There are 5 ways to get from Fort Myers to Key Largo by bus, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus Javax Bus  •  5 h 53 min

  1. Take the bus from Fort Myers, FL to Miami Airport Javax Bus
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$71 - $112

Cheapest option

Bus Greyhound USA  •  9 h 2 min

  1. Take the bus from Ft Myers, Fl to Miami, Fl 3749 / ...
  2. Take the bus from W Palm Dr & 3 Av to Mile Marker 98 Key Largo 301

$34 - $68

3 alternative options

Drive  •  3 h 33 min

  1. Drive from Fort Myers to Key Largo 201.4 miles

$19 - $29

Line 140 bus to Ft. Myers, fly, shuttle  •  5 h 53 min

  1. Take the line 140 bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
  2. Fly from Ft. Myers (RSW) to Miami (MIA) RSW - MIA
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$174 - $725

Bus to Orlando, fly, shuttle  •  8 h 27 min

  1. Take the bus from Fort Myers - Walmart to Orlando Airport
  2. Fly from Orlando (MCO) to Miami (MIA) MCO - MIA
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$169 - $439

Questions & Answers

The distance between Fort Myers and Key Largo is 138 miles. The road distance is 201.4 miles.

Get driving directions

The best way to get from Fort Myers to Key Largo without a car is to bus which takes 5 h 53 min and costs .

More details

It takes approximately 5 h 53 min to get from Fort Myers to Key Largo, including transfers.

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The quickest flight from Ft. Myers Airport to Miami Airport is the direct flight which takes 48 min.

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Yes, the driving distance between Fort Myers to Key Largo is 201 miles. It takes approximately 3 h 33 min to drive from Fort Myers to Key Largo.

Get driving directions

American Airlines offers flights from Ft. Myers Airport to Miami Airport.

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There are 67+ hotels available in Key Largo. Prices start at $115 USD per night.

More details

Map of how to get from Fort Myers to Key Largo.
Launch map view
  • Distance: 137.7 miles
  • Duration: 5 h 53 min

What companies run services between Fort Myers, FL, USA and Key Largo, FL, USA?

You can take a bus from Fort Myers to Key Largo via Miami Airport, Mia@Lower Level Ramp, Airport Station, Nw 42 Av & Nw 11 St, and Miami, FL - Airport Regency Hotel in around 5 h 53 min.

Airlines
American Airlines
Website
aa.com
Flights from Ft. Myers to Miami
Ave. Duration
48 min
When
Every day
Estimated price
$110 - $650
Flights from Orlando to Miami
Ave. Duration
1 h 11 min
When
Every day
Estimated price
$85 - $600
Delta
Website
delta.com
Flights from Orlando to Miami
Ave. Duration
58 min
When
Every day
Estimated price
$60 - $480
Bus operators
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from Fort Myers, FL to Miami Airport
Ave. Duration
2 h 25 min
Frequency
Every 3 hours
Estimated price
$40 - $50
Schedules at
javaxbus.com
Book at
gotobus.com
Bus from Fort Myers - Walmart to Orlando Airport
Ave. Duration
4 h 15 min
Frequency
3 times a day
Estimated price
$49
Schedules at
javaxbus.com
Book at
gotobus.com
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Miami, FL - Airport Regency Hotel to Key Largo, FL
Ave. Duration
1 h 30 min
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Myers, Fl to Miami, Fl
Ave. Duration
5 h 25 min
Frequency
Every 30 minutes
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Lee County Transit
Phone
+1 239-533-2111
Website
rideleetran.com
Bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
Ave. Duration
25 min
Frequency
Every 30 minutes
Estimated price
$1 - $3
Schedules at
leegov.com
Keys Shuttle
Phone
+1 (888) 765-9997 | (305) 289-9997
Website
keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
Ave. Duration
1 h 15 min
Frequency
5 times a day
Estimated price
$60 - $70
Schedules at
keysshuttle.com

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