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How to get fromGainesville to Chicago, ILby plane, bus (Flixbus, Greyhound), bus, train, car or bus (Greyhound)

Find Transport to Chicago, IL

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There are 10 ways to get from Gainesville to Chicago, IL by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Chicago O'Hare International Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Chicago O'Hare International Airport (ORD)plane plane GNV - ORD
    6h 45m
    $64–336
  2. Bus

    1. Take the bus from Gainesville to Atlanta - Civic Center MARTA Stationbus bus Orlando
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus FlixBus 2512 / ...
    20h 54m
    $110–309
  3. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus FlixBus 2431
    2. Take the train from Jacksonville to Chicago Union Stationtrain train Floridian
    38h 46m
    $217–725
  4. Drive 1,002.7 mi

    1. Drive from Gainesville to Chicago, ILcar car 1,002.7 mi
    17h 51m
    $183–265
  5. Fly Gainesville Regional Airport to Chicago Midway International Airport

    1. Fly from Gainesville Regional Airport (GNV) to Chicago Midway International Airport (MDW)plane plane GNV - MDW
    6h 35m
    $88–476
  6. Bus to Jacksonville, fly to Chicago Midway International Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Chicago Midway International Airport (MDW)plane plane JAX - MDW
    7h 21m
    $129–680
  7. Bus to Jacksonville, fly to Chicago O'Hare International Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Chicago O'Hare International Airport (ORD)plane plane JAX - ORD
    7h 45m
    $99–460
  8. Bus to Orlando, fly to Chicago Midway International Airport

    1. Take the bus from Gainesville to Orlando RedCoach Stationbus bus
    2. Fly from Orlando (MCO) to Chicago Midway International Airport (MDW)plane plane MCO - MDW
    7h 17m
    $102–550
  9. Bus via Gainesville

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus FlixBus N2415 / ...
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus FlixBus 2512 / ...
    21h 30m
    $127–241
  10. Bus via Gainesville Bus Stop (Greyhound)

    1. Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus bus Greyhound US0630
    2. Take the bus from Atlanta Bus Station to Chicago Train Stationbus bus Greyhound US0100
    25h 51m
    $126–312

Gainesville to Chicago, IL by bus and subway

Calendar11Weekly Services
Duration20h 54mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

What companies run services between Gainesville, FL, USA and Chicago, IL, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Chicago O'Hare International Airport (ORD) every 3 hours. Alternatively, you can take a bus from Gainesville to Chicago Bus Station via Atlanta - Civic Center MARTA Station, Civic Center Station, Garnett Station, and Atlanta Bus Station in around 20h 54m.

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