There are 7 ways to get from Frederick to Jacksonville by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Jacksonville (JAX)plane BWI - JAX
6h 3m$178–707Train, subway to Washington Dulles International Airport, fly
cheapest- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Jacksonville (JAX)plane IAD - JAX
7h 8m$87–479Bus
- Take the bus from Frederick Bus Station to Washington Union Stationbus Greyhound US0164 / ...
- Take the bus from Washington Union Station to Jacksonvillebus FlixBus N2472 / ...
15h 55m$118–182Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain Marc
- Take the train from Washington Union Station to Jacksonvilletrain Silver Meteor / ...
17h 28m$413–665Drive 744.3 mi
- Drive from Frederick to Jacksonvillecar 744.3 mi
12h 23m$136–197Train to Ronald Reagan Washington National Airport, fly
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Jacksonville (JAX)plane DCA - JAX
6h 38m$127–720Train via Rockville
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain Marc
- Take the train from Rockville Amtrak to Jacksonvilletrain Floridian
20h 57m$443–713
Frederick to Jacksonville by bus
Comparing Your Travel Options
The cheapest way to get from Frederick to Jacksonville is to bus which costs $110 - $190 and takes 15h 55m.
The fastest way to get from Frederick to Jacksonville is to bus and fly which takes 6h 3m and costs $170 - $750.
No, there is no direct bus from Frederick station to Jacksonville. However, there are services departing from Frederick Bus Station and arriving at Jacksonville via Washington Union Station. The journey, including transfers, takes approximately 15h 55m.
No, there is no direct train from Frederick to Jacksonville. However, there are services departing from FREDERICK MARC eb and arriving at Jacksonville via Washington Union Station. The journey, including transfers, takes approximately 17h 28m.
The distance between Frederick and Jacksonville is 746 miles. The road distance is 748.7 miles.
The best way to get from Frederick to Jacksonville without a car is to bus which takes 15h 55m and costs $110 - $190.
It takes approximately 6h 3m to get from Frederick to Jacksonville, including transfers.
Frederick to Jacksonville bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to Jacksonville train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to Jacksonville is to bus which takes 15h 55m and costs $110 - $190. Alternatively, you can train, which costs $410 - $700 and takes 17h 28m.
What companies run services between Frederick, MD, USA and Jacksonville, FL, USA?
You can take a bus from Frederick Bus Station to Jacksonville via Washington Union Station in around 15h 55m. Alternatively, you can take a train from FREDERICK MARC eb to Jefferson St + Beaver St via Washington Union Station, Jacksonville, and Amtrak Station in around 17h 28m.
- Website
- delta.com
Flights from Baltimore-Washington International Airport to Jacksonville via Atlanta
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $110–650
Flights from Ronald Reagan Washington National Airport to Jacksonville via Atlanta
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $140–800
Flights from Washington Dulles International Airport to Jacksonville via Atlanta
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $95–500
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Jacksonville
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Baltimore-Washington International Airport to Jacksonville via Charlotte
- Ave. Duration
- 4h 6m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Ronald Reagan Washington National Airport to Jacksonville
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $120–700
Flights from Ronald Reagan Washington National Airport to Jacksonville via Charlotte
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $120–750
Flights from Washington Dulles International Airport to Jacksonville via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $80–460
- Website
- united.com
Flights from Washington Dulles International Airport to Jacksonville
- Ave. Duration
- 2h 18m
- When
- Every day
- Estimated price
- $80–460
- Website
- allegiantair.com
Flights from Washington Dulles International Airport to Jacksonville
- Ave. Duration
- 2h 1m
- When
- Friday
- Estimated price
- $80–460
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Washington Union Station to Jacksonville
- Ave. Duration
- 14h
- Frequency
- Twice daily
- Estimated price
- $410–650
- Website
- Amtrak
Train from Rockville Amtrak to Jacksonville
- Ave. Duration
- 18h 11m
- Frequency
- Once daily
- Estimated price
- $440–700
- Website
- Amtrak
Subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 51 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Frederick Bus Station to Washington Union Station
- Ave. Duration
- 1h 10m
- Frequency
- 3 times a day
- Estimated price
- $8–12
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Washington Union Station to Jacksonville
- Ave. Duration
- 13h 45m
- Frequency
- Once daily
- Estimated price
- $110–170
- Schedules at
- Flixbus USA
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Booking & Getting There
Frederick to Jacksonville bus services, operated by Greyhound USA, arrive at Washington Union Station.
Frederick to Jacksonville train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Jacksonville is 749 miles. It takes approximately 12h 23m to drive from Frederick to Jacksonville.
Book your Frederick to Jacksonville bus tickets online with Omio and FlixBus.
There are 566+ hotels available in Jacksonville.



















