There are 6 ways to get from Fort Myers to Key Largo by bus (Flixbus, Greyhound), car, bus, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Fort Myers Bus Stop to Miami Airport StationFlixBus 2421
- Take the bus from Miami Airport Station to Key Largo Bus StopGreyhound US0720s
5h 35m$39–71Drive 176.7 mi
cheapest- Drive from Fort Myers to Key Largo176.7 mi
3h 32m$33–47Bus to Tampa, fly, shuttle
- Take the bus from Fort Myers 7-11 to Tampa International Airport
- Fly from Tampa (TPA) to Miami International Airport (MIA)TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 55m$205–527Bus via Pembroke Pines
- Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail StationFlixBus 2421
- Take the bus from Miami Airport Station to Key Largo Bus StopGreyhound US0720s
6h 21m$40–68Bus via Homestead
- Take the bus from Fort Myers to Miami
- Take the bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ride38 / ...
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo301
7h 31mFly from Ft. Myers, shuttle
- Fly from Ft. Myers (RSW) to Miami International Airport (MIA)RSW - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 30m$138–455
Fort Myers to Key Largo by bus
Questions & Answers
The cheapest way to get from Fort Myers to Key Largo is to drive which costs $30 - $50 and takes 3h 32m.
The fastest way to get from Fort Myers to Key Largo is to drive which takes 3h 32m and costs $30 - $50.
No, there is no direct bus from Fort Myers to Key Largo. However, there are services departing from Fort Myers Bus Stop and arriving at Key Largo Bus Stop via Miami Airport Station. The journey, including transfers, takes approximately 5h 35m.
The distance between Fort Myers and Key Largo is 218 miles. The road distance is 177.7 miles.
The best way to get from Fort Myers to Key Largo without a car is to bus which takes 5h 35m and costs $35 - $75.
It takes approximately 5h 35m to get from Fort Myers to Key Largo, including transfers.
Fort Myers to Key Largo bus services, operated by Flixbus USA, depart from Fort Myers Bus Stop station.
Fort Myers to Key Largo bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Fort Myers to Key Largo is 178 miles. It takes approximately 3h 32m to drive from Fort Myers to Key Largo.
Book your Fort Myers to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Fort Myers, FL, USA and Key Largo, FL, USA?
You can take a bus from Fort Myers Bus Stop to Key Largo Bus Stop via Miami Airport Station in around 5h 35m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $30–230
Flights from Ft. Myers to Miami International Airport via Charlotte
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $110–550
- Website
- delta.com
Flights from Ft. Myers to Miami International Airport via Atlanta
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Ft. Myers to Miami International Airport via Orlando
- Ave. Duration
- 4h 20m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $55–340
- Website
- flyfrontier.com
Flights from Ft. Myers to Miami International Airport via Atlanta
- Ave. Duration
- 7h 1m
- When
- Monday and Friday
- Estimated price
- $100–550
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Fort Myers Bus Stop to Miami Airport Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $26–50
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Station
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $13–23
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Myers 7-11 to Tampa International Airport
- Ave. Duration
- 2h 20m
- Frequency
- 5 times a week
- Estimated price
- $15–65
- Website
- https://www.redcoachusa.com
- Web
- $15–65
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Fort Myers to Miami
- Ave. Duration
- 3h 36m
- Frequency
- Once daily
- Estimated price
- $50–70
- Schedules at
- omnibusexpress.com
- Phone
- +1 786-469-5675
- Website
- miamidade.gov
Bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ride
- Ave. Duration
- 1h 12m
- Frequency
- Every 15 minutes
- Website
- https://www.miamidade.gov/global/transportation/home.page
Bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Website
- https://www.miamidade.gov/global/transportation/home.page
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 285+ hotels available in Key Largo.















