There are 9 ways to get from Frederick to Indiana by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly to Indianapolis
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane BWI - IND
5h 16m$479–1,006Train, subway to Washington Dulles International Airport, fly to South Bend
cheapest- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to South Bend (SBN)plane IAD - SBN
- Take the train from South Bend Airport to Gary Metro Centertrain
7h 26m$77–399Bus
- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0164 / ...
- Take the bus from Pittsburgh Intermodal Station to Indianapolisbus FlixBus N2642 / ...
12h 30m$88–134Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain Marc
- Take the train from Washington Union Station to Indianapolistrain Cardinal
20h 56m$392–662Drive 518.1 mi
- Drive from Frederick to Indianapoliscar 518.1 mi
9h 14m$95–137Train to Ronald Reagan Washington National Airport, fly to Indianapolis
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane DCA - IND
5h 53m$958–1,319Train, subway to Washington Dulles International Airport, fly to Indianapolis
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane IAD - IND
6h 18m$558–1,118Bus to Baltimore-Washington International Airport, fly to Chicago Midway International Airport, train
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane BWI - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 10m$207–419Train to Ronald Reagan Washington National Airport, fly to Chicago Midway International Airport, train
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Chicago Midway International Airport (MDW)plane DCA - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
6h 36m$116–632
Frederick to Indiana by bus
Comparing Your Travel Options
The cheapest way to get from Frederick to Indiana is to bus which costs $85 - $140 and takes 12h 30m.
The fastest way to get from Frederick to Indiana is to bus and fly which takes 5h 16m and costs $470 - $1,100.
No, there is no direct bus from Frederick station to Indiana. However, there are services departing from Frederick Bus Station and arriving at Indianapolis via Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 12h 30m.
No, there is no direct train from Frederick to Indiana. However, there are services departing from FREDERICK MARC eb and arriving at Indianapolis via Washington Union Station. The journey, including transfers, takes approximately 20h 56m.
The distance between Frederick and Indiana is 593 miles. The road distance is 521.2 miles.
The best way to get from Frederick to Indiana without a car is to bus which takes 12h 30m and costs $85 - $140.
It takes approximately 5h 16m to get from Frederick to Indiana, including transfers.
Frederick to Indiana bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to Indiana train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to Indiana is to bus which takes 12h 30m and costs $85 - $140. Alternatively, you can train, which costs $390 - $700 and takes 20h 56m.
What companies run services between Frederick, MD, USA and Indiana, USA?
You can take a bus from Frederick Bus Station to Indianapolis via Pittsburgh Intermodal Station in around 12h 30m. Alternatively, you can take a train from FREDERICK MARC eb to Indianapolis via Washington Union Station in around 20h 56m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Indianapolis
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $100–650
Flights from Baltimore-Washington International Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Ronald Reagan Washington National Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $170–900
Flights from Ronald Reagan Washington National Airport to Indianapolis via Nashville
- Ave. Duration
- 4h 18m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $170–950
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $80–450
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport via Pittsburgh
- Ave. Duration
- 3h 25m
- When
- Saturday
- Estimated price
- $80–450
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport via Columbus
- Ave. Duration
- 3h 25m
- When
- Tuesday and Wednesday
- Estimated price
- $80–450
Flights from Ronald Reagan Washington National Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $100–600
Flights from Ronald Reagan Washington National Airport to Chicago Midway International Airport via Columbus
- Ave. Duration
- 4h 27m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $100–600
- Website
- delta.com
Flights from Baltimore-Washington International Airport to Indianapolis via Detroit
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $110–650
Flights from Ronald Reagan Washington National Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $150–850
Flights from Washington Dulles International Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $95–550
Flights from Washington Dulles International Airport to Indianapolis via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $130–650
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–460
Flights from Ronald Reagan Washington National Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $100–600
Flights from Washington Dulles International Airport to South Bend via Detroit
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $65–380
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Indianapolis
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $130–800
Flights from Ronald Reagan Washington National Airport to Indianapolis via Charlotte
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $170–900
Flights from Washington Dulles International Airport to Indianapolis via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $110–600
- Website
- united.com
Flights from Washington Dulles International Airport to Indianapolis
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $85–550
Flights from Washington Dulles International Airport to South Bend
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $60–370
Flights from Washington Dulles International Airport to South Bend via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $70–400
- Website
- flybreeze.com
Flights from Washington Dulles International Airport to South Bend
- Ave. Duration
- 1h 56m
- When
- Monday and Friday
- Estimated price
- $130–900
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Washington Union Station to Indianapolis
- Ave. Duration
- 18h 16m
- Frequency
- 3 times a week
- Estimated price
- $390–650
- Website
- Amtrak
Subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 51 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
Subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 51 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Every 30 minutes
- Estimated price
- $8–10
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $8–10
Train from South Bend Airport to Gary Metro Center
- Ave. Duration
- 1h 11m
- Frequency
- Every 4 hours
- Estimated price
- $11–13
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $11–13
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- $4–9
- Schedules at
- Northern Indiana Commuter Transportation District
Train from South Bend Airport to Gary Metro Center
- Ave. Duration
- 1h 11m
- Frequency
- 4 times a day
- Estimated price
- $3–14
- Schedules at
- Northern Indiana Commuter Transportation District
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Frederick Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Pittsburgh Intermodal Station to Indianapolis
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $55–85
- Schedules at
- Flixbus USA
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Booking & Getting There
Frederick to Indiana bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Frederick to Indiana train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Indiana is 521 miles. It takes approximately 9h 14m to drive from Frederick to Indiana.
Book your Frederick to Indiana bus tickets online with Omio and FlixBus.
There are 735+ hotels available in Indiana.



















