There are 9 ways to get from Fort Pierce to Big Pine Key by bus (Greyhound), car, bus, plane, shuttle, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Miami Airport (MIA)
best- Take the bus from Fort Pierce to Miami Airportbus Tallahassee-Miami
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
8h 23m$44–163Bus, train
cheapest- Take the bus from Fort Pierce to West Palm Beach, FLbus
- Take the train from West Palm Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
9h 14m$42–173Drive 256.2 mi
- Drive from Fort Pierce to Big Pine Keycar 256.2 mi
4h 54m$47–68Bus to Miami International Airport, fly to Key West International Airport, bus
- Take the bus from Fort Pierce to Miami Airportbus
- Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane MIA - EYW
- Take the bus from Key West Airport to Big Pine Keybus
7h 29m$193–747Bus, shuttle
- Take the bus from Fort Pierce to Fort Lauderdale Airportbus Tallahassee-Miami
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLTo the Keys
7h 33m$193–333Bus (Greyhound)
- Take the bus from Fort Pierce to Miami Airport Stationbus Greyhound US0630 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
9h 18m$54–93Shuttle to Orlando, fly to Key West International Airport, bus
- Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airport
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
- Take the bus from Key West Airport to Big Pine Keybus
7h 16m$143–397Bus to Fort Lauderdale–Hollywood International Airport, fly to Key West International Airport, bus
- Take the bus from Fort Pierce to Fort Lauderdale Airportbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Key West International Airport (EYW)plane FLL - EYW
- Take the bus from Key West Airport to Big Pine Keybus
6h 33m$103–567Shuttle to Orlando, fly to Miami International Airport, shuttle
- Take a shuttle bus from Fort Pierce, FL - Dunkin' Donuts to Orlando Airport
- Fly from Orlando (MCO) to Miami International Airport (MIA)plane MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 30m$303–613
Fort Pierce to Big Pine Key by bus and tram
Questions & Answers
The cheapest way to get from Fort Pierce to Big Pine Key is to bus and train which costs $40 - $180 and takes 9h 14m.
The fastest way to get from Fort Pierce to Big Pine Key is to drive which takes 4h 54m and costs $45 - $70.
No, there is no direct bus from Fort Pierce to Big Pine Key. However, there are services departing from Orange Ave & N 9th St and arriving at Big Pine Key via Fort Pierce and Miami Airport Station. The journey, including transfers, takes approximately 9h 18m.
The distance between Fort Pierce and Big Pine Key is 262 miles. The road distance is 257.7 miles.
The best way to get from Fort Pierce to Big Pine Key without a car is to bus via Miami Airport (MIA) which takes 8h 23m and costs $40 - $170.
It takes approximately 8h 23m to get from Fort Pierce to Big Pine Key, including transfers.
Fort Pierce to Big Pine Key bus services, operated by Greyhound USA, depart from Fort Pierce station.
Fort Pierce to Big Pine Key bus services, operated by Greyhound USA, arrive at Miami Airport Station.
Yes, the driving distance between Fort Pierce to Big Pine Key is 258 miles. It takes approximately 4h 54m to drive from Fort Pierce to Big Pine Key.
There are 76+ hotels available in Big Pine Key.
What companies run services between Fort Pierce, FL, USA and Big Pine Key, FL, USA?
You can take a bus from Orange Ave & N 9th St to Big Pine Key via Wheeler Ter & Okeechobee Rd, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 8h 23m.
- Website
- aa.com
Flights from Miami International Airport to Key West International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $40–320
Flights from Orlando to Key West International Airport via Miami International Airport
- Ave. Duration
- 3h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $50–340
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $30–230
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $30–230
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 16m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–170
- Website
- spirit.com
Flights from Fort Lauderdale–Hollywood International Airport to Key West International Airport
- Ave. Duration
- 50 min
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $60–220
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Pierce to Miami Airport
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $23–140
- Website
- https://www.redcoachusa.com
- Web
- $23–140
Bus from Fort Pierce to Fort Lauderdale Airport
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
Bus from Fort Pierce to West Palm Beach, FL
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- $21–140
- Website
- https://www.redcoachusa.com
- Web
- $21–140
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–30
- Website
- https://www.greyhound.com/
Bus from Key West Airport to Big Pine Key
- Ave. Duration
- 40 min
- Frequency
- 3 times a day
- Estimated price
- $10–14
- Website
- https://www.greyhound.com/
Bus from Fort Pierce to West Palm Beach, FL
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $16–22
- Website
- https://www.greyhound.com/
Bus from Fort Pierce to Miami Airport Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Fort Pierce, FL - Dunkin' Donuts to Orlando Airport
- Ave. Duration
- 1h 57m
- Frequency
- 4 times a day
- Estimated price
- $70–85
- Schedules at
- smartshuttleline.com
- one passenger
- $70–85
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide











