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There are 5 ways to get from Fort Myers to Mayo Clinic Hospital by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, train  •  10h 42m

  1. Take the bus from Ft Myers, Fl to Port Charlotte, Fl
  2. Take the bus from Port Charlotte,FL - Burger King to Tampa, FL - McDonalds 301 / ...
  3. Take the train from Tampa Union Station to Jacksonville Amtrak Station

$149 - $289

4 alternative options

Amtrak Thruway, train, bus  •  11h 59m

  1. Take the Amtrak Thruway from Fort Myers, FL to Orlando, FL
  2. Take the train from Orlando Health/Amtrak to DeBary
  3. Take the bus from Deltona, FL to Jacksonville, FL

Drive  •  5h 27m

  1. Drive from Fort Myers to Mayo Clinic Hospital 292.9 miles

$28 - $45

Fly to Gainesville, drive  •  8h 14m

  1. Fly from Ft. Myers (RSW) to Gainesville (GNV) RSW - GNV
  2. Drive from Gainesville to Mayo Clinic Hospital

$242 - $1,217

Line 140 bus, fly to Jacksonville, bus, line 303 bus  •  10h 21m

  1. Take the line 140 bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
  2. Fly from Ft. Myers (RSW) to Jacksonville (JAX) RSW - JAX
  3. Take the bus from Rosa Parks Station Bay M to 3rd Ave. S. & 3rd St.
  4. Take the line 303 bus from 3rd Ave. S. & 3rd St. to Mellish Dr. & Zumbro Dr.fs

$156 - $761

Questions & Answers

The cheapest way to get from Fort Myers to Mayo Clinic Hospital is to drive which costs $28 - $45 and takes 5h 27m.

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The quickest way to get from Fort Myers to Mayo Clinic Hospital is to drive which costs $28 - $45 and takes 5h 27m.

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The distance between Fort Myers and Mayo Clinic Hospital is 254 miles. The road distance is 292.9 miles.

Get driving directions

The best way to get from Fort Myers to Mayo Clinic Hospital without a car is to bus and train which takes 10h 42m and costs $140 - $290.

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It takes approximately 10h 42m to get from Fort Myers to Mayo Clinic Hospital, including transfers.

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There is no direct flight from Ft. Myers Airport to Gainesville Airport. The quickest flight takes 3h 45m and has one stopover.

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Yes, the driving distance between Fort Myers to Mayo Clinic Hospital is 293 miles. It takes approximately 5h 27m to drive from Fort Myers to Mayo Clinic Hospital.

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Delta and American Airlines offer flights from Ft. Myers Airport to Gainesville Airport.

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There are 143+ hotels available in Mayo Clinic Hospital. Prices start at $79 USD per night.

More details

Map of how to get from Fort Myers to Mayo Clinic Hospital.
Launch map view
  • Distance: 254.2 miles
  • Duration: 10h 42m

What companies run services between Fort Myers, FL, USA and Mayo Clinic Hospital, FL, USA?

There is no direct connection from Fort Myers to Mayo Clinic Hospital. However, you can take the bus to Port Charlotte, Fl, take the walk to Port Charlotte,FL - Burger King, take the bus to Tampa, FL - McDonalds, take the walk to Palm Av @ 20th St, take the line 12 bus to Nebraska Av @ Cass St, take the walk to Tampa Union Station, take the train to Jacksonville Amtrak Station, then take the taxi to Mayo Clinic Hospital. Alternatively, you can take a vehicle from Fort Myers to Mayo Clinic Hospital via Orlando, FL, Orlando Health/Amtrak, DeBary, Debary Sunrail Station, Park N' Ride Saxon 0b, Deltona, FL, and Jacksonville, FL in around 11h 59m.

Airlines
American Airlines
Website
aa.com
Flights from Ft. Myers to Gainesville via Charlotte
Ave. Duration
4h 51m
When
Every day
Estimated price
$300 - $1,300
Flights from Ft. Myers to Gainesville via Miami
Ave. Duration
8h
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,200
Flights from Ft. Myers to Gainesville via Miami, Charlotte
Ave. Duration
8h 11m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$310 - $1,400
Flights from Ft. Myers to Gainesville via Reagan Washington, Charlotte
Ave. Duration
8h 17m
When
Monday, Wednesday, Thursday and Friday
Estimated price
$360 - $1,500
Flights from Ft. Myers to Jacksonville via Miami
Ave. Duration
4h 11m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$150 - $750
Flights from Ft. Myers to Jacksonville via Charlotte
Ave. Duration
4h 31m
When
Every day
Estimated price
$180 - $850
Flights from Ft. Myers to Jacksonville via Dallas/Ft.Worth
Ave. Duration
6h 30m
When
Every day
Estimated price
$250 - $1,000
Delta
Website
delta.com
Flights from Ft. Myers to Gainesville via Atlanta
Ave. Duration
4h 36m
When
Every day
Estimated price
$260 - $1,300
Flights from Ft. Myers to Jacksonville via Atlanta
Ave. Duration
4h 7m
When
Every day
Estimated price
$160 - $800
Flights from Ft. Myers to Jacksonville via Detroit
Ave. Duration
6h 23m
When
Every day
Estimated price
$230 - $1,000
Southwest Airlines
Website
southwest.com
Flights from Ft. Myers to Jacksonville via Atlanta
Ave. Duration
4h 5m
When
Saturday
Estimated price
$190 - $800
Flights from Ft. Myers to Jacksonville via Baltimore
Ave. Duration
5h 57m
When
Saturday and Sunday
Estimated price
$260 - $950
Flights from Ft. Myers to Jacksonville via Dallas
Ave. Duration
6h 30m
When
Monday to Friday
Estimated price
$280 - $1,000
Flights from Ft. Myers to Jacksonville via Chicago Midway
Ave. Duration
6h 37m
When
Monday to Saturday
Estimated price
$290 - $1,100
United Airlines
Website
united.com
Flights from Ft. Myers to Jacksonville via Houston
Ave. Duration
6h 9m
When
Every day
Estimated price
$240 - $1,000
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Tampa Union Station to Jacksonville Amtrak Station
Ave. Duration
5h 16m
Frequency
Once daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$80 - $120
Business Coach Seat
$80 - $120
Room
$210 - $300
SunRail
Website
sunrail.com
Train from Orlando Health/Amtrak to DeBary
Ave. Duration
56m
Frequency
Hourly
Estimated price
$3 - $4
Schedules at
sunrail.com
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Myers, Fl to Port Charlotte, Fl
Ave. Duration
45m
Frequency
4 times a day
Estimated price
$10 - $21
Website
greyhound.com
Economy
$10 - $14
Flexible
$17 - $21
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Port Charlotte,FL - Burger King to Tampa, FL - McDonalds
Ave. Duration
1h 55m
Frequency
Twice daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Fort Myers, FL to Orlando, FL
Ave. Duration
5h 50m
Frequency
Once daily
Website
amtrak.com
bus
Bus from Deltona, FL to Jacksonville, FL
Ave. Duration
2h
Frequency
5 times a week
Schedules at
lacubanabus.com
Lee County Transit
Phone
+1 239-533-2111
Website
rideleetran.com
Bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
Ave. Duration
25m
Frequency
Every 30 minutes
Estimated price
$1 - $3
Schedules at
leegov.com
Jacksonville Transport
Phone
+1 904-630-3100
Website
jtafla.com
Bus from Rosa Parks Station Bay M to 3rd Ave. S. & 3rd St.
Ave. Duration
1h 9m
Frequency
Every 15 minutes
Estimated price
$1 - $2
Schedules at
jtafla.com
Bus from 3rd Ave. S. & 3rd St. to Mellish Dr. & Zumbro Dr.fs
Ave. Duration
30m
Frequency
Every 4 hours
Estimated price
$1 - $2
Schedules at
jtafla.com

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