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How to get fromGainesville to San Diegoby plane, bus (Flixbus), bus, train, car or bus (Flixbus, Greyhound)

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There are 7 ways to get from Gainesville to San Diego by plane, bus (Flixbus), bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gainesville Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to San Diego International Airport (SAN)planeGNV - SAN
    8h 37m
    $192–802

  2. Bus via Ciudad Juárez

    1. Take the bus from Circle K - Gainesville, FL to Houstonbus
    2. Take the bus from Houston to El Pasobus
    3. Take the bus from El Paso to 2474 E Florence Ave - Huntington Parkbus
    4. Take the bus from Huntington Park to San Diegobus
    46h 4m
    $415–754

  3. Bus, train

    1. Take the bus from Circle K - Gainesville, FL to Houstonbus
    2. Take the train from Houston to Los Angelestrain
    3. Take the train from Los Angeles to San Diegotrain
    2d 9h
    $377–1,038

  4. Drive 2,312.3 mi

    1. Drive from Gainesville to San Diegocar2,312.3 mi
    36h 10m
    $422–610

  5. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus
    2. Fly from Jacksonville (JAX) to San Diego International Airport (SAN)planeJAX - SAN
    9h 12m
    $447–925

  6. Bus to Orlando, fly

    1. Take the bus from Gainesville to Orlando RedCoach Stationbus
    2. Fly from Orlando (MCO) to San Diego International Airport (SAN)planeMCO - SAN
    8h 55m
    $277–912

  7. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus
    4. Take the bus from Los Angeles Union Station to San Diegobus
    2d 12h
    $251–564

Gainesville to San Diego by bus

Calendar11Weekly Buses
Duration2d 12hAverage Duration
Ticket$251Cheapest Price
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Questions & Answers

What companies run services between Gainesville, FL, USA and San Diego, CA, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a vehicle from Gainesville to San Diego via Circle K - Gainesville, FL, Houston, El Paso, and Huntington Park in around 46h 4m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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