There are 11 ways to get from Frederick to Lexington by bus, plane, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly to Covington, drive
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Covington (CVG)plane BWI - CVG
- Drive from Covington (CVG) to Lexingtoncar
5h 26m$212–976Bus to Washington Dulles International Airport, fly to Dayton, drive
cheapest- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Dayton (DAY)plane IAD - DAY
- Drive from Dayton-Airport-DAY to Lexingtoncar
7h 14m$81–395Bus, drive via Pittsburgh
- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to Columbusbus
- Take the bus from Columbus to Louisvillebus
- Drive from Middletown Station @ Target to Lexingtoncar
17h 28m$102–183Drive 487.7 mi
- Drive from Frederick to Lexingtoncar 487.7 mi
8h 3m$89–129Bus to Baltimore-Washington International Airport, fly to Louisville International Airport, drive
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane BWI - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
5h 34m$201–775Train to Ronald Reagan Washington National Airport, fly to Covington, drive
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Covington (CVG)plane DCA - CVG
- Drive from Covington (CVG) to Lexingtoncar
6h$142–1,139Bus to Washington Dulles International Airport, fly to Covington, drive
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Covington (CVG)plane IAD - CVG
- Drive from Covington (CVG) to Lexingtoncar
6h 9m$139–477Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane DCA - LEX
6h 48m$94–569Bus to Washington Dulles International Airport, fly to Louisville International Airport, drive
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane IAD - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
6h 18m$108–596Bus, drive (Greyhound)
- Take the bus from Frederick Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo Bus Stop to Louisville Bus Stationbus
- Drive from Middletown Station @ Target to Lexingtoncar
20h 18m$126–216Train, bus, drive
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the bus from Washington Union Station to Robert K Pfaff Transit Center - Akronbus
- Take the bus from Robert K Pfaff Transit Center - Akron to Louisville, KY Bus Stationbus
- Drive from Middletown Station @ Target to Lexingtoncar
23h 33m$101–211
Baltimore-Washington International Airport (BWI) to Covington (CVG) flights
Questions & Answers
The cheapest way to get from Frederick to Lexington is to drive which costs $85 - $130 and takes 8h 3m.
The fastest way to get from Frederick to Lexington is to bus and fly and drive which takes 5h 26m and costs $210 - $1,000.
The distance between Frederick and Lexington is 573 miles. The road distance is 490.6 miles.
It takes approximately 5h 26m to get from Frederick to Lexington, including transfers.
Yes, the driving distance between Frederick to Lexington is 491 miles. It takes approximately 8h 3m to drive from Frederick to Lexington.
There are 178+ hotels available in Lexington.
What companies run services between Frederick, MD, USA and Lexington, KY, USA?
There is no direct connection from Frederick to Lexington. However, you can take the bus to Baltimore, walk to Baltimore-Washington International Airport (BWI) airport, fly to Covington (CVG), then drive to Lexington. Alternatively, you can take a bus from Frederick Bus Station to Lexington via Pittsburgh Intermodal Station, Columbus, Louisville, Chestnut @ 13th, Chestnut @ 8th, S 5th @ W Jefferson, and Middletown Station @ Target in around 17h 28m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Covington
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $100–650
Flights from Baltimore-Washington International Airport to Covington via Nashville
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–800
Flights from Baltimore-Washington International Airport to Louisville International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $110–650
Flights from Ronald Reagan Washington National Airport to Covington via Nashville
- Ave. Duration
- 3h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $200–1,100
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
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