There are 9 ways to get from Genoa to Issoire by bus, train (Trenitalia), car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Genoa to Turinbus 501 / ...
- Take the bus from Turin to Lyonbus 480 / ...
- Take the bus from Lyon to Clermont-Ferrandbus 706 / ...
11h 11m€54–96Train
- Take the train from Genova Brignole to Torino Lingottotrain
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain Ter
11h 20m€94–164Drive 644.4 km
- Drive from Genoa to Issoirecar 644.4 km
7h€104–150Train, train to Milan Linate Airport, fly to Clermont-Ferrand Auvergne Airport
- Take the train from Genova Brignole to Vogheratrain
- Take the train from Voghera to Milano Forlaninitrain
- Fly from Milan Linate Airport (LIN) to Clermont-Ferrand Auvergne Airport (CFE)plane LIN - CFE
9h 46m€219–690Train, bus
- Take the train from Genova Brignole to Torino Porta Nuovatrain
- Take the bus from Turin Corso Vittorio Emanuele II to Lyon Lyon Perrache Bus Stationbus
- Take the train from Lyon Perrache to Clermont Ferrandtrain Ter
12h 23m€74–141Train, train to Milano Malpensa Airport, fly to Clermont-Ferrand Auvergne Airport
- Take the train from Genova Brignole to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Clermont-Ferrand Auvergne Airport (CFE)plane MXP - CFE
10h 25m€136–652Train, train to Nice Côte D'Azur International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Genova P.Za Principe to Ventimigliatrain
- Take the train from Ventimiglia to Saint-Laurent-du-Vartrain
- Fly from Nice Côte D'Azur International Airport (NCE) to Lyon–Saint Exupéry Airport (LYS)plane NCE - LYS
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain
10h 43m€163–394Fly Genoa Cristoforo Colombo Airport to Lyon–Saint Exupéry Airport, train
- Fly from Genoa Cristoforo Colombo Airport (GOA) to Lyon–Saint Exupéry Airport (LYS)plane GOA - LYS
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain
11h 9m€153–393Train, train to Milano Malpensa Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Genova Brignole to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Lyon–Saint Exupéry Airport (LYS)plane MXP - LYS
- Take the train from Lyon Part Dieu to Clermont Ferrandtrain
11h€136–321
Genoa to Issoire by bus
Comparing Your Travel Options
The cheapest way to get from Genoa to Issoire is to bus which costs €50 - €100 and takes 11h 11m.
The fastest way to get from Genoa to Issoire is to drive which takes 7h and costs €100 - €150.
No, there is no direct bus from Genoa to Issoire. However, there are services departing from Genoa and arriving at Issoire via Turin, Lyon, Maison de la Culture and Clermont Ferrand. The journey, including transfers, takes approximately 11h 11m.
No, there is no direct train from Genoa to Issoire. However, there are services departing from Genova Brignole and arriving at Issoire via Torino Lingotto, Torino Porta Susa, Lyon Part Dieu and Clermont Ferrand. The journey, including transfers, takes approximately 11h 20m.
The distance between Genoa and Issoire is 674 km. The road distance is 644.4 km.
The best way to get from Genoa to Issoire without a car is to bus which takes 11h 11m and costs €50 - €100.
It takes approximately 11h 11m to get from Genoa to Issoire, including transfers.
Genoa to Issoire bus services, operated by FlixBus, depart from Genoa station.
Genoa to Issoire train services, operated by Trenitalia, depart from Genova Brignole station.
The best way to get from Genoa to Issoire is to bus which takes 11h 11m and costs €50 - €100. Alternatively, you can train, which costs €90 - €170 and takes 11h 20m.
What companies run services between Genoa, Italy and Issoire, Auvergne-Rhône-Alpes, France?
You can take a bus from Genoa to Issoire via Turin, Lyon, Clermont-Ferrand, Maison de la Culture, Gare SNCF, and Clermont Ferrand in around 11h 11m. Alternatively, you can take a train from Genova Brignole to Issoire via Torino Lingotto, Torino Porta Susa, Lyon Part Dieu, and Clermont Ferrand in around 11h 20m.
- Website
- airfrance.com
Flights from Milan Linate Airport to Clermont-Ferrand Auvergne Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- €150–850
Flights from Milano Malpensa Airport to Clermont-Ferrand Auvergne Airport via Paris Charles de Gaulle
- Ave. Duration
- 4h 8m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- €110–750
Flights from Nice Côte D'Azur International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €40–290
Flights from Nice Côte D'Azur International Airport to Lyon–Saint Exupéry Airport via Bastia
- Ave. Duration
- 2h 40m
- When
- Monday and Saturday
- Estimated price
- €150–550
- Website
- easyjet.com
Flights from Nice Côte D'Azur International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 5m
- When
- Monday
- Estimated price
- €70–260
Flights from Genoa Cristoforo Colombo Airport to Lyon–Saint Exupéry Airport via Rome
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- €140–340
- Website
- lufthansa.com
Flights from Genoa Cristoforo Colombo Airport to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 5h 5m
- When
- Monday to Saturday
- Estimated price
- €120–440
Flights from Genoa Cristoforo Colombo Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 4h 40m
- When
- Sunday
- Estimated price
- €100–310
- Website
- twinjet.fr
Flights from Milano Malpensa Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h
- When
- Monday to Friday
- Estimated price
- €480–1,200
- Website
- aircorsica.com
Flights from Nice Côte D'Azur International Airport to Lyon–Saint Exupéry Airport via Bastia
- Ave. Duration
- 2h 40m
- When
- Monday and Saturday
- Estimated price
- €150–550
- Website
- airbus.com
Flights from Genoa Cristoforo Colombo Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 4h 40m
- When
- Sunday
- Estimated price
- €100–310
- Website
- volotea.com
Flights from Genoa Cristoforo Colombo Airport to Lyon–Saint Exupéry Airport via Olbia
- Ave. Duration
- 6h
- When
- Friday
- Estimated price
- €60–330
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Genova Brignole to Torino Lingotto
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- €18–26
- Website
- Trenitalia
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 3h 52m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Genova Brignole to Voghera
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Voghera to Milano Forlanini
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- Trenitalia
Train from Genova Brignole to Torino Porta Nuova
- Ave. Duration
- 2h 14m
- Frequency
- Hourly
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 2h 3m
- Frequency
- Every 3 hours
- Estimated price
- €17–24
- Website
- Trenitalia
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 3h 2m
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Trenitalia
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 2h 3m
- Frequency
- Every 3 hours
- Estimated price
- €17–24
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Genova Brignole to Torino Lingotto
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a day
- Estimated price
- €21–40
- Website
- Trenitalia Frecce
Train from Genova Brignole to Torino Porta Nuova
- Ave. Duration
- 1h 52m
- Frequency
- 3 times a day
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 1h 38m
- Frequency
- 3 times a day
- Estimated price
- €19–35
- Website
- Trenitalia Frecce
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 1h 38m
- Frequency
- 3 times a day
- Estimated price
- €19–35
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Genova Brignole to Torino Lingotto
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Genova Brignole to Voghera
- Ave. Duration
- 57 min
- Frequency
- Every 2 hours
- Estimated price
- €8–16
- Website
- Trenitalia Intercity
Train from Genova Brignole to Torino Porta Nuova
- Ave. Duration
- 2h 13m
- Frequency
- 4 times a day
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- €15–28
- Website
- Trenitalia Intercity
Train from Genova P.Za Principe to Ventimiglia
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €15–28
- Website
- Trenitalia Intercity
Train from Genova Brignole to Milano Centrale
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- €15–28
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Oui.SNCF
Train from Lyon Perrache to Clermont Ferrand
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Clermont Ferrand
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- €35–65
- Website
- Oui.SNCF
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- Trenord
Train from Genova Brignole to Voghera
- Ave. Duration
- 1h 17m
- Frequency
- 4 times a week
- Estimated price
- €6–8
- Website
- Trenord
Train from Voghera to Milano Forlanini
- Ave. Duration
- 49 min
- Frequency
- Every 4 hours
- Estimated price
- €5–7
- Website
- Trenord
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +33 4 13 94 30 50
- Website
- ZOU!
Train from Ventimiglia to Saint-Laurent-du-Var
- Ave. Duration
- 1h 9m
- Frequency
- Every 15 minutes
- Schedules at
- ZOU!
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Ventimiglia to Saint-Laurent-du-Var
- Ave. Duration
- 1h 10m
- Frequency
- Hourly
- Estimated price
- €11–15
- Website
- Zou! Lignes Express Régionales
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Genoa to Turin
- Ave. Duration
- 2h 15m
- Frequency
- Every 2 hours
- Estimated price
- €14–22
- Website
- Flixbus
Bus from Turin to Lyon
- Ave. Duration
- 4h 10m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Flixbus
Bus from Lyon to Clermont-Ferrand
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Turin to Lyon
- Ave. Duration
- 5h 20m
- Frequency
- Every 3 hours
- Estimated price
- €21–40
- Website
- BlaBlaCar Bus
Bus from Lyon to Clermont-Ferrand
- Ave. Duration
- 2h 44m
- Frequency
- Hourly
- Estimated price
- €11–20
- Website
- BlaBlaCar Bus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Turin Corso Vittorio Emanuele II to Lyon Lyon Perrache Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- €16–28
- Website
- Itabus S.p.A.
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Booking & Getting There
Genoa to Issoire bus services, operated by FlixBus, arrive at Turin station.
Genoa to Issoire train services, operated by Trenitalia, arrive at Torino Lingotto station.
Yes, the driving distance between Genoa to Issoire is 644 km. It takes approximately 7h to drive from Genoa to Issoire.
Book your Genoa to Issoire train tickets online with Omio.
There are 613+ hotels available in Issoire.

































