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How to get fromFrederick to Florida Keysby train, plane, bus (Greyhound, Flixbus), bus, car or shuttle

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There are 12 ways to get from Frederick to Florida Keys by train, plane, bus (Greyhound, Flixbus), bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly to Key West International Airport

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Key West International Airport (EYW)planeDCA - EYW
    8h 49m
    $243–1,039

  2. Train, bus via Delray Beach

    cheapest
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Take the train from Rockville Amtrak to Delray Beach Amtraktrain
    3. Take the train from Delray Beach Station to Miami Airport Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    38h 36m
    $141–423

  3. Bus

    1. Take the bus from Frederick Bus Station to Washington Union Stationbus
    2. Take the bus from Washington Union Station to Orlando Bus Stationbus
    3. Take the bus from Orlando Bus Station to Miami Airport Stationbus
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    30h 17m
    $154–414

  4. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain
    2. Take the train from Washington Union Station to Fort Lauderdale Amtrak Stationtrain
    3. Take the train from Fort Lauderdale Station to Miami Airport Stationtrain
    4. Take the bus from Miami Airport Station to Big Pine Keybus
    32h 49m
    $160–862

  5. Drive 1,231.6 mi

    1. Drive from Frederick to Florida Keyscar1,231.6 mi
    20h 52m
    $225–325

  6. Bus to Washington Dulles International Airport, fly to Key West International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus
    2. Fly from Washington Dulles International Airport (IAD) to Key West International Airport (EYW)planeIAD - EYW
    9h 20m
    $151–645

  7. Bus to Baltimore-Washington International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
    2. Fly from Baltimore-Washington International Airport (BWI) to Miami International Airport (MIA)planeBWI - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    10h 10m
    $286–620

  8. Bus to Baltimore-Washington International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
    2. Fly from Baltimore-Washington International Airport (BWI) to Fort Lauderdale–Hollywood International Airport (FLL)planeBWI - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    10h 35m
    $266–510

  9. Train to Ronald Reagan Washington National Airport, fly to Miami International Airport, shuttle

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Miami International Airport (MIA)planeDCA - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    11h 9m
    $278–904

  10. Train to Ronald Reagan Washington National Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Fort Lauderdale–Hollywood International Airport (FLL)planeDCA - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle
    11h 29m
    $258–774

  11. Bus to Washington Dulles International Airport, fly to Miami International Airport, shuttle

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus
    2. Fly from Washington Dulles International Airport (IAD) to Miami International Airport (MIA)planeIAD - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle
    11h 20m
    $201–580

  12. Bus, train to Philadelphia International Airport, fly to Key West International Airport

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
    3. Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)planePHL - EYW
    10h 42m
    $209–2,106

Frederick to Florida Keys by bus and foot

Calendar5Weekly Services
Duration30h 17mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Florida Keys, FL, USA?

You can take a bus from Frederick Bus Station to Florida Keys via Washington Union Station, Orlando Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 30h 17m.

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