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There are 4 ways to get from Frankfort to St. Louis by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  9h 22m

  1. Take the bus from Frankfort, KY to Evansville Lexington
  2. Take the bus from Evansville, In to St Louis, Mo 1162 / ...

$79 - $135

3 alternative options

Drive  •  5h 11m

  1. Drive from Frankfort to St. Louis 313.6 miles

$30 - $45

Bus to Owensboro, fly  •  7h 7m

  1. Take the bus from Frankfort, KY to Owensboro, KY
  2. Fly from Owensboro (OWB) to St. Louis (STL) OWB - STL

$94 - $147

Bus, bus to Covington, fly  •  7h 16m

  1. Take the bus from Frankfort, KY to Lexington, KY
  2. Take the bus from Lexington, Ky to Cincinnati, Oh
  3. Fly from Covington (CVG) to St. Louis (STL) CVG - STL

$168 - $436

Questions & Answers

The cheapest way to get from Frankfort to St. Louis is to drive which costs $30 - $45 and takes 5h 11m.

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The quickest way to get from Frankfort to St. Louis is to drive which costs $30 - $45 and takes 5h 11m.

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The distance between Frankfort and St. Louis is 291 miles. The road distance is 313.6 miles.

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The best way to get from Frankfort to St. Louis without a car is to bus which takes 9h 22m and costs $75 - $140.

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It takes approximately 9h 22m to get from Frankfort to St. Louis, including transfers.

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The quickest flight from Owensboro Airport to St. Louis Airport is the direct flight which takes 1h 17m.

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St. Louis is 1h behind Frankfort. It is currently 12:06 AM in Frankfort and 11:06 PM in St. Louis.

Yes, the driving distance between Frankfort to St. Louis is 314 miles. It takes approximately 5h 11m to drive from Frankfort to St. Louis.

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Cape Air offers flights from Owensboro Airport to St. Louis Airport.

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There are 200+ hotels available in St. Louis. Prices start at $65 USD per night.

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Map of how to get from Frankfort to St. Louis.
Launch map view
  • Distance: 291.4 miles
  • Duration: 9h 22m

What companies run services between Frankfort, KY, USA and St. Louis, MO, USA?

You can take a bus from Frankfort to St. Louis via Frankfort, KY, Evansville, and Evansville, In in around 9h 22m.

Airlines
Cape Air
Website
capeair.com
Flights from Owensboro to St. Louis
Ave. Duration
1h 17m
When
Every day
Estimated price
$24 - $110
Southwest Airlines
Website
southwest.com
Flights from Covington to St. Louis via Chicago Midway
Ave. Duration
3h 31m
When
Every day
Estimated price
$190 - $850
Delta
Website
delta.com
Flights from Covington to St. Louis
Ave. Duration
1h 22m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $850
GoJet Airlines
Website
gojetairlines.com
Flights from Covington to St. Louis
Ave. Duration
1h 22m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$60 - $470
Bus operators
Hoosier Ride
Phone
800-544-2383
Website
hoosierride.com
Bus from Frankfort, KY to Evansville
Ave. Duration
4h 55m
Frequency
Twice daily
Estimated price
$40 - $60
Book at
hoosierride.com
Bus from Frankfort, KY to Owensboro, KY
Ave. Duration
4h
Frequency
Twice daily
Estimated price
$35 - $50
Book at
hoosierride.com
Bus from Frankfort, KY to Lexington, KY
Ave. Duration
35m
Frequency
5 times a day
Estimated price
$12 - $16
Book at
hoosierride.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Evansville, In to St Louis, Mo
Ave. Duration
3h 20m
Frequency
Twice daily
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Lexington, Ky to Cincinnati, Oh
Ave. Duration
1h 25m
Frequency
4 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35

Want to know more about travelling around United States

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