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How to get fromFrederick to Lexingtonby bus, plane, car, bus (Greyhound) or train

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There are 7 ways to get from Frederick to Lexington by bus, plane, car, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Louisville International Airport, drive

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    5h 24m
    $263–708

  2. Drive 487.8 mi

    cheapest
    1. Drive from Frederick to Lexingtoncar car 487.8 mi
    8h 3m
    $89–129

  3. Bus via Columbus

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Cincinnati, OHbus bus
    4. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    13h 57m
    $125–236

  4. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    25h 58m
    $179–449

  5. Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    6h 54m
    $108–672

  6. Bus to Washington Dulles International Airport, fly to Louisville International Airport, drive

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    6h 33m
    $258–527

  7. Bus (Greyhound)

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Dayton Trotwood Bus Stationbus bus
    3. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus
    15h 57m
    $117–217

Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF) flights

Calendar42Weekly Planes
Duration3h 11mAverage Duration
Ticket$83Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Lexington, KY, USA?

You can take a bus from Frederick Bus Station to Lexington via Pittsburgh Intermodal Station, N Wilson Rd & Ferrell Pl - Columbus, Cincinnati, OH, Cincinnati Bus Station, and Lexington Bus Stop in around 13h 57m.

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