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There are 9 ways to get from Fort Myers to San Antonio by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Ft. Myers to San Antonio  •  8h 38m

  1. Fly from Ft. Myers (RSW) to San Antonio (SAT) RSW - SAT

$226 - $957

Cheapest option

Bus  •  35h 34m

  1. Take the bus from Ft Myers, Fl to Orlando, Fl
  2. Take the bus from Orlando, Fl to Houston, Tx
  3. Take the bus from Houston, Tx to San Antonio, Tx

$146 - $362

7 alternative options

Bus to Tampa, fly to San Antonio  •  9h 18m

  1. Take the bus from Ft Myers, Fl to Tampa, Fl
  2. Fly from Tampa (TPA) to San Antonio (SAT) TPA - SAT

$193 - $599

Bus, bus to Orlando, fly to San Antonio  •  11h 21m

  1. Take the bus from Ft Myers, Fl to Port Charlotte, Fl
  2. Take the bus from Port Charlotte,FL - Burger King to Orlando, FL - McDonalds
  3. Fly from Orlando (MCO) to San Antonio (SAT) MCO - SAT

$192 - $636

Bus to Tampa, fly to Austin, bus  •  11h 28m

  1. Take the bus from Ft Myers, Fl to Tampa, Fl
  2. Fly from Tampa (TPA) to Austin (AUS) TPA - AUS
  3. Take the bus from Austin, Tx to San Antonio, Tx

$187 - $530

Bus to Fort Lauderdale, fly to San Antonio  •  9h 47m

  1. Take the bus from Fort Myers, FL - McDonalds to Fort Lauderdale – Hollywood International Airport
  2. Fly from Fort Lauderdale (FLL) to San Antonio (SAT) FLL - SAT

$152 - $668

Bus to Miami, fly to San Antonio  •  10h 38m

  1. Take the bus from Fort Myers, FL - McDonalds to Miami Airport
  2. Fly from Miami (MIA) to San Antonio (SAT) MIA - SAT

$212 - $618

Bus, train  •  38h 21m

  1. Take the bus from Ft Myers, Fl to Orlando, Fl
  2. Take the bus from Orlando, Fl to Lafayette, La
  3. Take the train from Lafayette Amtrak Station to San Antonio Amtrak Station

$167 - $432

Drive  •  21h 1m

  1. Drive from Fort Myers to San Antonio 1306.1 miles

$120 - $190

Questions & Answers

The cheapest way to get from Fort Myers to San Antonio is to drive which costs $120 - $190 and takes 21h 1m.

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The quickest way to get from Fort Myers to San Antonio is to fly which costs $220 - $1,000 and takes 8h 38m.

More details

No, there is no direct bus from Fort Myers to San Antonio. However, there are services departing from Ft Myers, Fl and arriving at San Antonio, Tx via Orlando, Fl and Houston, Tx. The journey, including transfers, takes approximately 35h 34m.

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The distance between Fort Myers and San Antonio is 1039 miles. The road distance is 1306.1 miles.

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The best way to get from Fort Myers to San Antonio without a car is to bus which takes 35h 34m and costs $140 - $370.

More details

It takes approximately 8h 38m to get from Fort Myers to San Antonio, including transfers.

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Fort Myers to San Antonio bus services, operated by Greyhound USA, depart from Ft Myers, Fl station.

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The best way to get from Fort Myers to San Antonio is to fly which takes 8h 38m and costs $220 - $1,000. Alternatively, you can bus, which costs $140 - $370 and takes 35h 34m.

Mode details

There is no direct flight from Ft. Myers Airport to San Antonio Airport. The quickest flight takes 4h 51m and has one stopover.

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Fort Myers to San Antonio bus services, operated by Greyhound USA, arrive at San Antonio, Tx station.

More details

Map of how to get from Fort Myers to San Antonio.
Launch map view
  • Distance: 1039.1 miles
  • Duration: 8h 38m

What companies run services between Fort Myers, FL, USA and San Antonio, TX, USA?

United Airlines, Southwest Airlines and two other airlines fly from Fort Myers to San Antonio hourly. Alternatively, you can take a bus from Fort Myers to San Antonio via Orlando, Fl and Houston, Tx in around 35h 34m.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Ft. Myers to San Antonio via Dallas
Ave. Duration
5h 38m
When
Every day
Estimated price
$240 - $950
Flights from Ft. Myers to San Antonio via Atlanta
Ave. Duration
5h 25m
When
Monday to Friday
Estimated price
$260 - $1,000
Flights from Ft. Myers to San Antonio via St. Louis
Ave. Duration
6h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,100
Flights from Ft. Myers to San Antonio via Baltimore
Ave. Duration
7h 10m
When
Saturday
Estimated price
$340 - $1,200
Flights from Tampa to San Antonio
Ave. Duration
2h 51m
When
Every day
Estimated price
$390 - $1,200
Flights from Tampa to San Antonio via Houston Hobby Apt
Ave. Duration
4h 30m
When
Every day
Estimated price
$390 - $1,200
Flights from Tampa to San Antonio via Dallas
Ave. Duration
4h 58m
When
Monday to Saturday
Estimated price
$390 - $1,200
Flights from Orlando to San Antonio
Ave. Duration
3h
When
Every day
Estimated price
$310 - $1,300
Flights from Orlando to San Antonio via Houston Hobby Apt
Ave. Duration
4h 47m
When
Every day
Estimated price
$310 - $1,300
Flights from Orlando to San Antonio via Dallas
Ave. Duration
5h
When
Monday to Friday
Estimated price
$310 - $1,300
Flights from Tampa to Austin
Ave. Duration
2h 45m
When
Every day
Estimated price
$440 - $1,400
Flights from Tampa to Austin via Houston Hobby Apt
Ave. Duration
4h 18m
When
Every day
Estimated price
$440 - $1,400
Flights from Tampa to Austin via New Orleans
Ave. Duration
4h 50m
When
Monday to Friday
Estimated price
$440 - $1,400
Flights from Tampa to Austin via Dallas
Ave. Duration
4h 50m
When
Saturday
Estimated price
$440 - $1,400
Flights from Fort Lauderdale to San Antonio
Ave. Duration
3h 18m
When
Every day
Estimated price
$250 - $1,400
Flights from Fort Lauderdale to San Antonio via Houston Hobby Apt
Ave. Duration
5h 2m
When
Every day
Estimated price
$250 - $1,400
Flights from Fort Lauderdale to San Antonio via New Orleans
Ave. Duration
4h 50m
When
Sunday
Estimated price
$250 - $1,400
Flights from Fort Lauderdale to San Antonio via Orlando
Ave. Duration
5h 10m
When
Sunday
Estimated price
$250 - $1,400
Flights from Fort Lauderdale to San Antonio via Dallas
Ave. Duration
5h 15m
When
Saturday
Estimated price
$250 - $1,400
American Airlines
Website
aa.com
Flights from Ft. Myers to San Antonio via Dallas/Ft.Worth
Ave. Duration
5h 25m
When
Every day
Estimated price
$220 - $950
Flights from Ft. Myers to San Antonio via Charlotte
Ave. Duration
6h 10m
When
Wednesday, Saturday and Sunday
Estimated price
$250 - $1,000
Flights from Ft. Myers to San Antonio via Chicago O'Hare
Ave. Duration
7h 7m
When
Every day
Estimated price
$290 - $1,100
Flights from Tampa to San Antonio via Dallas/Ft.Worth
Ave. Duration
5h 5m
When
Every day
Estimated price
$200 - $1,100
Flights from Tampa to Austin via Dallas/Ft.Worth
Ave. Duration
4h 45m
When
Every day
Estimated price
$290 - $1,000
Flights from Miami to San Antonio
Ave. Duration
3h 16m
When
Every day
Estimated price
$280 - $1,100
Flights from Miami to San Antonio via Dallas/Ft.Worth
Ave. Duration
5h 37m
When
Every day
Estimated price
$280 - $1,100
United Airlines
Website
united.com
Flights from Ft. Myers to San Antonio via Houston
Ave. Duration
5h 4m
When
Every day
Estimated price
$210 - $950
Flights from Tampa to San Antonio via Houston
Ave. Duration
4h 54m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,100
Flights from Orlando to San Antonio via Houston
Ave. Duration
4h 40m
When
Every day
Estimated price
$330 - $1,100
Flights from Tampa to Austin via Houston
Ave. Duration
4h 40m
When
Every day
Estimated price
$330 - $1,100
Flights from Fort Lauderdale to San Antonio via Houston
Ave. Duration
5h
When
Every day
Estimated price
$230 - $1,200
Flights from Miami to San Antonio via Houston
Ave. Duration
5h 16m
When
Every day
Estimated price
$300 - $1,100
Delta
Website
delta.com
Flights from Ft. Myers to San Antonio via Atlanta
Ave. Duration
6h 16m
When
Every day
Estimated price
$210 - $950
Flights from Tampa to Austin via Atlanta
Ave. Duration
4h 48m
When
Monday to Friday
Estimated price
$290 - $1,200
Flights from Miami to San Antonio via Atlanta
Ave. Duration
5h 47m
When
Every day
Estimated price
$200 - $1,200
Frontier Airlines
Website
flyfrontier.com
Flights from Orlando to San Antonio
Ave. Duration
3h 5m
When
Monday and Friday
Estimated price
$120 - $550
Flights from Tampa to Austin
Ave. Duration
2h 45m
When
Tuesday, Thursday and Sunday
Estimated price
$100 - $450
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Lafayette Amtrak Station to San Antonio Amtrak Station
Ave. Duration
11h 41m
Frequency
3 times a week
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $170
Business Coach Seat
$130 - $180
Room
$290 - $410
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Myers, Fl to Tampa, Fl
Ave. Duration
3h 35m
Frequency
4 times a day
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45
Bus from Ft Myers, Fl to Port Charlotte, Fl
Ave. Duration
45m
Frequency
4 times a day
Estimated price
$10 - $21
Website
greyhound.com
Economy
$10 - $14
Flexible
$17 - $21
Bus from Austin, Tx to San Antonio, Tx
Ave. Duration
1h 30m
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Ft Myers, Fl to Orlando, Fl
Ave. Duration
6h 5m
Frequency
3 times a day
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Orlando, Fl to Houston, Tx
Ave. Duration
24h 15m
Frequency
Every 3 hours
Estimated price
$95 - $240
Website
greyhound.com
Economy
$95 - $160
Flexible
$180 - $240
Bus from Houston, Tx to San Antonio, Tx
Ave. Duration
3h 14m
Frequency
4 times a day
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Orlando, Fl to Lafayette, La
Ave. Duration
18h 35m
Frequency
5 times a day
Estimated price
$75 - $190
Website
greyhound.com
Economy
$75 - $130
Flexible
$140 - $190
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Port Charlotte,FL - Burger King to Orlando, FL - McDonalds
Ave. Duration
3h 10m
Frequency
Twice daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Fort Myers, FL - McDonalds to Fort Lauderdale – Hollywood International Airport
Ave. Duration
2h
Frequency
Twice daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Fort Myers, FL - McDonalds to Miami Airport
Ave. Duration
2h 50m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets

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More Questions & Answers

San Antonio is 1h behind Fort Myers. It is currently 8:33 AM in Fort Myers and 7:33 AM in San Antonio.

Yes, the driving distance between Fort Myers to San Antonio is 1306 miles. It takes approximately 21h 1m to drive from Fort Myers to San Antonio.

Get driving directions

United Airlines, Southwest Airlines, Delta and American Airlines offer flights from Ft. Myers Airport to San Antonio Airport.

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Book your Fort Myers to San Antonio bus tickets online with Greyhound, Greyhound and Greyhound.

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There are 428+ hotels available in San Antonio. Prices start at $52 USD per night.

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