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How to get fromGainesville to Houstonby plane, bus (Flixbus, Greyhound), car, or bus

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There are 8 ways to get from Gainesville to Houston by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to William P. Hobby Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to William P. Hobby Airport (HOU)plane plane GNV - HOU
    6h 42m
    $184–854

  2. Bus to Jacksonville, fly to George Bush Intercontinental Airport

    cheapest
    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to George Bush Intercontinental Airport (IAH)plane plane JAX - IAH
    7h 29m
    $113–573

  3. Bus

    1. Take the bus from Gainesville to Tallahasseebus bus FlixBus 2410
    2. Take the bus from Tallahassee to Houston Bus Stationbus bus Greyhound US0799
    19h 59m
    $134–248

  4. Drive 854.6 mi

    1. Drive from Gainesville to Houstoncar car 854.6 mi
    14h 1m
    $156–226

  5. Bus to Jacksonville, fly to William P. Hobby Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to William P. Hobby Airport (HOU)plane plane JAX - HOU
    7h 5m
    $193–971

  6. Bus to Orlando, fly to William P. Hobby Airport

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to William P. Hobby Airport (HOU)plane plane MCO - HOU
    6h 37m
    $503–1,056

  7. Bus to Orlando, fly to George Bush Intercontinental Airport

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to George Bush Intercontinental Airport (IAH)plane plane MCO - IAH
    7h 3m
    $133–268

  8. Bus to Tampa, fly to William P. Hobby Airport

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to University of South Florida - 3801 USF Holly Drbus bus
    2. Fly from Tampa (TPA) to William P. Hobby Airport (HOU)plane plane TPA - HOU
    8h 56m
    $308–763

Gainesville to Houston by bus and tram

Calendar5Weekly Services
Duration19h 59mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Houston.ExpandLaunch map view
  • Distance: 794.4 mi
  • Duration: 6h 42m

What companies run services between Gainesville, FL, USA and Houston, TX, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to William P. Hobby Airport (HOU) every 4 hours. Alternatively, you can take a bus from Gainesville to Central Station Capitol WB via Tallahassee, Houston Bus Station, and Magnolia Park Transit Center WB in around 19h 59m.

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