There are 8 ways to get from Fort Myers to Murrells Inlet by bus, plane, bus (Flixbus, Greyhound), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Tampa, fly to Myrtle Beach
best- Take the bus from Fort Myers 7-11 to Tampa International Airportbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
5h 35m$183–522Bus, train, drive
cheapest- Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus
- Take the train from Fort Lauderdale Amtrak Station to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
19h 35m$101–280Bus
- Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Florence Bus Stationbus
- Take the bus from Florence to Myrtle Beach, SCbus
18h 31m$152–338Drive 609.1 mi
- Drive from Fort Myers to Murrells Inletcar 609.1 mi
11h 21m$112–161Bus to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach
- Take the bus from Fort Myers Bus Stop to Fort Lauderdale International Airportbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane FLL - MYR
5h 26m$109–360Fly Ft. Myers to Myrtle Beach
- Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)plane RSW - MYR
7h 13m$284–805Fly Ft. Myers to Wilmington International Airport, bus
- Fly from Ft. Myers (RSW) to Wilmington International Airport (ILM)plane RSW - ILM
- Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus
7h 49m$180–628Bus, train
- Take the bus from Fort Myers Bus Stop to Orlandobus
- Take the train from Winter Park Amtrak Station to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
19h 36m$156–345
Tampa (TPA) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Fort Myers to Murrells Inlet is to drive which costs $110 - $170 and takes 11h 21m.
The fastest way to get from Fort Myers to Murrells Inlet is to bus and fly which takes 5h 26m and costs $100 - $360.
The distance between Fort Myers and Murrells Inlet is 602 miles. The road distance is 612.7 miles.
The best way to get from Fort Myers to Murrells Inlet without a car is to bus which takes 18h 31m and costs $150 - $340.
It takes approximately 5h 35m to get from Fort Myers to Murrells Inlet, including transfers.
The best way to get from Fort Myers to Murrells Inlet is to bus which takes 18h 31m and costs $150 - $340. Alternatively, you can fly, which costs $280 - $850 and takes 7h 13m.
Yes, the driving distance between Fort Myers to Murrells Inlet is 613 miles. It takes approximately 11h 21m to drive from Fort Myers to Murrells Inlet.
There are 2321+ hotels available in Murrells Inlet.
What companies run services between Fort Myers, FL, USA and Murrells Inlet, SC, USA?
You can take a bus from Fort Myers Bus Stop to Murrells Inlet via Orlando Bus Station, Florence Bus Station, Florence, and Myrtle Beach, SC in around 18h 31m. Alternatively, Delta, American Airlines, and Southwest Airlines fly from Ft. Myers (RSW) to Myrtle Beach (MYR) every 2 hours.
- Website
- aa.com
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $60–330
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $50–280
Flights from Ft. Myers to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $80–450
Flights from Ft. Myers to Wilmington International Airport via Charlotte
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $90–490
- Website
- delta.com
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $60–340
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $55–300
Flights from Ft. Myers to Myrtle Beach via Atlanta
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $85–460
Flights from Ft. Myers to Wilmington International Airport via Atlanta
- Ave. Duration
- 4h 52m
- When
- Saturday
- Estimated price
- $100–550
- Website
- flybreeze.com
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 38m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–250
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach
- Ave. Duration
- 1h 45m
- When
- Monday and Friday
- Estimated price
- $100–550
Flights from Ft. Myers to Wilmington International Airport
- Ave. Duration
- 1h 57m
- When
- Monday and Friday
- Estimated price
- $190–950
- Website
- southwest.com
Flights from Ft. Myers to Myrtle Beach via Baltimore
- Ave. Duration
- 5h 45m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Ft. Myers to Myrtle Beach via Nashville
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $110–550
- Website
- spirit.com
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach
- Ave. Duration
- 1h 45m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–240
- Website
- aveloair.com
Flights from Ft. Myers to Wilmington International Airport
- Ave. Duration
- 1h 57m
- When
- Monday and Friday
- Estimated price
- $160–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fort Lauderdale Amtrak Station to Kingstree Station
- Ave. Duration
- 13h 35m
- Frequency
- Once daily
- Estimated price
- $65–220
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $65–170
- Coach Seat short notice purchase
- $90–220
- Business - advance purchase
- $120–500
- Business Class
- $200–490
Train from Winter Park Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 7h 32m
- Frequency
- Once daily
- Estimated price
- $65–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Myers 7-11 to Tampa International Airport
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a week
- Estimated price
- $23–140
- Website
- https://www.redcoachusa.com
- Web
- $23–140
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Fort Myers Bus Stop to Orlando Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- 4 times a day
- Estimated price
- $30–50
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Florence Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Once daily
- Estimated price
- $60–140
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Station
- Ave. Duration
- 2h 45m
- Frequency
- Twice daily
- Estimated price
- $23–40
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Fort Lauderdale International Airport
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $23–50
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Orlando
- Ave. Duration
- 5h 50m
- Frequency
- 3 times a day
- Estimated price
- $30–75
- Schedules at
- flixbus.com
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $14–18
- Website
- https://www.greyhound.com/
Bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $27–60
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide












