There are 4 ways to get from Frankfort to St. Louis by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Lexington  •  4 h 57 min

  1. Fly from Lexington (LEX) to St. Louis (STL) LEX - STL

$262 - $1,034

Cheapest option

Bus  •  9 h 31 min

  1. Take the bus from Frankfort, KY to Evansville Lexington
  2. Take the bus from Evansville, In to St Louis, Mo 4702 / ...

$79 - $135

2 alternative options

Bus to Owensboro, fly  •  7 h 12 min

  1. Take the bus from Frankfort, KY to Owensboro, KY
  2. Fly from Owensboro (OWB) to St. Louis (STL) OWB - STL

$94 - $147

Drive  •  5 h 11 min

  1. Drive from Frankfort to St. Louis 313.6 miles

$30 - $45

Questions & Answers

The distance between Frankfort and St. Louis is 291 miles. The road distance is 313.6 miles.

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The best way to get from Frankfort to St. Louis without a car is to bus which takes 9 h 31 min and costs .

More details

It takes approximately 4 h 57 min to get from Frankfort to St. Louis, including transfers.

More details

The best way to get from Frankfort to St. Louis is to fly which takes 4 h 57 min and costs . Alternatively, you can bus, which costs and takes 9 h 31 min.

Mode details

There is no direct flight from Lexington Airport to St. Louis Airport. The quickest flight takes 3 h 44 min and has one stopover.

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St. Louis is 1 h behind Frankfort. It is currently 3:58 PM in Frankfort and 2:58 PM in St. Louis.

Yes, the driving distance between Frankfort to St. Louis is 314 miles. It takes approximately 5 h 11 min to drive from Frankfort to St. Louis.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Lexington Airport to St. Louis Airport.

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There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

More details

The best way to get from Frankfort to Lexington Airport is to taxi which takes 32 min and costs .

More details

Map of how to get from Frankfort to St. Louis.
Launch map view
  • Distance: 291.4 miles
  • Duration: 4 h 57 min

What companies run services between Frankfort, KY, USA and St. Louis, MO, USA?

American Airlines, Delta and United Airlines fly from Frankfort to St. Louis hourly. Alternatively, you can take a bus from Frankfort to St. Louis via Frankfort, KY, Evansville, and Evansville, In in around 9 h 31 min.

Airlines
American Airlines
Website
aa.com
Flights from Lexington to St. Louis via Chicago O'Hare
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$190 - $950
Flights from Lexington to St. Louis via Charlotte
Ave. Duration
4 h 42 min
When
Every day
Estimated price
$210 - $950
Flights from Lexington to St. Louis via Philadelphia
Ave. Duration
5 h 40 min
When
Every day
Estimated price
$250 - $1,100
Flights from Lexington to St. Louis via Dallas/Ft.Worth
Ave. Duration
6 h 4 min
When
Every day
Estimated price
$250 - $1,100
Flights from Owensboro to St. Louis
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$24 - $110
Delta
Website
delta.com
Flights from Lexington to St. Louis via Detroit
Ave. Duration
4 h 40 min
When
Every day
Estimated price
$180 - $950
Flights from Lexington to St. Louis via Atlanta
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$190 - $950
United Airlines
Website
united.com
Flights from Lexington to St. Louis via Chicago O'Hare
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$200 - $950
Flights from Lexington to St. Louis via Houston
Ave. Duration
5 h 55 min
When
Every day
Estimated price
$270 - $1,200
Cape Air
Website
capeair.com
Flights from Owensboro to St. Louis
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$24 - $110
Bus operators
Hoosier Ride
Phone
800-544-2383
Website
hoosierride.com
Bus from Frankfort, KY to Owensboro, KY
Ave. Duration
4 h
Frequency
Twice daily
Estimated price
$35 - $50
Book at
hoosierride.com
Bus from Frankfort, KY to Evansville
Ave. Duration
4 h 55 min
Frequency
Twice daily
Estimated price
$40 - $60
Book at
hoosierride.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Evansville, In to St Louis, Mo
Ave. Duration
3 h 55 min
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55

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