Explore 6 ways to travel

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Catania  •  5 h 12 min

  1. FRA - CTA

$97 - $400

8 alternative options

Fly to Palermo  •  5 h 36 min

  1. FRA - PMO

$104 - $304

Fly to Trapani  •  7 h 16 min

  1. FRA - TPS

$186 - $661

Fly to Comiso  •  8 h 11 min

  1. FRA - CIY

$161 - $766

Train via Roma Termini  •  24 h 1 min

  1. Ece / ...
  2. Fr
  3. Ic

$225 - $448

Drive, ferry  •  25 h 39 min

$213 - $338

Train  •  29 h 49 min

  1. Ece / ...
  2. Icn

$251 - $441

Bus, bus and ferry  •  30 h 26 min

  1. X07 / ...

$156 - $201

Bus  •  32 h 33 min

$139 - $197

What companies run services between Frankfurt am Main, Germany and Sicily, Italy?

Lufthansa, Ryanair and 10 other airlines fly from Frankfurt am Main to Catania every 2 hours. Alternatively, you can take a train from Frankfurt am Main to Palermo via Milano Centrale, Roma Termini, and Palermo Centrale in around 24 h 1 min.

Airlines
Alitalia
Website
alitalia.com
Flights from Frankfurt to Catania via Milan Linate
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$180 - $700
Flights from Frankfurt to Catania via Rome
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$180 - $700
Flights from Frankfurt to Palermo via Milan Linate
Ave. Duration
4 h 26 min
When
Every day
Estimated price
$180 - $500
Flights from Frankfurt to Palermo via Rome
Ave. Duration
4 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$180 - $500
Flights from Frankfurt to Trapani via Milan Linate
Ave. Duration
5 h 35 min
When
Every day
Estimated price
$190 - $1,100
Flights from Frankfurt to Trapani via Rome
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$340 - $1,500
Flights from Frankfurt to Trapani via Milan Linate, Rome
Ave. Duration
6 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$350 - $1,600
Flights from Frankfurt to Trapani via Turin, Rome
Ave. Duration
6 h 5 min
When
Monday to Saturday
Estimated price
$360 - $1,600
Flights from Frankfurt to Trapani via Verona, Rome
Ave. Duration
6 h 15 min
When
Every day
Estimated price
$600 - $900
Ryanair
Website
ryanair.com
Flights from Frankfurt to Catania
Ave. Duration
2 h 30 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$50 - $270
Flights from Frankfurt to Catania via Perugia
Ave. Duration
4 h 30 min
When
Tuesday
Estimated price
$50 - $270
Flights from Frankfurt to Trapani via Prague
Ave. Duration
6 h 30 min
When
Tuesday and Saturday
Estimated price
$110 - $550
Flights from Frankfurt to Comiso via Pisa
Ave. Duration
5 h 35 min
When
Wednesday
Estimated price
$150 - $750
Flights from Frankfurt to Comiso via Milan Malpensa
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$150 - $800
Flights from Frankfurt to Comiso via Rome
Ave. Duration
6 h 10 min
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$550 - $2,500
Lufthansa
Website
lufthansa.com
Flights from Frankfurt to Catania
Ave. Duration
2 h 25 min
When
Every day
Estimated price
$290 - $1,000
Flights from Frankfurt to Catania via Munich
Ave. Duration
4 h 2 min
When
Monday to Saturday
Estimated price
$290 - $1,000
Flights from Frankfurt to Palermo
Ave. Duration
2 h 25 min
When
Saturday and Sunday
Estimated price
$260 - $1,200
Flights from Frankfurt to Palermo via Munich
Ave. Duration
3 h 40 min
When
Monday to Friday
Estimated price
$260 - $1,200
Condor Flugdienst
Website
condor.com
Flights from Frankfurt to Catania
Ave. Duration
2 h 35 min
When
Tuesday, Thursday and Saturday
Estimated price
$210 - $900
Flights from Frankfurt to Palermo
Ave. Duration
2 h 30 min
When
Wednesday and Sunday
Estimated price
$100 - $470
KLM
Website
klm.com
Flights from Frankfurt to Catania via Amsterdam
Ave. Duration
5 h 15 min
When
Saturday and Sunday
Estimated price
$160 - $600
Air France
Website
airfrance.com
Flights from Frankfurt to Catania via Paris CDG
Ave. Duration
5 h 40 min
When
Tuesday, Thursday and Saturday
Estimated price
$310 - $1,000
Brussels Airlines
Website
brusselsairlines.com
Flights from Frankfurt to Comiso via Brussels
Ave. Duration
4 h 20 min
When
Saturday
Estimated price
$350 - $1,400
Air Malta
Website
airmalta.com
Flights from Frankfurt to Comiso via Malta
Ave. Duration
4 h 45 min
When
Wednesday, Friday and Sunday
Estimated price
$600 - $2,700
Train operators
Deutsche Bahn
Phone
+49 0180 6 99 66 33
Website
bahn.com
Train from Frankfurt(Main)Hbf to Milano Centrale
Ave. Duration
7 h 34 min
Frequency
Twice daily
Estimated price
$140 - $250
Website
bahn.de
ItaloTreno
Phone
+39 060708
Website
italotreno.it
Train from Milano Centrale Station to Roma Termini Station
Ave. Duration
2 h 58 min
Frequency
4 times a day
Estimated price
$45 - $65
Website
italotreno.it
Trenitalia Intercity
Phone
+39 06 68475475
Website
trenitalia.com
Train from Roma Termini to Palermo Centrale
Ave. Duration
11 h 39 min
Frequency
5 times a day
Estimated price
$80 - $100
Website
orario.trenitalia.com
Train from Milano Centrale to Palermo Centrale
Ave. Duration
20 h 46 min
Frequency
Twice daily
Estimated price
$150 - $190
Website
orario.trenitalia.com
Bus operators
FlixBus
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Frankfurt, Frankfurt central station to Zurich
Ave. Duration
5 h 15 min
Frequency
4 times a day
Estimated price
$23 - $40
Website
flixbus.co.uk
Eurolines CH
Phone
0041 (0) 844 257 224
Website
eurolines.ch
Bus and ferry from Zurich to Palermo
Ave. Duration
23 h 35 min
Frequency
Twice a week
Estimated price
$130 - $160
Book at
eurolines.ch
Simet SPA
Phone
+39.0983.520315
Email
simetspa@simetspa.it
Website
simetspa.it
Bus from Frankfurt to Cosenza
Ave. Duration
23 h 46 min
Frequency
Once a week
Estimated price
$110 - $170
Schedules at
simetspa.it
Ias Auto Linee
Phone
0983 565635
Email
ias@iasautolinee.it
Website
iasautolinee.com
Bus and ferry from Cosenza to Palermo
Ave. Duration
7 h 18 min
Frequency
Once daily
Estimated price
$20 - $29
Schedules at
iasautolinee.com
Ferry operators

Want to know more about travelling around Italy

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Questions & Answers

The distance between Frankfurt am Main and Sicily is 1459 km.

The cheapest way to get from Frankfurt am Main to Sicily is to bus which costs 110€ - 170€ and takes 32 h 33 min.

The quickest way to get from Frankfurt am Main to Sicily is to fly which takes 5 h 12 min and costs 80€ - 340€.

No, there is no direct train from Frankfurt am Main to Sicily. However, there are services departing from Frankfurt(Main)Hbf and arriving at Palermo Notarbartolo via Milano Centrale, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 24 h 1 min.

No, there is no direct bus from Frankfurt am Main to Sicily. However, there are services departing from Frankfurt, Frankfurt central station and arriving at Piazza Boiardo via Zurich and Stazione Centrale - Pensilina Esterna. The journey, including transfers, takes approximately 30 h 26 min.

It takes approximately 5 h 12 min to get from Frankfurt am Main to Sicily, including transfers.