There are 5 ways to get from Gateway Arch to Lexington by bus (Greyhound), car, plane, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from St Louis Bus Station to Indianapolis Union StationGreyhound US0421
- Take the bus from Indianapolis Union Station to Lexington Bus StopGreyhound US0120
9h 52m$96–187Drive 338.2 mi
cheapest- Drive from Gateway Arch to Lexington338.2 mi
5h 42m$62–90Fly to Louisville International Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)STL - SDF
- Drive from Louisville International Airport (SDF) to Lexington
6h 14m$346–574Bus via Champaign
- Take the bus from St Louis Bus Station to Champaign Intermodal Trans Ctr
- Take the bus from Champaign to Indianapolis Union Station
- Take the bus from Indianapolis Union Station to Lexington Bus Stop
12h 53m$109–210Fly to Blue Grass Airport
- Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)STL - LEX
8h 11m$204–1,104
Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Gateway Arch to Lexington is to drive which costs $60 - $90 and takes 5h 42m.
The fastest way to get from Gateway Arch to Lexington is to drive which takes 5h 42m and costs $60 - $90.
The distance between Gateway Arch and Lexington is 450 miles. The road distance is 340.2 miles.
The best way to get from Gateway Arch to Lexington without a car is to bus which takes 9h 52m and costs $95 - $190.
It takes approximately 9h 52m to get from Gateway Arch to Lexington, including transfers.
The best way to get from Gateway Arch to Lexington is to bus which takes 9h 52m and costs $95 - $190. Alternatively, you can fly, which costs $200 - $1,100 and takes 8h 11m.
Yes, the driving distance between Gateway Arch to Lexington is 340 miles. It takes approximately 5h 42m to drive from Gateway Arch to Lexington.
There are 136+ hotels available in Lexington.
What companies run services between Gateway Arch, MO, USA and Lexington, KY, USA?
You can take a vehicle from Gateway Arch to Lexington via St Louis Bus Station, Indianapolis Union Station, and Lexington Bus Stop in around 9h 52m. Alternatively, Delta, United Airlines, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX) hourly.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 5h 7m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $160–850
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 8m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $250–1,300
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $330–1,600
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 6h 22m
- When
- Monday, Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- $330–1,600
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $150–800
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $140–750
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 36m
- When
- Tuesday
- Estimated price
- $220–1,200
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 6m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $100–650
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $110–700
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $29–45
- Schedules at
- flixbus.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Champaign to Indianapolis Union Station
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://burlingtontrailways.com
- Saver Fares
- $35–50
- Flexible Fares
- $45–70
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