There are 8 ways to get from Frederick to Myrtle Beach by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Reagan Washington, fly to Myrtle Beach  •  4 h 35 min

  1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC eb
  2. Fly from Reagan Washington (DCA) to Myrtle Beach (MYR) DCA - MYR

$212 - $681

Cheapest option

Train, drive  •  11 h 6 min

  1. Take the train from FREDERICK MARC eb to UNION STATION MARC Washington
  2. Take the train from Washington Union Station to Dillon Amtrak
  3. Drive from Dillon Amtrak to Myrtle Beach

$74 - $190

6 alternative options

Bus to Baltimore, fly to Myrtle Beach  •  4 h 44 min

  1. Take the bus from Frederick, Md to Baltimore Downtown, Md
  2. Fly from Baltimore (BWI) to Myrtle Beach (MYR) BWI - MYR

$101 - $695

Train to Reagan Washington, fly to Wilmington, bus  •  7 h 10 min

  1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC eb
  2. Fly from Reagan Washington (DCA) to Wilmington (ILM) DCA - ILM
  3. Take the bus from Wilmington, Nc to Myrtle Beach, Sc

$142 - $423

Bus via Richmond, Va  •  14 h 15 min

  1. Take the bus from Frederick, Md to Baltimore Downtown, Md
  2. Take the bus from Baltimore Downtown, Md to Richmond, Va
  3. Take the bus from Richmond, Va to Raleigh, Nc
  4. Take the bus from Raleigh, Nc to Wilmington, Nc 381 / ...
  5. Take the bus from Wilmington, Nc to Myrtle Beach, Sc 387

$85 - $204

Train, Amtrak Thruway, bus  •  14 h 48 min

  1. Take the train from FREDERICK MARC eb to UNION STATION MARC Washington
  2. Take the train from Washington Union Station to Wilson Amtrak
  3. Take the Amtrak Thruway from Wilson, NC to Wilmington, NC
  4. Take the bus from Wilmington, Nc to Myrtle Beach, Sc 387

Bus Megabus  •  16 h 15 min

  1. Take the bus from Frederick, Md to Washington, Dc
  2. Take the bus from Washington to Fayetteville, NC
  3. Take the bus from Fayetteville, Nc to Florence, Sc
  4. Take the bus from Florence, SC to Myrtle Beach, SC

$79 - $143

Drive  •  8 h 23 min

  1. Drive from Frederick to Myrtle Beach 478.2 miles

$45 - $70

Questions & Answers

No, there is no direct bus from Frederick to Myrtle Beach. However, there are services departing from Frederick, Md and arriving at Myrtle Beach, Sc via Baltimore Downtown, Md, Richmond, Va, Raleigh, Nc and Wilmington, Nc. The journey, including transfers, takes approximately 14 h 15 min.

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The distance between Frederick and Myrtle Beach is 406 miles. The road distance is 478.2 miles.

Get driving directions

The best way to get from Frederick to Myrtle Beach without a car is to bus which takes 14 h 15 min and costs .

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It takes approximately 4 h 35 min to get from Frederick to Myrtle Beach, including transfers.

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Frederick to Myrtle Beach bus services, operated by Greyhound USA, depart from Frederick, Md station.

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The quickest flight from Reagan Washington Airport to Myrtle Beach Airport is the direct flight which takes 1 h 31 min.

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Frederick to Myrtle Beach bus services, operated by Greyhound USA, arrive at Myrtle Beach, Sc station.

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Yes, the driving distance between Frederick to Myrtle Beach is 478 miles. It takes approximately 8 h 23 min to drive from Frederick to Myrtle Beach.

Get driving directions

American Airlines offers flights from Reagan Washington Airport to Myrtle Beach Airport.

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Book your Frederick to Myrtle Beach bus tickets online with Greyhound, Greyhound and three other operators.

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Map of how to get from Frederick to Myrtle Beach.
Launch map view
  • Distance: 406.3 miles
  • Duration: 4 h 35 min

What companies run services between Frederick, MD, USA and Myrtle Beach, SC, USA?

You can take a bus from Frederick to Myrtle Beach via Baltimore Downtown, Md, Richmond, Va, Raleigh, Nc, and Wilmington, Nc in around 14 h 15 min.

Airlines
American Airlines
Website
aa.com
Flights from Reagan Washington to Myrtle Beach
Ave. Duration
1 h 31 min
When
Every day
Estimated price
$240 - $1,000
Flights from Reagan Washington to Myrtle Beach via Charlotte
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$240 - $1,000
Flights from Baltimore to Myrtle Beach via Charlotte
Ave. Duration
3 h 35 min
When
Every day
Estimated price
$250 - $1,300
Flights from Reagan Washington to Wilmington
Ave. Duration
1 h 31 min
When
Every day
Estimated price
$100 - $550
Flights from Reagan Washington to Wilmington via Charlotte
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$100 - $550
Flights from Reagan Washington to Wilmington via Philadelphia
Ave. Duration
3 h 56 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $550
Spirit Airlines
Website
spirit.com
Flights from Baltimore to Myrtle Beach
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$60 - $650
Train operators
Maryland Transit
Phone
1-866-743-3682
Website
mta.maryland.gov
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
Ave. Duration
1 h 2 min
Frequency
Twice daily
Estimated price
$5 - $8
Schedules at
mta.maryland.gov
Train from FREDERICK MARC eb to UNION STATION MARC Washington
Ave. Duration
1 h 40 min
Frequency
Twice daily
Estimated price
$7 - $10
Schedules at
mta.maryland.gov
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Washington Union Station to Dillon Amtrak
Ave. Duration
6 h 56 min
Frequency
Once daily
Estimated price
$60 - $170
Website
amtrak.com
Coach Seat
$60 - $95
Flexi Coach Seat
$110 - $160
Business Coach Seat
$110 - $170
Room
$270 - $380
Train from Washington Union Station to Wilson Amtrak
Ave. Duration
4 h 41 min
Frequency
Twice daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$80 - $120
Business Coach Seat
$85 - $120
Room
$220 - $310
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Frederick, Md to Baltimore Downtown, Md
Ave. Duration
1 h 10 min
Frequency
Every 30 minutes
Estimated price
$11 - $25
Website
greyhound.com
Economy
$11 - $16
Flexible
$19 - $25
Bus from Wilmington, Nc to Myrtle Beach, Sc
Ave. Duration
1 h 35 min
Frequency
Every 2 hours
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Baltimore Downtown, Md to Richmond, Va
Ave. Duration
3 h 20 min
Frequency
Every 20 minutes
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $45
Bus from Richmond, Va to Raleigh, Nc
Ave. Duration
2 h 55 min
Frequency
Every 10 minutes
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Raleigh, Nc to Wilmington, Nc
Ave. Duration
3 h 25 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Frederick, Md to Washington, Dc
Ave. Duration
2 h 45 min
Frequency
Every 30 minutes
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $22
Flexible
$26 - $35
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
Every 30 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Wilson, NC to Wilmington, NC
Ave. Duration
3 h 52 min
Frequency
Once daily
Website
amtrak.com
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Fayetteville, NC to Florence, SC
Ave. Duration
1 h 30 min
Frequency
Once daily
Estimated price
$19 - $30
Schedules at
southeasternstages.com
Bus from Florence, SC to Myrtle Beach, SC
Ave. Duration
1 h 30 min
Frequency
Twice daily
Estimated price
$18 - $28
Schedules at
southeasternstages.com

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