There are 8 ways to get from Fort Myers to Winston-Salem by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Ft. Myers to Raleigh/Durham, bus  •  8 h 40 min

  1. Fly from Ft. Myers (RSW) to Raleigh/Durham (RDU) RSW - RDU
  2. Take the bus from Durham, Nc to Winston Salem, Nc

$102 - $426

7 alternative options

Fly Ft. Myers to Greensboro/High Point  •  9 h 18 min

  1. Fly from Ft. Myers (RSW) to Greensboro/High Point (GSO) RSW - GSO

$190 - $961

Bus to Miami, fly to Greensboro/High Point  •  8 h 32 min

  1. Take the bus from Fort Myers, FL to Miami Airport
  2. Fly from Miami (MIA) to Greensboro/High Point (GSO) MIA - GSO

$197 - $455

Line 140 bus to Ft. Myers, fly to Charlotte, train, line 5 bus  •  9 h 30 min

  1. Take the line 140 bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
  2. Fly from Ft. Myers (RSW) to Charlotte (CLT) RSW - CLT
  3. Take the train from Charlotte Amtrak to High Point Amtrak
  4. Take the line 5 bus from High Point Amtrak Station to Winston-Salem Transportation Center

$176 - $381

Bus to Punta Gorda, fly to Concord, train, line 5 bus  •  7 h 6 min

  1. Take the bus from Fort Myers - Walmart to Punta Gorda, FL - Pilot
  2. Fly from Punta Gorda (PGD) to Concord (USA) PGD - USA
  3. Take the train from Kannapolis Amtrak to High Point Amtrak
  4. Take the line 5 bus from High Point Amtrak Station to Winston-Salem Transportation Center

$189 - $423

Bus, bus to Sarasota/Bradenton, fly to Charlotte, train  •  10 h 45 min

  1. Take the bus from Ft Myers, Fl to Port Charlotte, Fl
  2. Take the bus from Port Charlotte, Fl to Sarasota, Fl
  3. Fly from Sarasota/Bradenton (SRQ) to Charlotte (CLT) SRQ - CLT
  4. Take the train from Charlotte Amtrak to High Point Amtrak

$194 - $524

Bus, train  •  22 h 38 min

  1. Take the bus from Ft Myers, Fl to Port Charlotte, Fl
  2. Take the bus from Port Charlotte, Fl to Tampa, Fl
  3. Take the train from Tampa Amtrak to Cary Amtrak
  4. Take the train from Cary Amtrak to Greensboro Galyon Transportation Center
  5. Take the bus from Greensboro, Nc to Winston Salem, Nc

$161 - $426

Drive  •  13 h 7 min

  1. Drive from Fort Myers to Winston-Salem 758.4 miles

$70 - $110

Questions & Answers

The distance between Fort Myers and Winston-Salem is 665 miles. The road distance is 758.4 miles.

Get driving directions

The best way to get from Fort Myers to Winston-Salem without a car is to bus and train which takes 22 h 38 min and costs .

More details

It takes approximately 8 h 40 min to get from Fort Myers to Winston-Salem, including transfers.

More details

The quickest flight from Ft. Myers Airport to Raleigh/Durham Airport is the direct flight which takes 1 h 50 min.

Search flights

Yes, the driving distance between Fort Myers to Winston-Salem is 758 miles. It takes approximately 13 h 7 min to drive from Fort Myers to Winston-Salem.

Get driving directions

Frontier Airlines, Southwest Airlines, American Airlines and Delta offer flights from Ft. Myers Airport to Raleigh/Durham Airport.

Search flights

There are 48+ hotels available in Winston-Salem. Prices start at $59 USD per night.

More details

Map of how to get from Fort Myers to Winston-Salem.
Launch map view
  • Distance: 665.4 miles
  • Duration: 8 h 40 min

What companies run services between Fort Myers, FL, USA and Winston-Salem, NC, USA?

American Airlines, Delta and two other airlines fly from Fort Myers to Winston-Salem hourly.

Airlines
Delta
Website
delta.com
Flights from Ft. Myers to Raleigh/Durham via Atlanta
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$140 - $700
Flights from Ft. Myers to Greensboro/High Point via Atlanta
Ave. Duration
4 h 56 min
When
Every day
Estimated price
$180 - $950
Flights from Ft. Myers to Greensboro/High Point via Detroit
Ave. Duration
5 h 58 min
When
Saturday
Estimated price
$240 - $1,100
Flights from Ft. Myers to Greensboro/High Point via New York La Guardia
Ave. Duration
7 h 5 min
When
Every day
Estimated price
$240 - $1,100
Flights from Miami to Greensboro/High Point via Atlanta
Ave. Duration
4 h 35 min
When
Every day
Estimated price
$160 - $650
Flights from Ft. Myers to Charlotte via Atlanta
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$170 - $650
Flights from Sarasota/Bradenton to Charlotte via Atlanta
Ave. Duration
3 h 58 min
When
Saturday
Estimated price
$310 - $700
American Airlines
Website
aa.com
Flights from Ft. Myers to Raleigh/Durham via Charlotte
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$140 - $700
Flights from Ft. Myers to Greensboro/High Point via Charlotte
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$190 - $900
Flights from Ft. Myers to Greensboro/High Point via Reagan Washington
Ave. Duration
5 h 34 min
When
Wednesday, Thursday and Friday
Estimated price
$220 - $1,000
Flights from Ft. Myers to Greensboro/High Point via Miami
Ave. Duration
6 h 11 min
When
Every day
Estimated price
$200 - $950
Flights from Ft. Myers to Greensboro/High Point via Dallas/Ft.Worth
Ave. Duration
6 h 47 min
When
Saturday
Estimated price
$290 - $1,100
Flights from Ft. Myers to Greensboro/High Point via Chicago O'Hare
Ave. Duration
7 h 25 min
When
Every day
Estimated price
$270 - $1,100
Flights from Ft. Myers to Greensboro/High Point via Philadelphia
Ave. Duration
7 h 56 min
When
Every day
Estimated price
$240 - $1,000
Flights from Miami to Greensboro/High Point
Ave. Duration
2 h 8 min
When
Every day
Estimated price
$150 - $650
Flights from Miami to Greensboro/High Point via Charlotte
Ave. Duration
4 h 26 min
When
Every day
Estimated price
$150 - $650
Flights from Ft. Myers to Charlotte
Ave. Duration
1 h 57 min
When
Every day
Estimated price
$290 - $700
Flights from Ft. Myers to Charlotte via Miami
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$290 - $700
Flights from Sarasota/Bradenton to Charlotte
Ave. Duration
1 h 52 min
When
Every day
Estimated price
$290 - $700
Southwest Airlines
Website
southwest.com
Flights from Ft. Myers to Raleigh/Durham via Atlanta
Ave. Duration
4 h 2 min
When
Monday to Saturday
Estimated price
$160 - $700
Flights from Ft. Myers to Raleigh/Durham via Baltimore
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$190 - $750
United Airlines
Website
united.com
Flights from Ft. Myers to Greensboro/High Point via Newark
Ave. Duration
6 h 16 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,100
Flights from Ft. Myers to Greensboro/High Point via Chicago O'Hare
Ave. Duration
7 h 3 min
When
Saturday and Sunday
Estimated price
$270 - $1,200
Frontier Airlines
Website
flyfrontier.com
Flights from Ft. Myers to Raleigh/Durham
Ave. Duration
1 h 50 min
When
Wednesday and Saturday
Estimated price
$80 - $380
Allegiant Air
Website
allegiantair.com
Flights from Punta Gorda to Concord
Ave. Duration
1 h 47 min
When
Monday and Friday
Estimated price
$70 - $260
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Charlotte Amtrak to High Point Amtrak
Ave. Duration
1 h 13 min
Frequency
5 times a day
Estimated price
$27 - $60
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$40 - $60
Room
$150 - $210
Train from Kannapolis Amtrak to High Point Amtrak
Ave. Duration
48 min
Frequency
4 times a day
Estimated price
$24 - $50
Website
amtrak.com
Coach Seat
$24 - $35
Flexi Coach Seat
$40 - $65
Business Coach Seat
$30 - $50
Room
$140 - $200
Train from Tampa Amtrak to Cary Amtrak
Ave. Duration
14 h 41 min
Frequency
Once daily
Estimated price
$100 - $290
Website
amtrak.com
Coach Seat
$100 - $150
Flexi Coach Seat
$180 - $260
Business Coach Seat
$200 - $290
Room
$410 - $600
Train from Cary Amtrak to Greensboro Galyon Transportation Center
Ave. Duration
1 h 19 min
Frequency
4 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Durham, Nc to Winston Salem, Nc
Ave. Duration
2 h
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Ft Myers, Fl to Port Charlotte, Fl
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$10 - $21
Website
greyhound.com
Economy
$10 - $14
Flexible
$17 - $21
Bus from Port Charlotte, Fl to Sarasota, Fl
Ave. Duration
50 min
Frequency
Hourly
Estimated price
$10 - $23
Website
greyhound.com
Economy
$10 - $15
Flexible
$18 - $23
Bus from Port Charlotte, Fl to Tampa, Fl
Ave. Duration
2 h 20 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from Fort Myers, FL to Miami Airport
Ave. Duration
2 h 25 min
Frequency
Every 3 hours
Estimated price
$40 - $50
Schedules at
javaxbus.com
Book at
gotobus.com
Bus from Fort Myers - Walmart to Punta Gorda, FL - Pilot
Ave. Duration
30 min
Frequency
3 times a day
Estimated price
$49
Schedules at
javaxbus.com
Book at
gotobus.com
Lee County Transit
Phone
+1 239-533-2111
Website
rideleetran.com
Bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
Ave. Duration
25 min
Frequency
Every 30 minutes
Estimated price
$1 - $3
Schedules at
leegov.com
PART NC
Phone
+1 336-662-0002
Website
partnc.org
Bus from High Point Amtrak Station to Winston-Salem Transportation Center
Ave. Duration
38 min
Frequency
Every 4 hours
Estimated price
$3
Schedules at
partnc.org
Sunway Charters
Phone
+1 704-348-1200
Email
info@sunwaycharters.com
Website
sunwaycharters.com
Bus from Greensboro, Nc to Winston-Salem
Ave. Duration
40 min
Frequency
Twice daily
Schedules at
sunwaycharters.com

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