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How to get fromGainesville to Iowaby plane, bus, train, car or bus (Flixbus, Greyhound)

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There are 9 ways to get from Gainesville to Iowa by plane, bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Des Moines

    best
    1. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)plane plane GNV - DSM
    7h 19m
    $104–462

  2. Fly Gainesville Regional Airport to Quad City International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Quad City International Airport (MLI)plane plane GNV - MLI
    7h 11m
    $84–424

  3. Bus, train via Atlanta

    1. Take the bus from Gainesville to Atlanta - Civic Center MARTA Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Warrensburg Amtrak Stationtrain train
    4. Take the bus from Warrensburg Chamber Of Commerce to Kansas City Bus Stationbus bus
    5. Take the bus from Kansas City to Des Moinesbus bus
    28h 22m
    $175–478

  4. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    46h 25m
    $422–928

  5. Drive 1,211.8 mi

    1. Drive from Gainesville to Des Moinescar car 1,211.8 mi
    21h 13m
    $222–320

  6. Fly Gainesville Regional Airport to Omaha

    1. Fly from Gainesville Regional Airport (GNV) to Omaha (OMA)plane plane GNV - OMA
    6h 6m
    $256–1,232

  7. Drive to Orlando Sanford, fly to Des Moines

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    5h 41m
    $127–500

  8. Fly Gainesville Regional Airport to The Eastern Iowa Airport, bus

    1. Fly from Gainesville Regional Airport (GNV) to The Eastern Iowa Airport (CID)plane plane GNV - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    9h 42m

  9. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    29h 9m
    $187–397

Gainesville Regional Airport (GNV) to Des Moines (DSM) flights

Calendar41Weekly Planes
Duration7h 14mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

What companies run services between Gainesville, FL, USA and Iowa, USA?

American Airlines and Delta fly from Gainesville Regional Airport (GNV) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Gainesville to Des Moines via Atlanta Bus Station, Chicago Bus Station, and Des Moines in around 29h 9m.

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