There are 10 ways to get from Framingham to Chicago by plane, train (Amtrak), bus (Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Boston Logan Airport to Chicago Midway International Airport
best- Fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW)plane BOS - MDW
4h 55m$101–484Train to Theodore Francis Green State Airport, fly to Chicago O'Hare International Airport
cheapest- Take the train from Back Bay to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Chicago O'Hare International Airport (ORD)plane PVD - ORD
8h 4m$90–420Train (Amtrak)
- Take the train from Framingham Amtrak to Chicago Union Stationtrain Lake Shore Limited
21h 47m$550–850Bus (Flixbus)
- Take the bus from Boston to New York Midtownbus FlixBus 2610 / ...
- Take the bus from New York Midtown to Chicago Bus Stationbus FlixBus N2640 / ...
27h 32m$184–296Drive 961.8 mi
- Drive from Framingham to Chicagocar 961.8 mi
16h 28m$176–254Fly Boston Logan Airport to Chicago O'Hare International Airport
- Fly from Boston Logan Airport (BOS) to Chicago O'Hare International Airport (ORD)plane BOS - ORD
5h 17m$611–1,014Bus to Manchester Airport, fly to Chicago Midway International Airport
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Chicago Midway International Airport (MDW)plane MHT - MDW
7h 7m$95–449Train to Theodore Francis Green State Airport, fly to Chicago Midway International Airport
- Take the train from Back Bay to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Chicago Midway International Airport (MDW)plane PVD - MDW
7h 39m$110–530Train to Bradley International Airport, fly to Chicago Midway International Airport
- Take the train from Framingham Amtrak to Springfieldtrain
- Fly from Bradley International Airport (BDL) to Chicago Midway International Airport (MDW)plane BDL - MDW
7h 46m$139–545Fly Boston Logan Airport to General Mitchell International Airport, train
- Fly from Boston Logan Airport (BOS) to General Mitchell International Airport (MKE)plane BOS - MKE
- Take the train from Milwaukee to Chicago Union Stationtrain
7h 19m$706–1,998
Framingham to Chicago by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Framingham to Chicago is to drive which costs $170 - $260 and takes 16h 28m.
The fastest way to get from Framingham to Chicago is to fly which takes 4h 55m and costs $100 - $490.
No, there is no direct bus from Framingham to Chicago station. However, there are services departing from Framingham and arriving at Chicago Bus Station via Boston and New York Midtown. The journey, including transfers, takes approximately 27h 32m.
Yes, there is a direct train departing from Framingham Amtrak and arriving at Chicago Union Station station. Services depart once daily, and operate every day. The journey takes approximately 21h 47m.
The distance between Framingham and Chicago is 896 miles. The road distance is 967.4 miles.
The best way to get from Framingham to Chicago without a car is to train which takes 21h 47m and costs $550 - $850.
It takes approximately 4h 55m to get from Framingham to Chicago, including transfers.
Framingham to Chicago bus services, operated by Flixbus USA, depart from Boston station.
Framingham to Chicago train services, operated by Amtrak, depart from Framingham Amtrak station.
The best way to get from Framingham to Chicago is to fly which takes 4h 55m and costs $100 - $490. Alternatively, you can train, which costs $550 - $850 and takes 21h 47m, you could also bus, which costs $180 - $300 and takes 27h 32m.
What companies run services between Framingham, MA, USA and Chicago, IL, USA?
Southwest Airlines and Delta fly from Boston Logan Airport (BOS) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, Amtrak operates a train from Framingham Amtrak to Chicago Union Station once daily. Tickets cost $550–850 and the journey takes 21h 47m.
- Website
- southwest.com
Flights from Boston Logan Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $90–470
Flights from Manchester Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $80–420
Flights from Manchester Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $90–440
Flights from Manchester Airport to Chicago Midway International Airport via Nashville
- Ave. Duration
- 5h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–500
Flights from Theodore Francis Green State Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $95–500
Flights from Theodore Francis Green State Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–550
Flights from Bradley International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $85–460
Flights from Bradley International Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 30m
- When
- Tuesday to Friday
- Estimated price
- $95–480
Flights from Boston Logan Airport to General Mitchell International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $140–750
Flights from Boston Logan Airport to General Mitchell International Airport via Baltimore
- Ave. Duration
- 4h 45m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $150–750
- Website
- united.com
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- $70–370
Flights from Theodore Francis Green State Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- $75–390
Flights from Theodore Francis Green State Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 5h 10m
- When
- Wednesday, Thursday, Sunday, Monday, Tuesday, and Friday
- Estimated price
- $80–410
Flights from Boston Logan Airport to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Boston Logan Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $90–470
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $70–370
Flights from Theodore Francis Green State Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $95–500
Flights from Bradley International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $85–460
Flights from Theodore Francis Green State Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $75–390
Flights from Boston Logan Airport to General Mitchell International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $130–700
Flights from Boston Logan Airport to General Mitchell International Airport via Detroit
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Boston Logan Airport to General Mitchell International Airport via New York La Guardia
- Ave. Duration
- 4h 56m
- When
- Monday to Friday
- Estimated price
- $140–700
- Website
- aa.com
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- $70–370
Flights from Theodore Francis Green State Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 56m
- When
- Every day
- Estimated price
- $75–390
Flights from Theodore Francis Green State Airport to Chicago O'Hare International Airport via Philadelphia
- Ave. Duration
- 5h 38m
- When
- Tuesday to Friday
- Estimated price
- $80–400
- Website
- jetblue.com
Flights from Boston Logan Airport to Chicago O'Hare International Airport
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- $70–370
Flights from Boston Logan Airport to General Mitchell International Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $130–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Framingham Amtrak to Chicago Union Station
- Ave. Duration
- 21h 47m
- Frequency
- Once daily
- Estimated price
- $550–850
- Website
- Amtrak
Train from Framingham Amtrak to Springfield
- Ave. Duration
- 1h 56m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Back Bay to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from Back Bay to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to New York Midtown
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Bus from New York Midtown to Chicago Bus Station
- Ave. Duration
- 20h 25m
- Frequency
- Twice daily
- Estimated price
- $150–240
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
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Booking & Getting There
Framingham to Chicago bus services, operated by Flixbus USA, arrive at New York Midtown station.
Chicago is 1h behind Framingham. It is currently 7:38 AM in Framingham and 6:38 AM in Chicago.
Framingham to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Framingham to Chicago is 967 miles. It takes approximately 16h 28m to drive from Framingham to Chicago.
Book your Framingham to Chicago train tickets online with Omio.
Book your Framingham to Chicago bus tickets online with Omio and FlixBus.
There are 1130+ hotels available in Chicago.











