There are 6 ways to get from Gainesville to Myrtle Beach by plane, bus (Flixbus, Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Gainesville Regional Airport
best- Fly from Gainesville Regional Airport (GNV) to Myrtle Beach (MYR)plane GNV - MYR
4h 42m$66–344Bus
cheapest- Take the bus from Gainesville to Jacksonvillebus
- Take the bus from Jacksonville to Florence Bus Stationbus
- Take the bus from Florence to Myrtle Beach, SCbus
10h 5m$64–211Drive 395.4 mi
- Drive from Gainesville to Myrtle Beachcar 395.4 mi
7h 33m$73–105Bus to Orlando, fly
- Take the bus from Gainesville to Orlando RedCoach Stationbus
- Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
5h 4m$115–428Bus to Jacksonville, fly
- Take the bus from Gainesville to Jacksonvillebus
- Fly from Jacksonville (JAX) to Myrtle Beach (MYR)plane JAX - MYR
7h 37m$267–837Bus, train
- Take the bus from Gainesville to Jacksonvillebus
- Take the train from Jacksonville to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
11h$88–128
Gainesville to Myrtle Beach by bus
Questions & Answers
The cheapest way to get from Gainesville to Myrtle Beach is to drive which costs $70 - $110 and takes 7h 33m.
The fastest way to get from Gainesville to Myrtle Beach is to fly which takes 4h 42m and costs $65 - $350.
No, there is no direct bus from Gainesville to Myrtle Beach. However, there are services departing from Gainesville and arriving at Myrtle Beach, SC via Jacksonville and Florence. The journey, including transfers, takes approximately 10h 5m.
The distance between Gainesville and Myrtle Beach is 349 miles. The road distance is 397.7 miles.
The best way to get from Gainesville to Myrtle Beach without a car is to bus which takes 10h 5m and costs $60 - $220.
It takes approximately 4h 42m to get from Gainesville to Myrtle Beach, including transfers.
Gainesville to Myrtle Beach bus services, operated by Flixbus USA, depart from Gainesville station.
The best way to get from Gainesville to Myrtle Beach is to fly which takes 4h 42m and costs $65 - $350. Alternatively, you can bus, which costs $60 - $220 and takes 10h 5m.
Gainesville to Myrtle Beach bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Gainesville to Myrtle Beach is 398 miles. It takes approximately 7h 33m to drive from Gainesville to Myrtle Beach.
What companies run services between Gainesville, FL, USA and Myrtle Beach, SC, USA?
Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Gainesville to Myrtle Beach, SC via Jacksonville, Florence Bus Station, and Florence in around 10h 5m.
- Website
- aa.com
Flights from Gainesville Regional Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $55–330
Flights from Gainesville Regional Airport to Myrtle Beach via Miami, Charlotte
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $85–430
Flights from Orlando to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $50–290
Flights from Jacksonville to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $70–440
- Website
- delta.com
Flights from Gainesville Regional Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $60–350
Flights from Orlando to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 44m
- When
- Monday, Thursday, and Friday
- Estimated price
- $55–300
Flights from Jacksonville to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $75–460
- Website
- southwest.com
Flights from Jacksonville to Myrtle Beach via Baltimore
- Ave. Duration
- 5h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–600
Flights from Jacksonville to Myrtle Beach via Nashville
- Ave. Duration
- 5h 42m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Website
- spirit.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 28m
- When
- Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $80–250
- Website
- flybreeze.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Charleston Amtrak Station
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- $60–90
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $15–22
- Schedules at
- flixbus.com
Bus from Jacksonville to Florence Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $35–95
- Schedules at
- flixbus.com
- Adult
- $35–95
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–17
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–14
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Gainesville to Orlando RedCoach Station
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
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