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How to get fromFort Pierce to St. LouisBy car, plane, bus (Flixbus, Greyhound), shuttle, bus, or bus (Greyhound)

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There are 6 ways to get from Fort Pierce to St. Louis by car, plane, bus (Flixbus, Greyhound), shuttle, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Midamerica St. Louis Airport

    best
    1. Drive from Fort Pierce to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Midamerica St. Louis Airport (BLV)plane plane SFB - BLV
    5h 54m
    $128–484

  2. Bus

    1. Take the bus from Port St Lucie to Atlanta Bus Stationbus bus FlixBus N2401
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    24h 34m
    $142–304

  3. Drive 1,096.9 mi

    1. Drive from Fort Pierce to St. Louiscar car 1,096.9 mi
    18h 5m
    $201–290

  4. Shuttle to Orlando, fly to Lambert–St. Louis International Airport

    1. Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    7h 38m
    $316–936

  5. Bus to Fort Lauderdale–Hollywood International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Lambert–St. Louis International Airport (STL)plane plane FLL - STL
    7h 41m
    $240–651

  6. Bus via Clarksville Park & Ride

    1. Take the bus from Fort Pierce to Orlando - RedCoach Station, FLbus bus
    2. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus bus
    3. Take the bus from Atlanta Bus Station to Clarksville Park & Ridebus bus
    4. Take the bus from Clarksville Park & Ride to St Louis Bus Stationbus bus
    24h 47m
    $231–437

Fort Pierce to St. Louis by bus

Calendar7Weekly Buses
Duration24h 34mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

What companies run services between Fort Pierce, FL, USA and St. Louis, MO, USA?

You can take a bus from Orange Ave & N 9th St to St Louis Bus Station via Wheeler Ter & Okeechobee Rd, Fort Pierce, Port St Lucie, and Atlanta Bus Station in around 24h 34m.

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