There are 6 ways to get from Frederick to Lexington by bus, plane, car, bus (Greyhound), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly, drive
best- Take the bus from Frederick Bayrunner Office to Baltimore Airport
- Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)BWI - SDF
- Drive from Louisville-Airport-SDF to Lexington
5h 19m$263–448Drive 487.8 mi
cheapest- Drive from Frederick to Lexington487.8 mi
7h 58m$89–129Bus via Columbus
- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Station
- Take the bus from Pittsburgh Intermodal Station to Columbus Bus Station
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OH
- Take the bus from Cincinnati Bus Station to Lexington Bus Stop
13h 22m$128–345Train to Ronald Reagan Washington National Airport, fly, drive
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)DCA - SDF
- Drive from Louisville-Airport-SDF to Lexington
6h 14m$160–891Bus to Washington Dulles International Airport, fly, drive
- Take the bus from Frederick Transit Station to Market St & Harrison St
- Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)IAD - SDF
- Drive from Louisville-Airport-SDF to Lexington
6h 27m$288–797Bus (Greyhound)
- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Station
- Take the bus from Pittsburgh Intermodal Station to Dayton Trotwood Bus Station
- Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stop
15h 7m$145–315
Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Frederick to Lexington is to drive which costs $85 - $130 and takes 7h 58m.
The fastest way to get from Frederick to Lexington is to bus and fly and drive which takes 5h 19m and costs $260 - $450.
The distance between Frederick and Lexington is 625 miles. The road distance is 490.6 miles.
The best way to get from Frederick to Lexington without a car is to bus via Columbus which takes 13h 22m and costs $120 - $350.
It takes approximately 5h 19m to get from Frederick to Lexington, including transfers.
Yes, the driving distance between Frederick to Lexington is 491 miles. It takes approximately 7h 58m to drive from Frederick to Lexington.
There are 137+ hotels available in Lexington.
What companies run services between Frederick, MD, USA and Lexington, KY, USA?
You can take a bus from Frederick Bus Station to Lexington via Pittsburgh Intermodal Station, N Wilson Rd & Ferrell Pl - Columbus, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 13h 22m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Louisville International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $85–480
Flights from Baltimore-Washington International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Wednesday, Thursday, and Saturday
- Estimated price
- $180–1,000
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h 10m
- When
- Wednesday and Thursday
- Estimated price
- $200–1,100
- Website
- aa.com
Flights from Baltimore-Washington International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $100–550
Flights from Ronald Reagan Washington National Airport to Louisville International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $140–850
Flights from Ronald Reagan Washington National Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $170–950
Flights from Washington Dulles International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–550
- Website
- united.com
Flights from Washington Dulles International Airport to Louisville International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $80–470
- Website
- delta.com
Flights from Washington Dulles International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–10
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- bayrunnershuttle.com
Bus from Frederick Bayrunner Office to Baltimore Airport
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Frederick Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $35–120
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to Columbus Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OH
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
Bus from Cincinnati Bus Station to Lexington Bus Stop
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $19–60
- Website
- https://www.greyhound.com/
Bus from Pittsburgh Intermodal Station to Dayton Trotwood Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
Bus from Dayton Trotwood Bus Station to Lexington Bus Stop
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OH
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 703-771-5665
- Website
- loudoun.gov
Bus from Frederick Transit Station to Market St & Harrison St
- Ave. Duration
- 58 min
- Frequency
- Once daily
- Estimated price
- $1–11
- Schedules at
- loudoun.gov
- Local & Metro
- $1–2
- Commuter
- $11
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