasbourg International Airport (SXB)plane NCE - SXB
- Take the train from Strasbourg to Karlsruhe Hbftrain
8h 23m€60–286
Genoa to Karlsruhe by train (Trenitalia)
Questions & Answers
The cheapest way to get from Genoa to Karlsruhe is to bus which costs €40 - €75 and takes 10h 50m.
The fastest way to get from Genoa to Karlsruhe is to drive which takes 6h 33m and costs €100 - €150.
Yes, there is a direct bus departing from Genoa and arriving at Karlsruhe central train station station. Services depart once daily, and operate every day. The journey takes approximately 10h 50m.
No, there is no direct train from Genoa to Karlsruhe. However, there are services departing from Genova Brignole and arriving at Karlsruhe Hbf via Milano Centrale. The journey, including transfers, takes approximately 10h 11m.
The distance between Genoa and Karlsruhe is 735 km. The road distance is 664.6 km.
The best way to get from Genoa to Karlsruhe without a car is to train which takes 10h 11m and costs €90 - €200.
It takes approximately 10h 11m to get from Genoa to Karlsruhe, including transfers.
Genoa to Karlsruhe bus services, operated by FlixBus, depart from Genoa station.
Genoa to Karlsruhe train services, operated by Trenitalia Intercity, depart from Genova Brignole station.
The best way to get from Genoa to Karlsruhe is to train which takes 10h 11m and costs €90 - €200. Alternatively, you can bus, which costs €40 - €75 and takes 10h 50m.
What companies run services between Genoa, Italy and Karlsruhe, Germany?
You can take a train from Genova Brignole to Karlsruhe Hbf via Milano Centrale in around 10h 11m. Alternatively, FlixBus operates a bus from Genoa to Karlsruhe central train station once daily. Tickets cost €40–75 and the journey takes 10h 50m. BlaBlaCar Bus also services this route 3 times a week.
- Website
- lufthansa.com
Flights from Genoa Cristoforo Colombo Airport to Stuttgart Airport via Munich
- Ave. Duration
- 7h 43m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–470
Flights from Milan Linate Airport to Stuttgart Airport via Frankfurt
- Ave. Duration
- 3h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–250
Flights from Milan Linate Airport to Stuttgart Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €90–250
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–320
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €60–350
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €80–330
Flights from Turin Caselle Airport to Frankfurt via Munich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €80–370
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €60–270
Flights from Milano Malpensa Airport to Frankfurt via Munich
- Ave. Duration
- 3h 10m
- When
- Monday to Wednesday
- Estimated price
- €75–300
- Website
- airdolomiti.it
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–320
Flights from Turin Caselle Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €90–330
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €70–270
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–130
Flights from Nice Côte D'Azur International Airport to Strasbourg International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €30–180
- Website
- eurowings.com
Flights from Genoa Cristoforo Colombo Airport to Stuttgart Airport via Budapest
- Ave. Duration
- 7h 45m
- When
- Tuesday
- Estimated price
- €85–240
Flights from Milan Linate Airport to Stuttgart Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €90–210
- Website
- condor.com
Flights from Milano Malpensa Airport to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €50–130
- Website
- volotea.com
Flights from Nice Côte D'Azur International Airport to Strasbourg International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €30–180
- Website
- swiss.com
Flights from Milano Malpensa Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- €60–270
- Website
- klm.com
Flights from Genoa Cristoforo Colombo Airport to Stuttgart Airport via Amsterdam Schiphol
- Ave. Duration
- 8h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €75–420
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 2h 52m
- Frequency
- Every 4 hours
- Estimated price
- €20–50
- Website
- https://www.trenitalia.com/en.html
Train from Genova Brignole to Pavia
- Ave. Duration
- 1h 14m
- Frequency
- Every 4 hours
- Estimated price
- €10–24
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 56m
- Frequency
- 3 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €14–35
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 2h 1m
- Frequency
- 4 times a day
- Estimated price
- €12–19
- Website
- https://www.trenitalia.com/en.html
Train from Genova Brignole to Pavia
- Ave. Duration
- 1h 23m
- Frequency
- Every 4 hours
- Estimated price
- €7–11
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 56m
- Frequency
- Every 3 hours
- Estimated price
- €9–14
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 1h 37m
- Frequency
- Twice daily
- Estimated price
- €29–60
- Schedules at
- trenitalia.com
Train from Genova Brignole to Pavia
- Ave. Duration
- 1h 6m
- Frequency
- Twice daily
- Estimated price
- €15–29
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Torino Lingotto
- Ave. Duration
- 1h 31m
- Frequency
- Once daily
- Estimated price
- €22–45
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Karlsruhe Hbf
- Ave. Duration
- 6h 19m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €80–120
- 2nd Class
- €100–140
- Phone
- +49 711 400 534 44
- service@gabw-bahn.de
- Website
- go-ahead-bw.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–27
- Schedules at
- go-ahead-bw.de
- 2nd Class Ticket
- €14–18
- 1st Class Ticket
- €18–27
- Phone
- +49 711 400 534 44
- stuttgart@arverio.de
- Website
- arverio-by.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Schedules at
- arverio-by.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €27–31
- Website
- https://int.bahn.de/en
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €26–30
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 23 min
- Frequency
- Hourly
- Estimated price
- €25–28
- Website
- https://int.bahn.de/en
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 41 min
- Frequency
- Every 4 hours
- Estimated price
- €27–31
- Website
- https://int.bahn.de/en
- Phone
- +49 711 2092-7087
- Website
- regional.bahn.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Schedules at
- regional.bahn.de
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 51 min
- Frequency
- 4 times a week
- Estimated price
- €22–30
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 731 1550-0
- servicecenter@dbregiobus-rab.de
- Website
- meine-rab.de
Train from Stuttgart Hbf to Karlsruhe Hbf
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €11–15
- Schedules at
- meine-rab.de
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Genova Brignole to Pavia
- Ave. Duration
- 1h 33m
- Frequency
- Twice a week
- Estimated price
- €7–10
- Website
- https://www.trenord.it/en/
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- 4 times a day
- Estimated price
- €12–40
- Website
- https://www.ns.nl/en
- 2nd Class
- €12–19
- 1st Class
- €23–40
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 28 min
- Frequency
- Once daily
- Estimated price
- €11–35
- Website
- https://www.ns.nl/en
- 2nd Class
- €11–17
- 1st Class
- €19–35
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- €12–18
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Ventimiglia to Saint-Laurent-du-Var
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- €7–16
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €7–11
- Rail 1st Class
- €11–16
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 52 min
- Frequency
- 5 times a week
- Estimated price
- €13–29
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €13–20
- Rail 1st Class
- €20–29
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Karlsruhe Hbf
- Ave. Duration
- 52 min
- Frequency
- 5 times a day
- Estimated price
- €21–55
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- €21–28
- 1st Class
- €40–55
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Genoa to Karlsruhe central train station
- Ave. Duration
- 10h 50m
- Frequency
- Once daily
- Estimated price
- €40–75
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Genoa to Karlsruhe central train station
- Ave. Duration
- 12h 5m
- Frequency
- 3 times a week
- Estimated price
- €45–65
- Website
- https://www.blablacar.co.uk/bus
Bus from Genoa - Via Fanti d'Italia Bus Stop to Zürich
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a week
- Estimated price
- €30–45
- Website
- https://www.blablacar.co.uk/bus
Bus from Zürich to Karlsruhe - Central Station South Side
- Ave. Duration
- 5h 15m
- Frequency
- 3 times a week
- Estimated price
- €27–40
- Website
- https://www.blablacar.co.uk/bus
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More Questions & Answers
Genoa to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Genoa to Karlsruhe train services, operated by Trenitalia Intercity, arrive at Milano Centrale station.
Yes, the driving distance between Genoa to Karlsruhe is 665 km. It takes approximately 6h 33m to drive from Genoa to Karlsruhe.
Book your Genoa to Karlsruhe train tickets online with Omio.
Book your Genoa to Karlsruhe bus tickets online with Omio and FlixBus.
There are 860+ hotels available in Karlsruhe.




































































