• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 7 ways to get from Fort Wayne to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Greenville/Spartanburg  •  4h 23m

  1. Fly from Fort Wayne (FWA) to Greenville/Spartanburg (GSP) FWA - GSP

$318 - $1,390

Cheapest option

Bus via Ft Wayne, IN  •  24h 2m

  1. Take the bus from Ft Wayne, IN to Columbus, OH
  2. Take the bus from Columbus, Oh to Columbia, Sc
  3. Take the bus from Columbia, SC to Florence, SC

$97 - $230

5 alternative options

Fly to Columbia  •  6h 14m

  1. Fly from Fort Wayne (FWA) to Columbia (CAE) FWA - CAE

$350 - $1,647

Fly to Charlotte, bus  •  5h 3m

  1. Fly from Fort Wayne (FWA) to Charlotte (CLT) FWA - CLT
  2. Take the bus from Transit Center- Bay X to White Street Park and Ride

$334 - $1,253

Bus  •  24h 9m

  1. Take the bus from Fort Wayne, IN to Columbus, OH
  2. Take the bus from Columbus, Oh to Columbia, Sc
  3. Take the bus from Columbia, SC to Florence, SC

$97 - $220

Bus, train  •  28h 42m

  1. Take the bus from Ft Wayne, IN to Elkhart, IN
  2. Take the train from Elkhart Amtrak Station to Washington Union Station
  3. Take the train from Washington Union Station to Florence Amtrak Station

$182 - $479

Drive  •  12h 54m

  1. Drive from Fort Wayne to Florence 693.6 miles

$65 - $100

Questions & Answers

The cheapest way to get from Fort Wayne to South Carolina is to drive which costs $65 - $100 and takes 12h 54m.

More details

The quickest way to get from Fort Wayne to South Carolina is to fly which costs $310 - $1,400 and takes 4h 23m.

More details

No, there is no direct bus from Fort Wayne to South Carolina. However, there are services departing from Coldwater Rd. at Wal-Mart Entrance and arriving at Florence, SC via Ft Wayne, IN, Columbus, Oh and Columbia, SC. The journey, including transfers, takes approximately 24h 2m.

More details

The distance between Fort Wayne and South Carolina is 578 miles. The road distance is 693.6 miles.

Get driving directions

The best way to get from Fort Wayne to South Carolina without a car is to bus which takes 24h 2m and costs $95 - $230.

More details

It takes approximately 4h 23m to get from Fort Wayne to South Carolina, including transfers.

More details

Fort Wayne to South Carolina bus services, operated by Hoosier Ride, depart from Ft Wayne, IN station.

More details

The best way to get from Fort Wayne to South Carolina is to fly which takes 4h 23m and costs $310 - $1,400. Alternatively, you can bus, which costs $95 - $230 and takes 24h 2m.

Mode details

There is no direct flight from Fort Wayne Airport to Greenville/Spartanburg Airport. The quickest flight takes 3h 47m and has one stopover.

Search flights

Fort Wayne to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

More details

Map of how to get from Fort Wayne to South Carolina.
Launch map view
  • Distance: 578.3 miles
  • Duration: 4h 23m

What companies run services between Fort Wayne, IN, USA and South Carolina, USA?

American Airlines, Delta and United Airlines fly from Fort Wayne to Greenville hourly. Alternatively, you can take a bus from Fort Wayne to Florence via Central Station, Ft Wayne, IN, Columbus, OH, Columbus, Oh, Columbia, Sc, and Columbia, SC in around 24h 2m.

Airlines
American Airlines
Website
aa.com
Flights from Fort Wayne to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
5h 11m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,300
Flights from Fort Wayne to Greenville/Spartanburg via Charlotte
Ave. Duration
4h 8m
When
Every day
Estimated price
$260 - $1,300
Flights from Fort Wayne to Greenville/Spartanburg via Philadelphia
Ave. Duration
6h 9m
When
Every day
Estimated price
$310 - $1,400
Flights from Fort Wayne to Greenville/Spartanburg via Dallas/Ft.Worth
Ave. Duration
8h 13m
When
Every day
Estimated price
$390 - $1,600
Flights from Fort Wayne to Columbia via Charlotte
Ave. Duration
5h 6m
When
Every day
Estimated price
$310 - $1,500
Flights from Fort Wayne to Columbia via Philadelphia
Ave. Duration
4h 57m
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$380 - $1,700
Flights from Fort Wayne to Columbia via Dallas/Ft.Worth
Ave. Duration
8h 4m
When
Every day
Estimated price
$470 - $1,900
Flights from Fort Wayne to Columbia via Chicago O'Hare, Charlotte
Ave. Duration
6h 30m
When
Every day
Estimated price
$350 - $1,600
Flights from Fort Wayne to Charlotte
Ave. Duration
1h 52m
When
Every day
Estimated price
$410 - $2,600
Flights from Fort Wayne to Charlotte via Chicago O'Hare
Ave. Duration
4h 22m
When
Every day
Estimated price
$410 - $2,600
Delta
Website
delta.com
Flights from Fort Wayne to Greenville/Spartanburg via Atlanta
Ave. Duration
5h 54m
When
Every day
Estimated price
$250 - $1,300
Flights from Fort Wayne to Greenville/Spartanburg via Detroit
Ave. Duration
5h 46m
When
Every day
Estimated price
$250 - $1,300
Flights from Fort Wayne to Columbia via Atlanta
Ave. Duration
5h 33m
When
Every day
Estimated price
$310 - $1,600
Flights from Fort Wayne to Charlotte via Detroit
Ave. Duration
4h 25m
When
Saturday
Estimated price
$420 - $2,300
United Airlines
Website
united.com
Flights from Fort Wayne to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
7h 15m
When
Every day
Estimated price
$300 - $1,400
Flights from Fort Wayne to Columbia via Chicago O'Hare
Ave. Duration
7h 31m
When
Every day
Estimated price
$360 - $1,700
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Elkhart Amtrak Station to Washington Union Station
Ave. Duration
15h 36m
Frequency
Once daily
Estimated price
$95 - $270
Website
amtrak.com
Coach Seat
$95 - $150
Flexi Coach Seat
$170 - $250
Business Coach Seat
$190 - $270
Room
$390 - $550
Train from Washington Union Station to Florence Amtrak Station
Ave. Duration
7h 40m
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1h 12m
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Hoosier Ride
Phone
800-544-2383
Website
hoosierride.com
Bus from Ft Wayne, IN to Columbus, OH
Ave. Duration
4h
Frequency
Twice daily
Estimated price
$45 - $60
Book at
hoosierride.com
Bus from Ft Wayne, IN to Elkhart, IN
Ave. Duration
1h 50m
Frequency
Once daily
Estimated price
$21 - $28
Book at
hoosierride.com
Barons Bus
Phone
+1 888-378-3823
Website
baronsbus.com
Bus from Fort Wayne, IN to Columbus, OH
Ave. Duration
3h 30m
Frequency
Once daily
Estimated price
$22 - $40
Book at
baronsbus.com
Bus from Fort Wayne, IN to Columbus, OH
Ave. Duration
4h 20m
Frequency
Once daily
Estimated price
$22 - $50
Book at
baronsbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to Columbia, Sc
Ave. Duration
15h 5m
Frequency
Every 4 hours
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $95
Flexible
$100 - $140

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Fort Wayne to South Carolina is 694 miles. It takes approximately 12h 54m to drive from Fort Wayne to South Carolina.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Fort Wayne Airport to Greenville/Spartanburg Airport.

Search flights

There are 19+ hotels available in South Carolina. Prices start at $49 USD per night.

More details

The best way to get from Fort Wayne to Fort Wayne Airport is to taxi which takes 19m and costs $35 - $45.

More details