Rome2Rio

How to get fromFrederick to Des Moinesby train, plane, bus (Greyhound), bus, car, or subway

Find Transport to Des Moines

See all options

There are 8 ways to get from Frederick to Des Moines by train, plane, bus (Greyhound), bus, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    5h 53m
    $154–740

  2. Train, subway to Washington Dulles International Airport, fly

    cheapest
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Des Moines (DSM)plane plane IAD - DSM
    8h 8m
    $109–489

  3. Bus (Greyhound)

    1. Take the bus from Frederick Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    22h 55m
    $158–252

  4. Train, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    27h 1m
    $252–645

  5. Drive  960 mi

    1. Drive from Frederick to Des Moinescar car 960 mi
    16h 15m
    $176–254

  6. Bus to Baltimore-Washington International Airport, fly

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Des Moines (DSM)plane plane BWI - DSM
    6h 56m
    $195–677

  7. Bus, train to Philadelphia International Airport, fly

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    3. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    7h 49m
    $165–1,292

  8. Train, bus via Galesburg

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    28h 53m
    $272–735

Frederick to Des Moines by bus (Greyhound)

Calendar7Weekly Buses
Duration22h 55mAverage Duration
Ticket$158Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Frederick to Des Moines.ExpandLaunch map view
  • Distance: 961.1 mi
  • Duration: 5h 53m

What companies run services between Frederick, MD, USA and Des Moines, IA, USA?

You can take a bus from Frederick Bus Station to Des Moines via Chicago Bus Station in around 22h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There