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How to get fromGainesville to Iowaby plane, bus (Flixbus), bus, train, car or bus (Greyhound)

Find Transport to Iowa

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There are 10 ways to get from Gainesville to Iowa by plane, bus (Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Des Moines

    best
    1. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)planeGNV - DSM
    5h 57m
    $178–872

  2. Fly Gainesville Regional Airport to Quad City International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Quad City International Airport (MLI)planeGNV - MLI
    8h 3m
    $84–424

  3. Bus

    1. Take the bus from Gainesville to Atlanta - Civic Center MARTA Stationbus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis to Burlingtonbus
    4. Take the bus from Burlington to Des Moinesbus
    26h 49m
    $191–486

  4. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus
    2. Take the train from Jacksonville to Chicago Union Stationtrain
    3. Take the bus from Chicago to Des Moinesbus
    46h 56m
    $303–885

  5. Drive 1,211.8 mi

    1. Drive from Gainesville to Des Moinescar1,211.8 mi
    21h 2m
    $222–320

  6. Fly Gainesville Regional Airport to Omaha

    1. Fly from Gainesville Regional Airport (GNV) to Omaha (OMA)planeGNV - OMA
    6h 21m
    $176–832

  7. Fly Gainesville Regional Airport to The Eastern Iowa Airport

    1. Fly from Gainesville Regional Airport (GNV) to The Eastern Iowa Airport (CID)planeGNV - CID
    7h 58m
    $108–472

  8. Drive to Orlando Sanford, fly to Des Moines

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)planeSFB - DSM
    5h 37m
    $207–900

  9. Bus via Gainesville

    1. Take the bus from Gainesville to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
    3. Take the bus from St Louis to Burlingtonbus
    4. Take the bus from Burlington to Des Moinesbus
    27h 25m
    $197–465

  10. Bus #2 (Greyhound)

    1. Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to Chicago Train Stationbus
    3. Take the bus from Chicago Bus Station to Des Moinesbus
    33h 29m
    $184–448

Gainesville to Iowa by bus and subway

Calendar7Weekly Services
Duration26h 49mAverage Duration
Ticket$191Cheapest Price
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Questions & Answers

What companies run services between Gainesville, FL, USA and Iowa, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Gainesville to Des Moines via Atlanta - Civic Center MARTA Station, Civic Center Station, Garnett Station, Atlanta Bus Station, St Louis, and Burlington in around 26h 49m.

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