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How to get fromFort Pierce to Des Moinesby car, plane, bus (Greyhound, Flixbus), bus, train or taxi

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There are 8 ways to get from Fort Pierce to Des Moines by car, plane, bus (Greyhound, Flixbus), bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly

    best
    1. Drive from Fort Pierce to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    5h 39m
    $129–503
  2. Bus to Fort Lauderdale–Hollywood International Airport, fly

    cheapest
    1. Take the bus from Fort Pierce to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Des Moines (DSM)plane plane FLL - DSM
    7h 50m
    $115–514
  3. Bus

    1. Take the bus from Fort Pierce to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    47h 22m
    $237–519
  4. Bus, train

    1. Take the bus from Fort Pierce to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    2d 8h
    $306–762
  5. Drive 1,427.1 mi

    1. Drive from Fort Pierce to Des Moinescar car 1,427.1 mi
    24h 38m
    $261–377
  6. Bus, taxi to Melbourne International Airport, fly

    1. Take the bus from Fort Pierce to Sebastianbus bus
    2. Take the taxi from Sebastian to Melbourne International Airport (MLB)taxi taxi
    3. Fly from Melbourne International Airport (MLB) to Des Moines (DSM)plane plane MLB - DSM
    9h 31m
    $204–615
  7. Bus to Miami International Airport, fly

    1. Take the bus from Fort Pierce to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Des Moines (DSM)plane plane MIA - DSM
    8h 44m
    $130–584
  8. Bus to Palm Beach International Airport, fly

    1. Take the bus from Fort Pierce to West Palm Beach, FLbus bus
    2. Fly from Palm Beach International Airport (PBI) to Des Moines (DSM)plane plane PBI - DSM
    9h 56m
    $155–755

Fort Pierce to Des Moines by bus

Calendar5Weekly Buses
Duration47h 22mAverage Duration
Ticket$237Cheapest Price
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Questions & Answers

What companies run services between Fort Pierce, FL, USA and Des Moines, IA, USA?

You can take a bus from Orange Ave & N 9th St to Des Moines via Wheeler Ter & Okeechobee Rd, Fort Pierce, Jacksonville, Washington Union Station, and Chicago Bus Station in around 47h 22m.

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