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How to get fromGainesville to Iowaby plane, bus, train, car, bus (Flixbus, Greyhound), or bus (Greyhound)

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There are 10 ways to get from Gainesville to Iowa by plane, bus, train, car, bus (Flixbus, Greyhound), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Des Moines

    best
    1. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)plane plane GNV - DSM
    6h 22m
    $178–772

  2. Fly Gainesville Regional Airport to Quad City International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Quad City International Airport (MLI)plane plane GNV - MLI
    7h 4m
    $94–434

  3. Bus, train via Atlanta

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Des Moinesbus bus
    29h 11m
    $279–522

  4. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    46h 52m

  5. Drive 1,211.8 mi

    1. Drive from Gainesville to Des Moinescar car 1,211.8 mi
    21h 14m
    $222–320

  6. Fly Gainesville Regional Airport to Omaha

    1. Fly from Gainesville Regional Airport (GNV) to Omaha (OMA)plane plane GNV - OMA
    6h 13m
    $156–632

  7. Fly Gainesville Regional Airport to The Eastern Iowa Airport

    1. Fly from Gainesville Regional Airport (GNV) to The Eastern Iowa Airport (CID)plane plane GNV - CID
    9h 4m
    $96–452

  8. Drive to Orlando Sanford, fly to Des Moines

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    5h 31m
    $207–850

  9. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Des Moinesbus bus
    29h 36m

  10. Bus via Indianapolis

    1. Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    32h 29m
    $214–422

Gainesville to Iowa by bus, train, and foot

Calendar14Weekly Services
Duration29h 11mAverage Duration
Ticket$279Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Iowa.ExpandLaunch map view
  • Distance: 1,047.8 mi
  • Duration: 6h 22m

What companies run services between Gainesville, FL, USA and Iowa, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Gainesville to Des Moines via Atlanta Bus Station and Chicago in around 29h 36m.

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