There are 10 ways to get from Gainesville to Chicago, IL by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Gainesville Regional Airport to Chicago O'Hare International Airport
best- Fly from Gainesville Regional Airport (GNV) to Chicago O'Hare International Airport (ORD)plane GNV - ORD
6h 45m$64–336Bus
- Take the bus from Gainesville to Atlanta - Civic Center MARTA Stationbus Orlando
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus FlixBus 2512 / ...
20h 54m$110–309Bus, train
- Take the bus from Gainesville to Jacksonvillebus FlixBus 2431
- Take the train from Jacksonville to Chicago Union Stationtrain Floridian
38h 46m$217–725Drive 1,002.7 mi
- Drive from Gainesville to Chicago, ILcar 1,002.7 mi
17h 51m$183–265Fly Gainesville Regional Airport to Chicago Midway International Airport
- Fly from Gainesville Regional Airport (GNV) to Chicago Midway International Airport (MDW)plane GNV - MDW
6h 35m$88–476Bus to Jacksonville, fly to Chicago Midway International Airport
- Take the bus from Gainesville to Jacksonvillebus
- Fly from Jacksonville (JAX) to Chicago Midway International Airport (MDW)plane JAX - MDW
7h 21m$129–680Bus to Jacksonville, fly to Chicago O'Hare International Airport
- Take the bus from Gainesville to Jacksonvillebus
- Fly from Jacksonville (JAX) to Chicago O'Hare International Airport (ORD)plane JAX - ORD
7h 45m$99–460Bus to Orlando, fly to Chicago Midway International Airport
- Take the bus from Gainesville to Orlando RedCoach Stationbus
- Fly from Orlando (MCO) to Chicago Midway International Airport (MDW)plane MCO - MDW
7h 17m$102–550Bus via Gainesville
- Take the bus from Gainesville to Atlanta Bus Stationbus FlixBus N2415 / ...
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus FlixBus 2512 / ...
21h 30m$127–241Bus via Gainesville Bus Stop (Greyhound)
- Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus Greyhound US0630
- Take the bus from Atlanta Bus Station to Chicago Train Stationbus Greyhound US0100
25h 51m$126–312
Gainesville to Chicago, IL by bus and subway
Questions & Answers
The cheapest way to get from Gainesville to Chicago, IL is to bus via Gainesville which costs $120 - $250 and takes 21h 30m.
The fastest way to get from Gainesville to Chicago, IL is to fly which takes 6h 35m and costs $85 - $480.
No, there is no direct bus from Gainesville to Chicago, IL station. However, there are services departing from Gainesville and arriving at Chicago Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 21h 30m.
The distance between Gainesville and Chicago, IL is 935 miles. The road distance is 1008.5 miles.
The best way to get from Gainesville to Chicago, IL without a car is to bus which takes 20h 54m and costs $110 - $310.
It takes approximately 6h 45m to get from Gainesville to Chicago, IL, including transfers.
Gainesville to Chicago, IL bus services, operated by Flixbus USA, depart from Gainesville station.
The best way to get from Gainesville to Chicago, IL is to fly which takes 6h 45m and costs $60 - $340. Alternatively, you can bus, which costs $110 - $310 and takes 20h 54m.
Gainesville to Chicago, IL bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Chicago, IL is 1h behind Gainesville. It is currently 8:58 AM in Gainesville and 7:58 AM in Chicago, IL.
What companies run services between Gainesville, FL, USA and Chicago, IL, USA?
Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Chicago O'Hare International Airport (ORD) every 3 hours. Alternatively, you can take a bus from Gainesville to Chicago Bus Station via Atlanta - Civic Center MARTA Station, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 20h 54m.
- Website
- delta.com
Flights from Gainesville Regional Airport to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $60–330
Flights from Gainesville Regional Airport to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $85–470
Flights from Jacksonville to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $110–650
Flights from Jacksonville to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $80–430
Flights from Orlando to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $75–410
- Website
- southwest.com
Flights from Gainesville Regional Airport to Chicago Midway International Airport via Charlotte
- Ave. Duration
- 6h 52m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–490
Flights from Jacksonville to Chicago Midway International Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Jacksonville to Chicago Midway International Airport via Nashville
- Ave. Duration
- 4h 5m
- When
- Monday to Friday
- Estimated price
- $110–650
Flights from Orlando to Chicago Midway International Airport
- Ave. Duration
- 2h 54m
- When
- Every day
- Estimated price
- $75–410
Flights from Orlando to Chicago Midway International Airport via Indianapolis
- Ave. Duration
- 4h 45m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $75–410
Flights from Orlando to Chicago Midway International Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- $75–410
- Website
- aa.com
Flights from Gainesville Regional Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $65–340
Flights from Gainesville Regional Airport to Chicago O'Hare International Airport via Miami
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $85–410
Flights from Gainesville Regional Airport to Chicago O'Hare International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $95–440
Flights from Jacksonville to Chicago O'Hare International Airport
- Ave. Duration
- 2h 51m
- When
- Every day
- Estimated price
- $80–430
- Website
- united.com
Flights from Jacksonville to Chicago O'Hare International Airport
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $80–430
- Website
- flyfrontier.com
Flights from Jacksonville to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 6h 16m
- When
- Saturday
- Estimated price
- $80–430
Flights from Orlando to Chicago Midway International Airport
- Ave. Duration
- 3h 3m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $75–410
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Chicago Union Station
- Ave. Duration
- 35h 16m
- Frequency
- Once daily
- Estimated price
- $200–700
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Gainesville to Atlanta - Civic Center MARTA Station
- Ave. Duration
- 5h 20m
- Frequency
- Twice daily
- Estimated price
- $26–140
- Website
- https://www.redcoachusa.com
- Web
- $26–140
Bus from Gainesville to Orlando RedCoach Station
- Ave. Duration
- 2h 5m
- Frequency
- Every 4 hours
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $80–170
- Schedules at
- flixbus.com
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–22
- Schedules at
- flixbus.com
Bus from Gainesville to Atlanta Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 3 times a day
- Estimated price
- $45–75
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $80–170
- Website
- https://www.greyhound.com/
Bus from Gainesville Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $45–140
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Chicago Train Station
- Ave. Duration
- 15h 55m
- Frequency
- Twice daily
- Estimated price
- $80–170
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Yes, the driving distance between Gainesville to Chicago, IL is 1009 miles. It takes approximately 17h 51m to drive from Gainesville to Chicago, IL.
Book your Gainesville to Chicago, IL bus tickets online with Omio and FlixBus.
There are 1211+ hotels available in Chicago, IL.










