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How to get fromFrederick to Milwaukeeby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 5 ways to get from Frederick to Milwaukee by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to General Mitchell International Airport (MKE)plane plane BWI - MKE
    5h 1m
    $190–757

  2. Bus

    cheapest
    1. Take the bus from Frederick Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150
    18h 5m
    $122–192

  3. Train

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    21h 51m
    $457–735

  4. Drive  732.2 mi

    1. Drive from Frederick to Milwaukeecar car 732.2 mi
    12h 43m
    $134–193

  5. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to General Mitchell International Airport (MKE)plane plane DCA - MKE
    5h 37m
    $439–1,120

Frederick to Milwaukee by bus

Calendar7Weekly Buses
Duration18h 5mAverage Duration
Ticket$122Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frederick to Milwaukee.ExpandLaunch map view
  • Distance: 706.3 mi
  • Duration: 5h 1m

What companies run services between Frederick, MD, USA and Milwaukee, WI, USA?

You can take a bus from Frederick Bus Station to Milwaukee Intermodal Station via Chicago Bus Station in around 18h 5m. Alternatively, you can take a train from FREDERICK MARC eb to Milwaukee via Rockville Amtrak and Chicago Union Station in around 21h 51m.

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