There are 5 ways to get from Fort Wayne to Middlesboro by plane, car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, drive
best- Fly from Fort Wayne International Airport (FWA) to Mcghee Tyson Airport (TYS)plane FWA - TYS
- Drive from Mcghee Tyson Airport (TYS) to Middlesborocar
6h 4m$250–1,264Bus, drive
cheapest- Take the bus from Fort Wayne, IN to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Londonbus
- Drive from London to Middlesborocar
11h 38m$57–140Drive 359.3 mi
- Drive from Fort Wayne to Middlesborocar 359.3 mi
7h 39m$66–95Bus, drive via Reading
- Take the bus from Fort Wayne, IN to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Cincinnati Bus Stationbus
- Take the bus from Cincinnati Bus Station to Londonbus
- Drive from London to Middlesborocar
11h 50m$59–136Bus, drive via Reading #2
- Take the bus from Fort Wayne, IN to Greyhound Station Cincinnatibus
- Take the bus from Cincinnati Bus Station to Londonbus
- Drive from London to Middlesborocar
12h 53m$64–140
Fort Wayne International Airport (FWA) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Fort Wayne to Middlesboro is to drive which costs $65 - $95 and takes 7h 39m.
The fastest way to get from Fort Wayne to Middlesboro is to fly and drive which takes 6h 4m and costs $250 - $1,300.
The distance between Fort Wayne and Middlesboro is 452 miles. The road distance is 361.4 miles.
It takes approximately 6h 4m to get from Fort Wayne to Middlesboro, including transfers.
Yes, the driving distance between Fort Wayne to Middlesboro is 361 miles. It takes approximately 7h 39m to drive from Fort Wayne to Middlesboro.
There are 19+ hotels available in Middlesboro.
What companies run services between Fort Wayne, IN, USA and Middlesboro, KY, USA?
There is no direct connection from Fort Wayne to Middlesboro. However, you can take the taxi to Fort Wayne International Airport (FWA) airport, fly to Mcghee Tyson Airport (TYS), then drive to Middlesboro. Alternatively, you can take a bus from Wal-Mart to Middlesboro via Fort Wayne, IN, Dayton Trotwood Bus Station, and London in around 11h 38m.
- Website
- united.com
Flights from Fort Wayne International Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $210–1,300
- Website
- aa.com
Flights from Fort Wayne International Airport to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $210–1,300
Flights from Fort Wayne International Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $210–1,300
- Website
- delta.com
Flights from Fort Wayne International Airport to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $220–1,300
Flights from Fort Wayne International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 7h 40m
- When
- Every day
- Estimated price
- $200–1,200
- Website
- allegiantair.com
Flights from Fort Wayne International Airport to Mcghee Tyson Airport via Orlando Sanford
- Ave. Duration
- 5h 21m
- When
- Thursday
- Estimated price
- $370–1,800
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Fort Wayne, IN to Dayton Trotwood Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- https://baronsbus.com
Bus from Fort Wayne, IN to Greyhound Station Cincinnati
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $25–70
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Dayton Trotwood Bus Station to London
- Ave. Duration
- 5h 15m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Dayton Trotwood Bus Station to Cincinnati Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- https://www.greyhound.com/
Bus from Cincinnati Bus Station to London
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $29–55
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide






