There are 8 ways to get from Gainesville to Murrells Inlet by plane, bus, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Gainesville Regional Airport
best- Fly from Gainesville Regional Airport (GNV) to Myrtle Beach (MYR)plane GNV - MYR
5h$96–362Drive 382.2 mi
cheapest- Drive from Gainesville to Murrells Inletcar 382.2 mi
7h 14m$70–101Bus, train, drive
- Take the bus from Gainesville to Jacksonvillebus
- Take the train from Jacksonville to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
10h 7m$118–248Bus, train
- Take the bus from Gainesville to Jacksonvillebus
- Take the train from Jacksonville to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
11h 11m$141–275Bus to Orlando, fly
- Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus
- Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
5h 21m$161–428Bus to Jacksonville, fly
- Take the bus from Gainesville to Jacksonvillebus
- Fly from Jacksonville (JAX) to Myrtle Beach (MYR)plane JAX - MYR
7h 40m$322–921Bus to Tampa, fly
- Take the bus from Gainesville to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
6h 37m$138–348Bus
- Take the bus from Gainesville to Jacksonvillebus
- Take the bus from Jacksonville to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
14h 11m$118–208
Gainesville Regional Airport (GNV) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Gainesville to Murrells Inlet is to drive which costs $70 - $110 and takes 7h 14m.
The fastest way to get from Gainesville to Murrells Inlet is to fly which takes 5h and costs $95 - $370.
No, there is no direct bus from Gainesville to Murrells Inlet station. However, there are services departing from Gainesville and arriving at Myrtle Beach Bus Station via Jacksonville and Camden. The journey, including transfers, takes approximately 14h 11m.
The distance between Gainesville and Murrells Inlet is 359 miles. The road distance is 384.5 miles.
The best way to get from Gainesville to Murrells Inlet without a car is to bus and train which takes 11h 11m and costs $140 - $280.
It takes approximately 5h to get from Gainesville to Murrells Inlet, including transfers.
Gainesville to Murrells Inlet bus services, operated by Flixbus USA, depart from Gainesville station.
The best way to get from Gainesville to Murrells Inlet is to fly which takes 5h and costs $95 - $370. Alternatively, you can bus, which costs $110 - $210 and takes 14h 11m.
Gainesville to Murrells Inlet bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Gainesville to Murrells Inlet is 384 miles. It takes approximately 7h 14m to drive from Gainesville to Murrells Inlet.
What companies run services between Gainesville, FL, USA and Murrells Inlet, SC, USA?
Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Gainesville to Murrells Inlet via Jacksonville, Camden, and Myrtle Beach Bus Station in around 14h 11m.
- Website
- aa.com
Flights from Gainesville Regional Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $55–310
Flights from Orlando to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $55–300
Flights from Jacksonville to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $60–340
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $65–350
- Website
- delta.com
Flights from Gainesville Regional Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $60–320
Flights from Orlando to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 2m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–310
Flights from Jacksonville to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $65–360
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $70–360
- Website
- southwest.com
Flights from Jacksonville to Myrtle Beach via Baltimore
- Ave. Duration
- 5h 15m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $95–460
Flights from Jacksonville to Myrtle Beach via Nashville
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $90–440
- Website
- flybreeze.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–280
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 41m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–260
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Kingstree Station
- Ave. Duration
- 5h 14m
- Frequency
- Once daily
- Estimated price
- $95–210
- Website
- Amtrak
Train from Jacksonville to Charleston Amtrak Station
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- $75–170
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Gainesville to Tampa Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 4 times a day
- Estimated price
- $14–29
- Website
- Greyhound
Bus from Jacksonville to Camden
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $50–100
- Website
- Greyhound
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $17–35
- Website
- Greyhound
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FL
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $29–60
- Website
- RedCoach
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 3085+ hotels available in Murrells Inlet.










