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  • Deutsche Bahn
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There are 10 ways to get from Frankfurt am Main to Sicily by plane, train, bus, bus and ferry, car or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Frankfurt to Palermo  •  5h 45m

  1. Fly from Frankfurt (FRA) to Palermo (PMO) FRA - PMO

$98 - $303

9 alternative options

Fly Frankfurt to Catania  •  5h 31m

  1. Fly from Frankfurt (FRA) to Catania (CTA) FRA - CTA

$98 - $400

Fly Frankfurt to Trapani  •  8h 3m

  1. Fly from Frankfurt (FRA) to Trapani (TPS) FRA - TPS

$266 - $1,211

Fly Frankfurt to Comiso  •  8h 14m

  1. Fly from Frankfurt (FRA) to Comiso (CIY) FRA - CIY

$163 - $820

Train to Cologne Bonn, fly to Palermo  •  6h 44m

  1. Take the train from Frankfurt(Main)Hbf to Köln/Bonn Flughafen
  2. Fly from Cologne Bonn (CGN) to Palermo (PMO) CGN - PMO

$117 - $343

Train via Roma Termini  •  24h 29m

  1. Take the train from Frankfurt(Main)Hbf to Milano Centrale Ece / ...
  2. Take the train from Milano Centrale to Roma Termini Fr
  3. Take the train from Roma Termini to Palermo Centrale Ic / ...

$218 - $445

Bus Busitalia Simet S.p.A., bus and ferry  •  29h 24m

  1. Take the bus from Frankfurt to Termoli
  2. Take the bus and ferry from Termoli to Palermo

$144 - $207

Drive, ferry  •  25h 31m

  1. Drive from Frankfurt am Main to Genoa
  2. Take the ferry from Genoa to Palermo

$208 - $338

Train  •  30h 1m

  1. Take the train from Frankfurt(Main)Hbf to Milano Centrale Ece / ...
  2. Take the train from Milano Centrale to Palermo Centrale Icn

$238 - $440

Bus, bus and ferry Eurolines CH  •  31h 41m

  1. Take the bus from Frankfurt, Frankfurt central station to Zurich 007 / ...
  2. Take the bus and ferry from Zurich to Palermo

$157 - $203

Questions & Answers

The cheapest way to get from Frankfurt am Main to Sicily is to bus and bus and ferry which costs 130€ - 180€ and takes 31h 41m.

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The quickest way to get from Frankfurt am Main to Sicily is to fly which costs 85€ - 350€ and takes 5h 31m.

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No, there is no direct bus from Frankfurt am Main to Sicily. However, there are services departing from Frankfurt and arriving at Palermo via Termoli. The journey, including transfers, takes approximately 29h 24m.

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No, there is no direct train from Frankfurt am Main to Sicily. However, there are services departing from Frankfurt(Main)Hbf and arriving at Palermo Notarbartolo via Milano Centrale, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 24h 29m.

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The distance between Frankfurt am Main and Sicily is 1459 km.

The best way to get from Frankfurt am Main to Sicily without a car is to train which takes 24h 29m and costs 190€ - 390€.

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It takes approximately 5h 45m to get from Frankfurt am Main to Sicily, including transfers.

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Frankfurt am Main to Sicily bus services, operated by Busitalia Simet S.p.A., depart from Frankfurt station.

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Frankfurt am Main to Sicily train services, operated by Deutsche Bahn, depart from Frankfurt(Main)Hbf station.

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The best way to get from Frankfurt am Main to Sicily is to fly which takes 5h 45m and costs 85€ - 270€. Alternatively, you can train, which costs 190€ - 390€ and takes 24h 29m.

Mode details

Map of how to get from Frankfurt am Main to Sicily.
Launch map view
  • Distance: 912.2 miles
  • Duration: 5h 45m

What companies run services between Frankfurt am Main, Germany and Sicily, Italy?

Lufthansa and Alitalia fly from Frankfurt am Main to Palermo 3 times a day. Alternatively, you can take a train from Frankfurt am Main to Palermo via Milano Centrale, Roma Termini, and Palermo Centrale in around 24h 29m.

Airlines
Alitalia
Website
alitalia.com
Flights from Frankfurt to Palermo via Rome
Ave. Duration
4h 25m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $500
Flights from Frankfurt to Palermo via Milan Linate
Ave. Duration
4h 45m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $500
Flights from Frankfurt to Catania via Milan Linate
Ave. Duration
4h 52m
When
Every day
Estimated price
$180 - $700
Flights from Frankfurt to Catania via Rome
Ave. Duration
4h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $700
Flights from Frankfurt to Trapani via Milan Malpensa
Ave. Duration
4h 22m
When
Monday to Saturday
Estimated price
$190 - $1,100
Flights from Frankfurt to Trapani via Milan Linate
Ave. Duration
6h 5m
When
Every day
Estimated price
$190 - $1,100
Flights from Frankfurt to Comiso via Rome
Ave. Duration
4h 20m
When
Monday, Tuesday, Thursday and Friday
Estimated price
$550 - $2,500
Flights from Frankfurt to Comiso via Venice, Rome
Ave. Duration
6h 15m
When
Monday, Tuesday, Thursday and Friday
Estimated price
$550 - $2,500
Flights from Frankfurt to Comiso via Bologna, Rome
Ave. Duration
6h 25m
When
Monday, Tuesday, Thursday and Friday
Estimated price
$550 - $2,500
Flights from Frankfurt to Comiso via Milan Linate, Rome
Ave. Duration
6h 30m
When
Monday, Tuesday, Thursday and Friday
Estimated price
$330 - $1,800
Ryanair
Website
ryanair.com
Flights from Frankfurt to Catania
Ave. Duration
2h 30m
When
Monday, Wednesday and Friday
Estimated price
$50 - $270
Flights from Frankfurt to Trapani via Cagliari
Ave. Duration
4h 30m
When
Sunday
Estimated price
$360 - $1,600
Flights from Frankfurt to Comiso via Rome
Ave. Duration
5h 50m
When
Monday
Estimated price
$320 - $1,800
Flights from Frankfurt to Comiso via Milan Malpensa
Ave. Duration
7h 55m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$150 - $800
Flights from Cologne Bonn to Palermo
Ave. Duration
2h 30m
When
Wednesday and Saturday
Estimated price
$140 - $320
Flights from Cologne Bonn to Palermo via Berlin Schoenefeld
Ave. Duration
5h 45m
When
Monday and Friday
Estimated price
$140 - $320
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Palermo
Ave. Duration
2h 15m
When
Saturday
Estimated price
$260 - $1,200
Flights from Frankfurt to Catania
Ave. Duration
2h 25m
When
Sunday
Estimated price
$290 - $1,000
Flights from Frankfurt to Catania via Munich
Ave. Duration
3h 50m
When
Friday
Estimated price
$290 - $1,000
Eurowings
Website
eurowings.com
Flights from Cologne Bonn to Palermo
Ave. Duration
2h 25m
When
Saturday
Estimated price
$170 - $750
Flights from Cologne Bonn to Palermo via Munich
Ave. Duration
4h 10m
When
Thursday
Estimated price
$180 - $750
Condor Flugdienst
Website
condor.com
Flights from Frankfurt to Catania
Ave. Duration
2h 25m
When
Saturday
Estimated price
$210 - $900
KLM
Website
klm.com
Flights from Frankfurt to Catania via Amsterdam Schiphol
Ave. Duration
5h 10m
When
Monday, Friday and Saturday
Estimated price
$160 - $600
Brussels Airlines
Website
brusselsairlines.com
Flights from Frankfurt to Comiso via Brussels
Ave. Duration
6h 30m
When
Saturday
Estimated price
$350 - $1,400
Train operators
Deutsche Bahn

Deutsche Bahn is the German railway company, and the largest railway operator and infrastructure owner in Europe. Based in Berlin, Deutsche Bahn was founded in 1994, and offers many different types of rail transportation including ICE or Intercity-Express for high-speed services between major cities and regions, IC (InterCity) for long-distance trains, RE (Regional Express) trains that connect regions and cities, and the S-Bahn rapid transit service. There are two main tickets on offer: the Flexpreis that has full flexibility, and the Sparpreis which is the cheaper, advanced fare.

Contact Details
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Frankfurt(Main)Hbf to Köln/Bonn Flughafen
Ave. Duration
1h 2m
Frequency
5 times a day
Estimated price
$35 - $60
Website
bahn.de
Train from Frankfurt(Main)Hbf to Milano Centrale
Ave. Duration
7h 34m
Frequency
Once daily
Estimated price
$140 - $250
Website
bahn.de
Trenitalia Eurocity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Frankfurt(Main)Hbf to Milano Centrale
Ave. Duration
7h 34m
Frequency
Once daily
Estimated price
$95 - $140
Website
orario.trenitalia.com
Trenitalia Frecce

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Milano Centrale to Roma Termini
Ave. Duration
3h 20m
Frequency
Hourly
Estimated price
$65 - $95
Website
orario.trenitalia.com
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Milano Centrale Station to Roma Termini Station
Ave. Duration
3h 28m
Frequency
Hourly
Estimated price
$40 - $65
Website
italotreno.it
Trenitalia Intercity

The primary train operator in Italy, Trenitalia was created in the year 2000. Trenitalia offers national rail connections in Italy as well as international connections to Austria, France, Germany and Switzerland. The company operates regional and long-distance trains, as well as high-speed trains called Frecce that travel on specialised tracks on speeds of up to 360km/h. Trenitalia tickets are available online, in stations across the country or from many travel agents that offer bookings.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Palermo Centrale
Ave. Duration
11h 39m
Frequency
4 times a day
Estimated price
$80 - $100
Website
orario.trenitalia.com
Train from Milano Centrale to Palermo Centrale
Ave. Duration
20h 46m
Frequency
Once daily
Estimated price
$140 - $190
Website
orario.trenitalia.com
Bus operators
Busitalia Simet S.p.A.
Autoservizi Salemi Srl
Phone
(+39) 0923 98.11.20
Website
autoservizisalemi.it
Bus and ferry from Termoli to Palermo
Ave. Duration
11h 59m
Frequency
Once daily
Estimated price
$65 - $95
Schedules at
autoservizisalemi.it
FlixBus

One of Europe’s leading bus companies, Flixbus serves over 1400 destinations, in 26 countries including Germany, France, Italy, Austria, the Netherlands, Croatia, Spain, and across Scandinavia and central and eastern Europe. Founded in 2012, Flixbus’ extensive network connects cities with approximately 200,000 trips, with buses often departing every 30 minutes. One of the most affordable ways to get around Europe (and expanding soon into the US), a Flixbus journey is cost-effective, well-connected, comfortable and safe.

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Frankfurt, Frankfurt central station to Zurich
Ave. Duration
6h 30m
Frequency
5 times a day
Estimated price
$25 - $45
Website
flixbus.co.uk
Marino Autolinee
Phone
+39 080 3112335
Email
info@marinobus.it
Website
marinobus.it
Bus from Frankfurt to Zurigo
Ave. Duration
7h 35m
Frequency
Once daily
Estimated price
$32
Website
Marino Autolinee
Eurolines CH
Phone
0041 (0) 844 257 224
Website
eurolines.ch
Bus and ferry from Zurich to Palermo
Ave. Duration
23h 35m
Frequency
Twice a week
Estimated price
$130 - $160
Book at
eurolines.ch
Ferry operators

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Frankfurt Airport to Palermo Airport is the direct flight which takes 2h 15m.

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Frankfurt am Main to Sicily bus services, operated by Autoservizi Salemi Srl, arrive at Palermo station.

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Frankfurt am Main to Sicily train services, operated by Trenitalia Intercity, arrive at Palermo Centrale station.

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Lufthansa and Alitalia offer flights from Frankfurt Airport to Palermo Airport.

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Book your Frankfurt am Main to Sicily train tickets online with Loco2, Loco2 and two other operators.

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There are 186+ hotels available in Sicily. Prices start at $40 USD per night.

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The best way to get from Frankfurt am Main to Frankfurt Airport is to train which takes 13m and costs 9€ - 14€.

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