There are 7 ways to get from Gainesville to Murrells Inlet by plane, bus, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Gainesville Regional Airport
best- Fly from Gainesville Regional Airport (GNV) to Myrtle Beach (MYR)GNV - MYR
5h 11m$102–392Bus, train, drive
cheapest- Take the bus from Gainesville to Jacksonville
- Take the train from Jacksonville to Kingstree Station
- Drive from Kingstree Station to Murrells Inlet
10h 7m$63–162Bus
- Take the bus from Gainesville to Jacksonville
- Take the bus from Jacksonville to Florence Bus Station
- Take the bus from Florence to Myrtle Beach, SC
10h 26m$112–267Drive 382.1 mi
- Drive from Gainesville to Murrells Inlet382.1 mi
7h 11m$70–101Bus to Orlando, fly
- Take the bus from Gainesville to Orlando RedCoach Station
- Fly from Orlando (MCO) to Myrtle Beach (MYR)MCO - MYR
5h 11m$127–352Bus to Jacksonville, fly
- Take the bus from Gainesville to Jacksonville
- Fly from Jacksonville (JAX) to Myrtle Beach (MYR)JAX - MYR
7h 33m$297–625Bus, train
- Take the bus from Gainesville to Jacksonville
- Take the train from Jacksonville to Charleston Amtrak Station
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Station
11h 21m$143–225
Gainesville Regional Airport (GNV) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Gainesville to Murrells Inlet is to drive which costs $65 - $110 and takes 7h 11m.
The fastest way to get from Gainesville to Murrells Inlet is to bus and fly which takes 5h 11m and costs $120 - $360.
The distance between Gainesville and Murrells Inlet is 359 miles. The road distance is 384.4 miles.
The best way to get from Gainesville to Murrells Inlet without a car is to bus which takes 10h 26m and costs $110 - $270.
It takes approximately 5h 11m to get from Gainesville to Murrells Inlet, including transfers.
The best way to get from Gainesville to Murrells Inlet is to fly which takes 5h 11m and costs $100 - $400. Alternatively, you can bus, which costs $110 - $270 and takes 10h 26m.
Yes, the driving distance between Gainesville to Murrells Inlet is 384 miles. It takes approximately 7h 11m to drive from Gainesville to Murrells Inlet.
There are 2793+ hotels available in Murrells Inlet.
What companies run services between Gainesville, FL, USA and Murrells Inlet, SC, USA?
Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Gainesville to Murrells Inlet via Jacksonville, Florence Bus Station, Florence, and Myrtle Beach, SC in around 10h 26m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Gainesville Regional Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $60–340
Flights from Gainesville Regional Airport to Myrtle Beach via Miami, Charlotte
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $90–440
Flights from Jacksonville to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $75–420
- Website
- delta.com
Flights from Gainesville Regional Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $65–350
Flights from Jacksonville to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $80–450
- Website
- southwest.com
Flights from Jacksonville to Myrtle Beach via Baltimore
- Ave. Duration
- 4h 20m
- When
- Sunday
- Estimated price
- $110–600
Flights from Jacksonville to Myrtle Beach via Nashville
- Ave. Duration
- 6h 7m
- When
- Friday and Sunday
- Estimated price
- $110–550
- Website
- spirit.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 21m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $70–230
- Website
- flybreeze.com
Flights from Orlando to Myrtle Beach
- Ave. Duration
- 1h 35m
- When
- Thursday and Sunday
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Kingstree Station
- Ave. Duration
- 5h 14m
- Frequency
- Once daily
- Estimated price
- $35–120
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $35–80
- Coach Seat short notice purchase
- $35–120
- Business - advance purchase
- $50–240
- Business Class
- $85–290
Train from Jacksonville to Charleston Amtrak Station
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- $70–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–22
- Schedules at
- flixbus.com
Bus from Jacksonville to Florence Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $35–95
- Schedules at
- flixbus.com
- Adult
- $35–95
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $16–19
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Gainesville to Orlando RedCoach Station
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $14–60
- Website
- https://www.redcoachusa.com
- Web
- $14–60
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