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How to get fromFrederick to Des MoinesBy train, plane, bus (Greyhound), bus, or car

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There are 7 ways to get from Frederick to Des Moines by train, plane, bus (Greyhound), bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    5h 50m
    $333–1,641

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Frederick Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    22h 55m
    $157–313

  3. Train, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    26h 53m
    $252–560

  4. Drive 960 mi

    1. Drive from Frederick to Des Moinescar car 960 mi
    16h 15m
    $176–254

  5. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM)plane plane BWI - DSM
    6h 47m
    $266–1,058

  6. Bus to Washington Dulles International Airport, fly

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Des Moines (DSM)plane plane IAD - DSM
    8h 3m
    $181–897

  7. Train, bus via Bloomington

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    29h 47m
    $277–615

Frederick to Des Moines by bus (Greyhound)

Calendar7Weekly Buses
Duration22h 55mAverage Duration
Ticket$157Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Des Moines, IA, USA?

You can take a bus from Frederick Bus Station to Des Moines via Chicago Bus Station in around 22h 55m.

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