There are 5 ways to get from Fort Wayne to St. Louis by plane, bus (Greyhound), bus, train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Fort Wayne International Airport (FWA) to Lambert–St. Louis International Airport (STL)FWA - STL
4h 51m$125–597Bus
cheapest- Take the bus from Fort Wayne, IN to Indianapolis, INDetroit
- Take the bus from Indianapolis Union Station to St Louis Bus StationGreyhound US0421
8h 32m$48–151Bus, train
- Take the bus from Fort Wayne, IN to ChicagoColumbus / ...
- Take the train from Chicago Union Station to St. LouisLincoln Service / ...
11h 7m$58–276Drive 366 mi
- Drive from Fort Wayne to St. Louis366 mi
6h 5m$67–97Bus via Chicago
- Take the bus from Fort Wayne, IN to ChicagoColumbus / ...
- Take the bus from Chicago Bus Station to St Louis Bus StationFlixBus N2521 / ...
12h 22m$53–131
Fort Wayne to St. Louis by bus
Questions & Answers
The cheapest way to get from Fort Wayne to St. Louis is to bus which costs $45 - $160 and takes 8h 32m.
The fastest way to get from Fort Wayne to St. Louis is to fly which takes 4h 51m and costs $120 - $600.
No, there is no direct bus from Fort Wayne to St. Louis station. However, there are services departing from Wal-Mart and arriving at St Louis Bus Station via Fort Wayne, IN and Indianapolis Union Station. The journey, including transfers, takes approximately 8h 32m.
The distance between Fort Wayne and St. Louis is 344 miles. The road distance is 368.1 miles.
The best way to get from Fort Wayne to St. Louis without a car is to bus which takes 8h 32m and costs $45 - $160.
It takes approximately 4h 51m to get from Fort Wayne to St. Louis, including transfers.
Fort Wayne to St. Louis bus services, operated by Barons Bus, depart from Fort Wayne, IN station.
The best way to get from Fort Wayne to St. Louis is to fly which takes 4h 51m and costs $120 - $600. Alternatively, you can bus, which costs $45 - $160 and takes 8h 32m.
Fort Wayne to St. Louis bus services, operated by Barons Bus, arrive at Indianapolis, IN station.
St. Louis is 1h behind Fort Wayne. It is currently 8:05 AM in Fort Wayne and 7:05 AM in St. Louis.
What companies run services between Fort Wayne, IN, USA and St. Louis, MO, USA?
Delta, United Airlines, and American Airlines fly from Fort Wayne International Airport (FWA) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Wal-Mart to St Louis Bus Station via Fort Wayne, IN and Indianapolis Union Station in around 8h 32m.
- Website
- aa.com
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $85–550
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 36m
- When
- Every day
- Estimated price
- $170–800
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $95–550
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $130–700
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $130–700
- Website
- united.com
Flights from Fort Wayne International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $85–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $40–220
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Fort Wayne, IN to Indianapolis, IN
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- https://baronsbus.com
Bus from Fort Wayne, IN to Chicago
- Ave. Duration
- 3h 50m
- Frequency
- Twice daily
- Estimated price
- $17–55
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $35–100
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–75
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Fort Wayne to St. Louis is 368 miles. It takes approximately 6h 5m to drive from Fort Wayne to St. Louis.
There are 449+ hotels available in St. Louis.