Rome2Rio

How to get fromFrederick to Hyannisby train, plane, bus, bus (Flixbus, Greyhound), or car

Find Transport to Hyannis

See all options

There are 8 ways to get from Frederick to Hyannis by train, plane, bus, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly to Barnstable Municipal Airport

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Barnstable Municipal Airport (HYA)plane plane DCA - HYA
    6h 11m
    $117–717

  2. Drive  475.5 mi

    cheapest
    1. Drive from Frederick to Hyanniscar car 475.5 mi
    9h 13m
    $87–126

  3. Bus, train

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    10h 48m
    $205–389

  4. Bus

    1. Take the bus from Frederick Bayrunner Office to Baltimore Downtown Bus Terminal, Baltimore, MDbus bus
    2. Take the bus from Baltimore Downtown Bus Station to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    12h 46m
    $160–259

  5. Bus to Baltimore-Washington International Airport, fly to Boston Logan Airport, bus

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Boston Logan Airport (BOS)plane plane BWI - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 23m
    $245–1,094

  6. Bus to Washington Dulles International Airport, fly to Boston Logan Airport, bus

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Boston Logan Airport (BOS)plane plane IAD - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    7h 20m
    $532–1,165

  7. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    11h 37m
    $149–317

  8. Bus via New York

    1. Take the bus from Frederick Bayrunner Office to Baltimore Downtown Bus Terminal, Baltimore, MDbus bus
    2. Take the bus from Baltimore to New Yorkbus bus
    3. Take the bus from New York to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    13h 6m
    $180–299

Frederick to Hyannis by bus and train

Calendar52Weekly Services
Duration10h 48mAverage Duration
Ticket$205Cheapest Price
See schedules

Questions & Answers

Map of how to get from Frederick to Hyannis.ExpandLaunch map view
  • Distance: 465.8 mi
  • Duration: 6h 11m

What companies run services between Frederick, MD, USA and Hyannis, MA, USA?

You can take a bus from Frederick Bayrunner Office to Hyannis Transportation Center via Baltimore Downtown Bus Station, Boston, and Boston South Buses in around 12h 46m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers