From Genoa bus to Florence. 2hrs 58min 18€. From Genova Brignole train to Pisa Centrale then train to Firenze S.M.N.. 3hrs 08min 29€. From Genova bus to Firenze. 4hrs 00min 27€. From Gênes rideshare to Florence. 3hrs 06min 12€. From Genoa drive to Florence. 2hrs 30min 45€. From Genova Piazza Principe train to Genoa airport, fly to Florence airport, then bus to Florence. 4hrs 22min 101€.