There are 5 ways to get from Fort Wayne to Great Smoky Mountains by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, drive  •  5 h 45 min

  1. Fly from Fort Wayne (FWA) to Knoxville (TYS) FWA - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$314 - $1,555

Cheapest option

Bus, drive via Ft Wayne, IN  •  22 h 40 min

  1. Take the bus from Ft Wayne, IN to Columbus, OH
  2. Take the bus from Columbus, Oh to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains

$90 - $233

3 alternative options

Fly to Asheville, drive  •  6 h 9 min

  1. Fly from Fort Wayne (FWA) to Asheville (AVL) FWA - AVL
  2. Drive from Asheville to Great Smoky Mountains

$356 - $1,457

Bus, drive  •  22 h 47 min

  1. Take the bus from Fort Wayne, IN to Columbus, OH
  2. Take the bus from Columbus, Oh to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains

$90 - $223

Drive  •  9 h 27 min

  1. Drive from Fort Wayne to Great Smoky Mountains 510.9 miles

$50 - $75

Questions & Answers

The distance between Fort Wayne and Great Smoky Mountains is 395 miles. The road distance is 510.9 miles.

Get driving directions

It takes approximately 5 h 45 min to get from Fort Wayne to Great Smoky Mountains, including transfers.

More details

There is no direct flight from Fort Wayne Airport to Knoxville Airport. The quickest flight takes 3 h 28 min and has one stopover.

Search flights

Yes, the driving distance between Fort Wayne to Great Smoky Mountains is 511 miles. It takes approximately 9 h 27 min to drive from Fort Wayne to Great Smoky Mountains.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Fort Wayne Airport to Knoxville Airport.

Search flights

There are 1425+ hotels available in Great Smoky Mountains. Prices start at $67 USD per night.

More details

The best way to get from Fort Wayne to Fort Wayne Airport is to taxi which takes 19 min and costs .

More details

Map of how to get from Fort Wayne to Great Smoky Mountains.
Launch map view
  • Distance: 395.5 miles
  • Duration: 5 h 45 min

What companies run services between Fort Wayne, IN, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Fort Wayne to Great Smoky Mountains. However, you can take the taxi to Fort Wayne airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the taxi to Fort Wayne airport, fly to Asheville, then take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Fort Wayne to Knoxville via Detroit
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$270 - $1,500
Flights from Fort Wayne to Knoxville via Atlanta
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$290 - $1,500
Flights from Fort Wayne to Asheville via Atlanta
Ave. Duration
4 h 46 min
When
Every day
Estimated price
$290 - $1,500
Flights from Fort Wayne to Asheville via Detroit, Atlanta
Ave. Duration
7 h 10 min
When
Monday, Tuesday, Wednesday and Thursday
Estimated price
$320 - $1,600
American Airlines
Website
aa.com
Flights from Fort Wayne to Knoxville via Philadelphia
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$360 - $1,600
Flights from Fort Wayne to Knoxville via Charlotte
Ave. Duration
5 h 56 min
When
Every day
Estimated price
$300 - $1,500
Flights from Fort Wayne to Knoxville via Chicago O'Hare
Ave. Duration
5 h 15 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,500
Flights from Fort Wayne to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 43 min
When
Every day
Estimated price
$430 - $1,700
Flights from Fort Wayne to Asheville via Charlotte
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$300 - $1,500
Flights from Fort Wayne to Asheville via Chicago O'Hare, Charlotte
Ave. Duration
7 h 9 min
When
Every day
Estimated price
$340 - $1,600
United Airlines
Website
united.com
Flights from Fort Wayne to Knoxville via Chicago O'Hare
Ave. Duration
5 h 50 min
When
Every day
Estimated price
$320 - $1,600
Flights from Fort Wayne to Asheville via Chicago O'Hare
Ave. Duration
7 h 7 min
When
Every day
Estimated price
$340 - $1,600
Allegiant Air
Website
allegiantair.com
Flights from Fort Wayne to Asheville via Orlando Sanford
Ave. Duration
4 h 47 min
When
Sunday
Estimated price
$310 - $1,400
Flights from Fort Wayne to Asheville via Punta Gorda
Ave. Duration
6 h 13 min
When
Tuesday
Estimated price
$340 - $1,600
Bus operators
Barons Bus
Phone
+1 888-378-3823
Website
baronsbus.com
Bus from Fort Wayne, IN to Columbus, OH
Ave. Duration
3 h 30 min
Frequency
Once daily
Estimated price
$22 - $40
Book at
baronsbus.com
Bus from Fort Wayne, IN to Columbus, OH
Ave. Duration
4 h 20 min
Frequency
Once daily
Estimated price
$22 - $50
Book at
baronsbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to Winston Salem, Nc
Ave. Duration
10 h 35 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50

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