There are 8 ways to get from Frankfurt Airport (FRA) to Santa Cruz Airport (VVI) by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Santa Cruz  •  15 h 55 min

  1. Fly from Frankfurt (FRA) to Santa Cruz (VVI) FRA - VVI

$600 - $2,500

Cheapest option

Fly to Tarija, bus  •  38 h 15 min

  1. Fly from Frankfurt (FRA) to Tarija (TJA) FRA - TJA
  2. Take the bus from Tarija to Santa Cruz de la Sierra

$508 - $1,205

6 alternative options

Fly to Cochabamba, bus  •  27 h 38 min

  1. Fly from Frankfurt (FRA) to Cochabamba (CBB) FRA - CBB
  2. Take the bus from Cochabamba to Santa Cruz de la Sierra

$623 - $1,475

Fly to Monteagudo, drive  •  28 h 8 min

  1. Fly from Frankfurt (FRA) to Monteagudo (MHW) FRA - MHW
  2. Drive from Monteagudo to Santa Cruz Airport (VVI)

$728 - $2,258

Fly to Trinidad, bus  •  29 h 15 min

  1. Fly from Frankfurt (FRA) to Trinidad (TDD) FRA - TDD
  2. Take the bus from Trinidad to Santa Cruz

$776 - $1,835

Fly to Sucre, bus  •  29 h 24 min

  1. Fly from Frankfurt (FRA) to Sucre (SRE) FRA - SRE
  2. Take the bus from Sucre to Aiquile
  3. Take the bus from Aiquile to Santa Cruz - Tercer Anillo

$1,083 - $4,029

Fly to Oruro, bus  •  36 h 20 min

  1. Fly from Frankfurt (FRA) to Oruro (ORU) FRA - ORU
  2. Take the bus from Oruro to Santa Cruz de la Sierra

$769 - $1,849

Fly to Uyuni, bus  •  41 h 57 min

  1. Fly from Frankfurt (FRA) to Uyuni (UYU) FRA - UYU
  2. Take the bus from Uyuni to Oruro
  3. Take the bus from Oruro to Santa Cruz de la Sierra

$1,140 - $2,719

Questions & Answers

The distance between Frankfurt Airport (FRA) and Santa Cruz Airport (VVI) is 10265 km.

It takes approximately 15 h 55 min to fly from Frankfurt (FRA) to Santa Cruz (VVI), including transfers and time at the airport.

More details

There is no direct flight from Frankfurt Airport to Santa Cruz Airport. The quickest flight takes 16 h 20 min and has one stopover.

Search flights

Santa Cruz Airport (VVI) is 5 h behind Frankfurt Airport (FRA). It is currently 2:58 PM in Frankfurt Airport (FRA) and 8:58 AM in Santa Cruz Airport (VVI).

Copa Airlines, Iberia, Boliviana de Aviación and three other airlines offer flights from Frankfurt Airport to Santa Cruz Airport.

Search flights

There are 230+ hotels available in Santa Cruz Airport (VVI). Prices start at $28 USD per night.

More details

Map of how to get from Frankfurt Airport (FRA) to Santa Cruz Airport (VVI).
Launch map view
  • Distance: 6415.7 miles
  • Duration: 15 h 55 min

What companies run services between Frankfurt Airport (FRA), Germany and Santa Cruz Airport (VVI), Bolivia?

Air Europa, Lufthansa and seven other airlines fly from Frankfurt Airport (FRA) to Santa Cruz Airport (VVI) every 4 hours.

Airlines
Boliviana de Aviación
Website
boa.bo
Flights from Frankfurt to Santa Cruz via Madrid
Ave. Duration
15 h 55 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$550 - $1,400
Flights from Frankfurt to Cochabamba via Madrid
Ave. Duration
16 h 55 min
When
Tuesday
Estimated price
$600 - $1,500
Flights from Frankfurt to Cochabamba via Madrid, Santa Cruz
Ave. Duration
18 h 52 min
When
Every day
Estimated price
$600 - $1,700
Flights from Frankfurt to Cochabamba via Sao Paulo
Ave. Duration
22 h 30 min
When
Monday, Wednesday and Friday
Estimated price
$700 - $3,200
Flights from Frankfurt to Cochabamba via Geneva, Madrid
Ave. Duration
17 h 55 min
When
Tuesday
Estimated price
$600 - $1,500
Flights from Frankfurt to Monteagudo via Madrid, Santa Cruz
Ave. Duration
20 h 42 min
When
Thursday
Estimated price
$700 - $2,300
Flights from Frankfurt to Monteagudo via Bogota, Santa Cruz
Ave. Duration
25 h 30 min
When
Thursday
Estimated price
$850 - $3,900
Flights from Frankfurt to Monteagudo via Sao Paulo, Santa Cruz
Ave. Duration
23 h 20 min
When
Saturday
Estimated price
$850 - $3,900
Flights from Frankfurt to Trinidad via Madrid, Cochabamba
Ave. Duration
23 h 20 min
When
Tuesday
Estimated price
$750 - $1,900
Flights from Frankfurt to Sucre via Madrid, Cochabamba
Ave. Duration
23 h 45 min
When
Tuesday
Estimated price
$490 - $1,200
Flights from Frankfurt to Sucre via Sao Paulo, Cochabamba
Ave. Duration
24 h
When
Monday, Wednesday and Friday
Estimated price
$550 - $2,600
Flights from Frankfurt to Sucre via Madrid, Santa Cruz, Cochabamba
Ave. Duration
21 h 40 min
When
Tuesday, Thursday, Saturday and Sunday
Estimated price
$470 - $1,500
Flights from Frankfurt to Sucre via Madrid, Santa Cruz, La Paz
Ave. Duration
22 h 5 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$500 - $1,300
Flights from Frankfurt to Sucre via Madrid, Cochabamba, Santa Cruz
Ave. Duration
23 h
When
Tuesday
Estimated price
$500 - $1,300
Flights from Frankfurt to Sucre via Madrid, Cochabamba, La Paz
Ave. Duration
23 h 5 min
When
Tuesday
Estimated price
$500 - $1,300
Flights from Frankfurt to Oruro via Madrid, Santa Cruz, Cochabamba
Ave. Duration
20 h
When
Sunday
Estimated price
$750 - $1,800
Flights from Frankfurt to Oruro via Madrid, Cochabamba
Ave. Duration
23 h 15 min
When
Tuesday
Estimated price
$750 - $1,800
Flights from Frankfurt to Oruro via Madrid, Santa Cruz
Ave. Duration
25 h 25 min
When
Friday
Estimated price
$750 - $1,800
Flights from Frankfurt to Oruro via Sao Paulo, Santa Cruz, Cochabamba
Ave. Duration
26 h 55 min
When
Saturday
Estimated price
$850 - $3,900
Flights from Frankfurt to Oruro via Sao Paulo, Santa Cruz
Ave. Duration
22 h 25 min
When
Wednesday
Estimated price
$850 - $3,900
Flights from Frankfurt to Oruro via Bogota, Santa Cruz
Ave. Duration
29 h 5 min
When
Friday
Estimated price
$900 - $4,000
Flights from Frankfurt to Oruro via Miami, Santa Cruz
Ave. Duration
32 h 15 min
When
Friday
Estimated price
$950 - $4,100
Flights from Frankfurt to Tarija via Madrid, Cochabamba
Ave. Duration
23 h 35 min
When
Tuesday
Estimated price
$490 - $1,200
Flights from Frankfurt to Tarija via Madrid, Santa Cruz, Cochabamba
Ave. Duration
21 h 30 min
When
Tuesday, Thursday and Sunday
Estimated price
$470 - $1,500
Flights from Frankfurt to Tarija via Sao Paulo, Santa Cruz
Ave. Duration
26 h 15 min
When
Tuesday, Thursday and Sunday
Estimated price
$550 - $2,500
Flights from Frankfurt to Tarija via Madrid, Santa Cruz, Sucre
Ave. Duration
24 h 35 min
When
Tuesday, Thursday, Saturday and Sunday
Estimated price
$460 - $1,500
Flights from Frankfurt to Uyuni via Madrid, Santa Cruz, La Paz
Ave. Duration
21 h
When
Monday, Wednesday, Friday and Sunday
Estimated price
$1,100 - $2,700
Flights from Frankfurt to Uyuni via Madrid, Cochabamba, La Paz
Ave. Duration
22 h
When
Tuesday
Estimated price
$1,100 - $2,700
Amaszonas
Website
amaszonas.com
Flights from Frankfurt to Trinidad via Madrid, Santa Cruz
Ave. Duration
20 h 2 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$750 - $1,800
Flights from Frankfurt to Trinidad via Bogota, Santa Cruz
Ave. Duration
22 h 40 min
When
Every day
Estimated price
$900 - $4,000
Flights from Frankfurt to Sucre via Madrid, Santa Cruz
Ave. Duration
18 h 45 min
When
Saturday
Estimated price
$460 - $1,500
Flights from Frankfurt to Sucre via Bogota, Santa Cruz
Ave. Duration
23 h 30 min
When
Saturday
Estimated price
$550 - $2,600
Flights from Frankfurt to Uyuni via Madrid, Santa Cruz
Ave. Duration
22 h 17 min
When
Tuesday, Thursday and Sunday
Estimated price
$1,000 - $3,200
Flights from Frankfurt to Uyuni via Bogota, La Paz
Ave. Duration
23 h 30 min
When
Every day
Estimated price
$1,200 - $5,500
Flights from Frankfurt to Uyuni via Bogota, Santa Cruz
Ave. Duration
27 h 5 min
When
Tuesday, Thursday and Sunday
Estimated price
$1,200 - $6,000
Flights from Frankfurt to Uyuni via Panama City, Santa Cruz
Ave. Duration
29 h 50 min
When
Sunday
Estimated price
$1,300 - $6,000
Iberia
Website
iberia.com
Flights from Frankfurt to Santa Cruz via Madrid
Ave. Duration
16 h 57 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$550 - $1,400
Flights from Frankfurt to Cochabamba via Madrid
Ave. Duration
19 h 25 min
When
Tuesday
Estimated price
$600 - $1,500
Flights from Frankfurt to Cochabamba via Madrid, Santa Cruz
Ave. Duration
19 h 22 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$600 - $1,500
Flights from Frankfurt to Cochabamba via Geneva, Madrid
Ave. Duration
17 h 55 min
When
Tuesday
Estimated price
$600 - $1,500
Eco Jet
Website
ecojet.bo
Flights from Frankfurt to Trinidad via Madrid, Santa Cruz
Ave. Duration
19 h 7 min
When
Saturday
Estimated price
$700 - $2,300
Flights from Frankfurt to Trinidad via Bogota, La Paz
Ave. Duration
23 h 55 min
When
Saturday
Estimated price
$850 - $3,900
Flights from Frankfurt to Tarija via Madrid, Santa Cruz
Ave. Duration
18 h 37 min
When
Tuesday, Thursday and Sunday
Estimated price
$460 - $1,500
Flights from Frankfurt to Tarija via Bogota, Santa Cruz
Ave. Duration
23 h 25 min
When
Tuesday, Thursday and Sunday
Estimated price
$550 - $2,600
Air Europa
Website
aireuropa.com
Flights from Frankfurt to Santa Cruz via Madrid
Ave. Duration
16 h 17 min
When
Tuesday, Thursday, Saturday and Sunday
Estimated price
$800 - $6,500
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Frankfurt to Santa Cruz via Bogota
Ave. Duration
17 h 19 min
When
Every day
Estimated price
$650 - $3,000
Flights from Frankfurt to Santa Cruz via Madrid, Bogota
Ave. Duration
21 h 14 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$1,200 - $3,600
Copa Airlines
Website
copaair.com
Flights from Frankfurt to Santa Cruz via Panama City
Ave. Duration
22 h 15 min
When
Monday, Wednesday, Friday and Sunday
Estimated price
$650 - $3,000
Bus operators
Trans Salvador
Phone
+56 58 222 8547
Email
central@trans-salvador.com
Website
trans-salvador.com
Bus from Cochabamba to Santa Cruz de la Sierra
Ave. Duration
8 h 30 min
Frequency
3 times a week
Estimated price
$14 - $24
Schedules at
trans-salvador.com
Book at
ticketsbolivia.com.bo
Semi Bed
$14 - $19
Premium
$19 - $24
Bus from Oruro to Santa Cruz de la Sierra
Ave. Duration
14 h 30 min
Frequency
3 times a week
Estimated price
$19 - $60
Schedules at
trans-salvador.com
Book at
ticketsbolivia.com.bo
Semi Bed
$19 - $25
Premium
$26 - $35
Flota Bolivar
Phone
+591 2 2281973 La Paz / 4 4221819 Cochabamba / 3 3625458 Santa Cruz / 4 6453849 Sucre / 4 6830856 Yacuiba
Website
facebook.com
Bus from Trinidad to Santa Cruz
Ave. Duration
8 h 30 min
Frequency
Twice daily
Estimated price
$13 - $21
Schedules at
facebook.com
Trans Cotoca
Phone
+591 76340023 Santa Cruz / 77666566 Yacuiba / 76340027 Trinidad / 76240024 Cochabamba
Website
facebook.com
Bus from Trinidad to Santa Cruz de la Sierra - Terminal Bimodal
Ave. Duration
9 h
Frequency
Twice daily
Estimated price
$19
Schedules at
facebook.com
Trans Copacabana SA
Phone
Cochabamba: +(591)44591818, +(591)72244625
Email
info@transcopacabanasa.com.bo
Website
transcopacabanasa.com.bo
Bus from Trinidad to Santa Cruz de la Sierra - Terminal bimodal
Ave. Duration
10 h
Frequency
Twice daily
Estimated price
$9 - $18
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$9 - $13
2nd Class
$13 - $18
Bus from Sucre to Aiquile
Ave. Duration
1 h 30 min
Frequency
Twice daily
Estimated price
$4 - $7
Schedules at
transcopacabanasa.com.bo
Book at
ticketsbolivia.com.bo
3rd Class
$4 - $6
2nd Class
$5 - $7
Transporte Señor de Burgos
Phone
+591 4 4303530 Cochabamba / 4 4342227 Mizque
Website
facebook.com
Bus from Aiquile to Santa Cruz - Tercer Anillo
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$6
Schedules at
facebook.com
Autotransportes Tupiza
Phone
+591 68421233 Tupiza / 3 3311649 Santa Cruz / 2 6243044 Potosí
Website
facebook.com
Bus from Tarija to Santa Cruz de la Sierra
Ave. Duration
18 h
Frequency
Twice daily
Estimated price
$14 - $18
Schedules at
facebook.com
Transporte Platinum
Phone
+591 4 6662724 Tarija / 2 2284261 La Paz / 3 3646948 Santa Cruz / 4 71865640 Cochabamba
Website
facebook.com
Bus from Tarija to Santa Cruz de la Sierra
Ave. Duration
18 h
Frequency
Once daily
Estimated price
$29
Schedules at
facebook.com
Trans Azul
Phone
+591 5254060
Website
facebook.com
Bus from Uyuni to Oruro
Ave. Duration
5 h
Frequency
Once a week
Estimated price
$5 - $7
Schedules at
ticketsbolivia.com.bo
Book at
ticketsbolivia.com.bo

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Train travel in Spain: A guide to Renfe, How to get from London City Airport into central London and Travelling around the UAE - to help you get the most out of your next trip.