• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 10 ways to get from Fort Myers to Winston-Salem by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Ft. Myers to Greensboro/High Point  •  9h 19m

  1. Fly from Ft. Myers (RSW) to Greensboro/High Point (GSO) RSW - GSO

$190 - $961

Cheapest option

Fly Ft. Myers to Raleigh/Durham, bus  •  9h 19m

  1. Fly from Ft. Myers (RSW) to Raleigh/Durham (RDU) RSW - RDU
  2. Take the bus from Durham, Nc to Winston Salem, Nc

$102 - $426

8 alternative options

Line 140 bus to Ft. Myers, fly to Charlotte, train, line 5 bus  •  9h 27m

  1. Take the line 140 bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
  2. Fly from Ft. Myers (RSW) to Charlotte (CLT) RSW - CLT
  3. Take the train from Charlotte Amtrak Station to High Point Amtrak Station
  4. Take the line 5 bus from High Point Amtrak Station to Winston-Salem Transportation Center

$178 - $384

Fly Punta Gorda to Concord, train  •  6h 4m

  1. Fly from Punta Gorda (PGD) to Concord (USA) PGD - USA
  2. Take the train from Kannapolis Amtrak Station to High Point Amtrak Station

$216 - $463

Bus to Sarasota/Bradenton, fly to Charlotte, train  •  11h 10m

  1. Take the bus from Ft Myers, Fl to Sarasota, Fl
  2. Fly from Sarasota/Bradenton (SRQ) to Charlotte (CLT) SRQ - CLT
  3. Take the train from Charlotte Amtrak Station to High Point Amtrak Station

$190 - $513

Bus to Tampa, fly to Charlotte, train  •  11h 53m

  1. Take the bus from Ft Myers, Fl to Tampa, Fl
  2. Fly from Tampa (TPA) to Charlotte (CLT) TPA - CLT
  3. Take the train from Charlotte Amtrak Station to High Point Amtrak Station

$195 - $466

Bus to Miami, fly to Greensboro/High Point  •  11h 29m

  1. Take the bus from Fort Myers, FL - McDonalds to Miami Airport
  2. Fly from Miami (MIA) to Greensboro/High Point (GSO) MIA - GSO

$186 - $472

Bus La Cubana, train  •  17h 40m

  1. Take the bus from Fort Myers, FL to Charlotte, NC Atlanta route
  2. Take the train from Charlotte Amtrak Station to High Point Amtrak Station Piedmont / ...

$154 - $259

Bus, train via Tampa, Fl  •  23h 26m

  1. Take the bus from Ft Myers, Fl to Tampa, Fl
  2. Take the train from Tampa Union Station to Cary Amtrak Station
  3. Take the train from Cary Amtrak Station to Greensboro Amtrak Station
  4. Take the bus from Greensboro, Nc to Winston Salem, Nc

$154 - $409

Drive  •  13h 7m

  1. Drive from Fort Myers to Winston-Salem 758.4 miles

$70 - $110

Questions & Answers

The cheapest way to get from Fort Myers to Winston-Salem is to drive which costs $70 - $110 and takes 13h 7m.

More details

The quickest way to get from Fort Myers to Winston-Salem is to fly and train which costs $210 - $470 and takes 6h 4m.

More details

The distance between Fort Myers and Winston-Salem is 665 miles. The road distance is 758.4 miles.

Get driving directions

The best way to get from Fort Myers to Winston-Salem without a car is to bus and train which takes 17h 40m and costs $150 - $260.

More details

It takes approximately 9h 19m to get from Fort Myers to Winston-Salem, including transfers.

More details

There is no direct flight from Ft. Myers Airport to Greensboro/High Point Airport. The quickest flight takes 3h 34m and has one stopover.

Search flights

Yes, the driving distance between Fort Myers to Winston-Salem is 758 miles. It takes approximately 13h 7m to drive from Fort Myers to Winston-Salem.

Get driving directions

United Airlines, Delta and American Airlines offer flights from Ft. Myers Airport to Greensboro/High Point Airport.

Search flights

There are 47+ hotels available in Winston-Salem. Prices start at $55 USD per night.

More details

The best way to get from Fort Myers to Punta Gorda Airport is to taxi which takes 33m and costs $80 - $100.

More details

Map of how to get from Fort Myers to Winston-Salem.
Launch map view
  • Distance: 665.4 miles
  • Duration: 9h 19m

What companies run services between Fort Myers, FL, USA and Winston-Salem, NC, USA?

American Airlines, Delta and United Airlines fly from Fort Myers to Winston-Salem hourly.

Airlines
American Airlines
Website
aa.com
Flights from Ft. Myers to Greensboro/High Point via Charlotte
Ave. Duration
4h 30m
When
Every day
Estimated price
$190 - $900
Flights from Ft. Myers to Greensboro/High Point via Reagan Washington
Ave. Duration
5h 30m
When
Monday to Friday
Estimated price
$220 - $1,000
Flights from Ft. Myers to Greensboro/High Point via Chicago O'Hare
Ave. Duration
6h 44m
When
Every day
Estimated price
$270 - $1,100
Flights from Ft. Myers to Greensboro/High Point via Philadelphia
Ave. Duration
5h 58m
When
Monday, Thursday, Friday and Sunday
Estimated price
$240 - $1,000
Flights from Ft. Myers to Greensboro/High Point via Miami
Ave. Duration
6h 15m
When
Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$200 - $950
Flights from Ft. Myers to Greensboro/High Point via Dallas/Ft.Worth
Ave. Duration
6h 59m
When
Every day
Estimated price
$290 - $1,100
Flights from Ft. Myers to Raleigh/Durham via Charlotte
Ave. Duration
3h 48m
When
Every day
Estimated price
$140 - $700
Flights from Ft. Myers to Raleigh/Durham via Miami
Ave. Duration
4h 17m
When
Monday, Thursday, Friday and Sunday
Estimated price
$150 - $700
Flights from Ft. Myers to Charlotte
Ave. Duration
1h 56m
When
Every day
Estimated price
$290 - $700
Flights from Ft. Myers to Charlotte via Miami
Ave. Duration
4h 6m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$290 - $700
Flights from Sarasota/Bradenton to Charlotte
Ave. Duration
1h 47m
When
Every day
Estimated price
$290 - $700
Flights from Tampa to Charlotte
Ave. Duration
1h 46m
When
Every day
Estimated price
$300 - $750
Flights from Miami to Greensboro/High Point
Ave. Duration
2h 9m
When
Every day
Estimated price
$150 - $650
Flights from Miami to Greensboro/High Point via Charlotte
Ave. Duration
4h 26m
When
Every day
Estimated price
$150 - $650
Delta
Website
delta.com
Flights from Ft. Myers to Greensboro/High Point via Atlanta
Ave. Duration
4h 31m
When
Every day
Estimated price
$180 - $950
Flights from Ft. Myers to Greensboro/High Point via New York La Guardia
Ave. Duration
5h 50m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,100
Flights from Ft. Myers to Greensboro/High Point via Detroit
Ave. Duration
6h 2m
When
Every day
Estimated price
$240 - $1,100
Flights from Ft. Myers to Raleigh/Durham via Atlanta
Ave. Duration
4h 14m
When
Every day
Estimated price
$140 - $700
Flights from Ft. Myers to Charlotte via Atlanta
Ave. Duration
4h 8m
When
Every day
Estimated price
$170 - $650
Flights from Sarasota/Bradenton to Charlotte via Atlanta
Ave. Duration
4h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $700
Flights from Miami to Greensboro/High Point via Atlanta
Ave. Duration
4h 33m
When
Every day
Estimated price
$160 - $650
United Airlines
Website
united.com
Flights from Ft. Myers to Greensboro/High Point via Chicago O'Hare
Ave. Duration
6h 19m
When
Every day
Estimated price
$270 - $1,200
Flights from Ft. Myers to Greensboro/High Point via Newark
Ave. Duration
6h 28m
When
Monday to Saturday
Estimated price
$260 - $1,100
Frontier Airlines
Website
flyfrontier.com
Flights from Ft. Myers to Raleigh/Durham
Ave. Duration
1h 51m
When
Wednesday and Saturday
Estimated price
$80 - $380
Flights from Tampa to Charlotte
Ave. Duration
1h 50m
When
Tuesday, Thursday and Sunday
Estimated price
$70 - $350
Southwest Airlines
Website
southwest.com
Flights from Ft. Myers to Raleigh/Durham via Atlanta
Ave. Duration
4h
When
Monday to Saturday
Estimated price
$160 - $700
Allegiant Air
Website
allegiantair.com
Flights from Punta Gorda to Concord
Ave. Duration
1h 47m
When
Monday and Friday
Estimated price
$70 - $260
Corporate Flight Management
Website
contouraviation.com
Flights from Tampa to Charlotte
Ave. Duration
1h 40m
When
Saturday
Estimated price
$60 - $410
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Charlotte Amtrak Station to High Point Amtrak Station
Ave. Duration
1h 13m
Frequency
5 times a day
Estimated price
$27 - $60
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$40 - $60
Room
$150 - $210
Train from Kannapolis Amtrak Station to High Point Amtrak Station
Ave. Duration
48m
Frequency
4 times a day
Estimated price
$24 - $50
Website
amtrak.com
Coach Seat
$24 - $35
Flexi Coach Seat
$40 - $65
Business Coach Seat
$30 - $50
Room
$140 - $200
Train from Tampa Union Station to Cary Amtrak Station
Ave. Duration
14h 41m
Frequency
Once daily
Estimated price
$100 - $290
Website
amtrak.com
Coach Seat
$100 - $150
Flexi Coach Seat
$180 - $260
Business Coach Seat
$200 - $290
Room
$410 - $600
Train from Cary Amtrak Station to Greensboro Amtrak Station
Ave. Duration
1h 19m
Frequency
4 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Durham, Nc to Winston Salem, Nc
Ave. Duration
2h
Frequency
4 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Ft Myers, Fl to Sarasota, Fl
Ave. Duration
2h 5m
Frequency
4 times a day
Estimated price
$13 - $30
Website
greyhound.com
Economy
$13 - $20
Flexible
$23 - $30
Bus from Ft Myers, Fl to Tampa, Fl
Ave. Duration
3h 35m
Frequency
4 times a day
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45m
Frequency
4 times a day
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Lee County Transit
Phone
+1 239-533-2111
Website
rideleetran.com
Bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
Ave. Duration
25m
Frequency
Every 30 minutes
Estimated price
$1 - $3
Schedules at
leegov.com
PART NC
Phone
+1 336-662-0002
Website
partnc.org
Bus from High Point Amtrak Station to Winston-Salem Transportation Center
Ave. Duration
38m
Frequency
Every 4 hours
Estimated price
$3
Schedules at
partnc.org
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Fort Myers, FL - McDonalds to Miami Airport
Ave. Duration
2h 50m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Fort Myers, FL to Charlotte, NC
Ave. Duration
13h 35m
Frequency
Once daily
Estimated price
$95 - $160
Schedules at
lacubanabus.com
Sunway Charters
Phone
+1 704-348-1200
Email
info@sunwaycharters.com
Website
sunwaycharters.com
Bus from Greensboro, Nc to Winston-Salem
Ave. Duration
40m
Frequency
Twice daily
Schedules at
sunwaycharters.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.