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How to get fromFrederick to Ithacaby bus, train, car, subway, plane, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Frederick to Ithaca by bus, train, car, subway, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Newark Penn Stationtrain train
    3. Take the bus from Newark Penn Station to Ithacabus bus
    9h 40m

  2. Drive  256 mi

    cheapest
    1. Drive from Frederick to Ithacacar car 256 mi
    5h 45m
    $47–68

  3. Train, subway to Washington Dulles International Airport, fly to Ithaca Tompkins Regional Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Ithaca Tompkins Regional Airport (ITH)plane plane IAD - ITH
    6h 12m
    $51–336

  4. Bus

    1. Take the bus from Frederick Bus Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Washington Union Station to Ithacabus bus FlixBus 2682
    12h 10m
    $83–132

  5. Bus to Baltimore-Washington International Airport, fly to Rochester, bus

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Rochester (ROC)plane plane BWI - ROC
    3. Take the bus from Rochester to Ithacabus bus
    6h 39m
    $226–983

  6. Train, subway to Washington Dulles International Airport, fly to Rochester, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Rochester (ROC)plane plane IAD - ROC
    4. Take the bus from Rochester to Ithacabus bus
    7h 49m
    $145–795

  7. Train to Ronald Reagan Washington National Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Syracuse Hancock International Airport (SYR)plane plane DCA - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 34m
    $178–1,159

  8. Train, subway to Washington Dulles International Airport, fly to Wilkes-Barre/Scranton International Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Wilkes-Barre/Scranton International Airport (AVP)plane plane IAD - AVP
    4. Take the bus from Scranton, Pa to Ithacabus bus
    8h 24m
    $113–461

  9. Train, subway to Washington Dulles International Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Syracuse Hancock International Airport (SYR)plane plane IAD - SYR
    4. Take the bus from Syracuse Bus Station to Ithacabus bus
    8h 10m
    $118–758

Frederick to Ithaca by bus

Calendar5Weekly Buses
Duration12h 10mAverage Duration
Ticket$83Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frederick to Ithaca.ExpandLaunch map view
  • Distance: 446.2 mi
  • Duration: 9h 40m

What companies run services between Frederick, MD, USA and Ithaca, NY, USA?

You can take a bus from Frederick Bus Station to Ithaca via Washington Union Station in around 12h 10m.

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