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How to get fromFrederick to Hyannisby train, plane, bus, bus (Flixbus, Greyhound), car, or subway

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There are 8 ways to get from Frederick to Hyannis by train, plane, bus, bus (Flixbus, Greyhound), car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly to Barnstable Municipal Airport

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Barnstable Municipal Airport (HYA)plane plane DCA - HYA
    4h 30m
    $116–717

  2. Drive  475.5 mi

    cheapest
    1. Drive from Frederick to Hyanniscar car 475.5 mi
    9h 13m
    $87–126

  3. Bus, train

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Bostontrain train
    3. Take the bus from Boston to Hyannisbus bus
    11h 21m

  4. Bus

    1. Take the bus from Frederick to Baltimorebus bus
    2. Take the bus from Baltimore Downtown Bus Station to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    12h 42m
    $165–259

  5. Bus to Baltimore-Washington International Airport, fly to Boston Logan Airport, bus

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Boston Logan Airport (BOS)plane plane BWI - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 51m
    $255–1,094

  6. Train, subway to Washington Dulles International Airport, fly to Boston Logan Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Boston Logan Airport (BOS)plane plane IAD - BOS
    4. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 59m
    $534–1,156

  7. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    11h 58m
    $279–437

  8. Bus via New York

    1. Take the bus from Frederick to Baltimorebus bus
    2. Take the bus from Baltimore to New Yorkbus bus
    3. Take the bus from New York to Providencebus bus
    4. Take the bus from Providence to Hyannisbus bus
    13h 17m
    $163–282

Frederick to Hyannis by bus

Calendar20Weekly Buses
Duration12h 42mAverage Duration
Ticket$165Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frederick to Hyannis.ExpandLaunch map view
  • Distance: 466 mi
  • Duration: 4h 30m

What companies run services between Frederick, MD, USA and Hyannis, MA, USA?

You can take a bus from Frederick to Hyannis Transportation Center via Baltimore Downtown Bus Station, Boston, and Boston South Buses in around 12h 42m.

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