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There are 7 ways to get from Fort Myers to Panama City by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus via Ocala  •  10h 40m

  1. Take the bus from Fort Myers, FL to Ocala, FL
  2. Take the bus from Ocala to Tallahassee Downtown
  3. Take the bus from Tallahassee, Fl to Panama City, Fl

$252 - $303

Cheapest option

Bus  •  13h 55m

  1. Take the bus from Ft Myers, Fl to Tallahassee, Fl 3752
  2. Take the bus from Tallahassee, Fl to Panama City, Fl 1243 / ...

$56 - $137

5 alternative options

Drive  •  8h 25m

  1. Drive from Fort Myers to Panama City 502.1 miles

$45 - $75

Fly Ft. Myers to Panama City  •  7h 9m

  1. Fly from Ft. Myers (RSW) to Panama City (ECP) RSW - ECP

$294 - $1,280

Fly Ft. Myers to Valparaiso, drive  •  8h 23m

  1. Fly from Ft. Myers (RSW) to Valparaiso (VPS) RSW - VPS
  2. Drive from Valparaiso to Panama City

$210 - $1,015

Fly Ft. Myers to Tallahassee, bus  •  8h 38m

  1. Fly from Ft. Myers (RSW) to Tallahassee (TLH) RSW - TLH
  2. Take the bus from Tallahassee, Fl to Panama City, Fl

$260 - $1,185

Bus to Tampa, fly to Tallahassee, bus  •  9h 11m

  1. Take the bus from Ft Myers, Fl to Tampa, Fl
  2. Fly from Tampa (TPA) to Tallahassee (TLH) TPA - TLH
  3. Take the bus from Tallahassee, Fl to Panama City, Fl

$167 - $547

Questions & Answers

The cheapest way to get from Fort Myers to Panama City is to drive which costs $45 - $75 and takes 8h 25m.

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The quickest way to get from Fort Myers to Panama City is to fly which costs $290 - $1,300 and takes 7h 9m.

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No, there is no direct bus from Fort Myers to Panama City. However, there are services departing from Ft Myers, Fl and arriving at Panama City, Fl via Tallahassee, Fl. The journey, including transfers, takes approximately 13h 55m.

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The distance between Fort Myers and Panama City is 339 miles. The road distance is 502.1 miles.

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The best way to get from Fort Myers to Panama City without a car is to bus which takes 10h 40m and costs $250 - $310.

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It takes approximately 10h 40m to get from Fort Myers to Panama City, including transfers.

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Fort Myers to Panama City bus services, operated by Greyhound USA, depart from Ft Myers, Fl station.

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The best way to get from Fort Myers to Panama City is to bus which takes 10h 40m and costs $250 - $310. Alternatively, you can fly, which costs $290 - $1,300 and takes 7h 9m.

Mode details

There is no direct flight from Ft. Myers Airport to Panama City Airport. The quickest flight takes 3h 43m and has one stopover.

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Fort Myers to Panama City bus services, operated by Greyhound USA, arrive at Panama City, Fl station.

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Map of how to get from Fort Myers to Panama City.
Launch map view
  • Distance: 339 miles
  • Duration: 10h 40m

What companies run services between Fort Myers, FL, USA and Panama City, FL, USA?

You can take a bus from Fort Myers to Panama City via Fort Myers, FL, Ocala, Tallahassee Downtown, and Tallahassee, Fl in around 10h 40m. Alternatively, Delta, American Airlines and three other airlines fly from Fort Myers to Panama City hourly.

Airlines
Delta
Website
delta.com
Flights from Ft. Myers to Panama City via Atlanta
Ave. Duration
4h 2m
When
Every day
Estimated price
$230 - $1,200
Flights from Ft. Myers to Panama City via Covington, Atlanta
Ave. Duration
7h 57m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$300 - $1,300
Flights from Ft. Myers to Valparaiso via Atlanta
Ave. Duration
4h 37m
When
Every day
Estimated price
$200 - $1,000
Flights from Ft. Myers to Tallahassee via Atlanta
Ave. Duration
4h 28m
When
Every day
Estimated price
$210 - $1,100
American Airlines
Website
aa.com
Flights from Ft. Myers to Panama City via Charlotte
Ave. Duration
5h 35m
When
Monday to Saturday
Estimated price
$270 - $1,200
Flights from Ft. Myers to Panama City via Dallas/Ft.Worth
Ave. Duration
6h 31m
When
Every day
Estimated price
$340 - $1,400
Flights from Ft. Myers to Panama City via Miami, Charlotte
Ave. Duration
8h 9m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$290 - $1,300
Flights from Ft. Myers to Valparaiso via Charlotte
Ave. Duration
4h 47m
When
Every day
Estimated price
$240 - $1,100
Flights from Ft. Myers to Valparaiso via Dallas/Ft.Worth
Ave. Duration
6h 30m
When
Every day
Estimated price
$300 - $1,200
Flights from Ft. Myers to Valparaiso via Miami, Charlotte
Ave. Duration
8h 27m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$260 - $1,100
Flights from Ft. Myers to Tallahassee via Miami
Ave. Duration
3h 17m
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
Flights from Ft. Myers to Tallahassee via Charlotte
Ave. Duration
6h 1m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
United Airlines
Website
united.com
Flights from Ft. Myers to Panama City via Houston
Ave. Duration
7h 38m
When
Every day
Estimated price
$320 - $1,400
Flights from Ft. Myers to Valparaiso via Houston
Ave. Duration
6h 51m
When
Every day
Estimated price
$280 - $1,200
Flights from Tampa to Tallahassee
Ave. Duration
1h 10m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $460
Southwest Airlines
Website
southwest.com
Flights from Ft. Myers to Panama City via St. Louis
Ave. Duration
6h 10m
When
Monday
Estimated price
$370 - $1,400
Flights from Ft. Myers to Panama City via Atlanta, Nashville
Ave. Duration
8h 10m
When
Monday to Friday
Estimated price
$310 - $1,200
Silver Airways
Website
silverairways.com
Flights from Tampa to Tallahassee
Ave. Duration
1h 10m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$100 - $460
Bus operators
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Fort Myers, FL to Ocala, FL
Ave. Duration
3h 35m
Frequency
Once daily
Estimated price
$159
Schedules at
lacubanabus.com
Red Coach
Phone
+1 877 733 0724
Email
webtickets@redcoachusa.com
Website
redcoachusa.com
Bus from Ocala to Tallahassee Downtown
Ave. Duration
3h 35m
Frequency
Every 4 hours
Estimated price
$45 - $65
Book at
redcoachusa.com
First Class
$55 - $80
Business
$45 - $65
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Tallahassee, Fl to Panama City, Fl
Ave. Duration
1h 15m
Frequency
Every 2 hours
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Ft Myers, Fl to Tallahassee, Fl
Ave. Duration
11h 40m
Frequency
Once daily
Estimated price
$40 - $100
Website
greyhound.com
Economy
$40 - $65
Flexible
$75 - $100
Bus from Ft Myers, Fl to Tampa, Fl
Ave. Duration
3h 35m
Frequency
4 times a day
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45

Want to know more about travelling around United States

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More Questions & Answers

Panama City is 1h behind Fort Myers. It is currently 2:54 PM in Fort Myers and 1:54 PM in Panama City.

Yes, the driving distance between Fort Myers to Panama City is 502 miles. It takes approximately 8h 25m to drive from Fort Myers to Panama City.

Get driving directions

United Airlines, Southwest Airlines, American Airlines and Delta offer flights from Ft. Myers Airport to Panama City Airport.

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Book your Fort Myers to Panama City bus tickets online with Greyhound and Greyhound.

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There are 924+ hotels available in Panama City. Prices start at $95 USD per night.

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