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There are 7 ways to get from Fort Myers to Key Largo by bus, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus La Cubana  •  6h 35m

  1. Take the bus from Fort Myers, FL to Hialeah, FL Atlanta route
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$216 - $253

Cheapest option

Bus Greyhound USA #2  •  9h 1m

  1. Take the bus from Ft Myers, Fl to Miami, Fl 3749 / ...
  2. Take the bus from W Palm Dr & 3 Av to Mile Marker 98 Key Largo 301

$34 - $68

5 alternative options

Bus Greyhound USA  •  8h 34m

  1. Take the bus from Ft Myers, Fl to Miami, Fl 3749 / ...
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$55 - $122

Bus via Daniels Parkway @ Danport Boulevard  •  8h 34m

  1. Take the bus from Fort Myers, FL - McDonalds to Miami Airport 303
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key Largo, FL 400

$60 - $129

Drive  •  3h 33m

  1. Drive from Fort Myers to Key Largo 201.4 miles

$19 - $29

Line 140 bus to Ft. Myers, fly, shuttle  •  5h 52m

  1. Take the line 140 bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
  2. Fly from Ft. Myers (RSW) to Miami (MIA) RSW - MIA
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$174 - $725

Bus to Tampa, fly, shuttle  •  8h 49m

  1. Take the bus from Ft Myers, Fl to Tampa, Fl
  2. Fly from Tampa (TPA) to Miami (MIA) TPA - MIA
  3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL

$141 - $367

Questions & Answers

The cheapest way to get from Fort Myers to Key Largo is to drive which costs $19 - $29 and takes 3h 33m.

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The quickest way to get from Fort Myers to Key Largo is to drive which costs $19 - $29 and takes 3h 33m.

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No, there is no direct bus from Fort Myers to Key Largo. However, there are services departing from Ft Myers, Fl and arriving at Key Largo, FL via Airport Station and Miami, FL - Airport Regency Hotel. The journey, including transfers, takes approximately 8h 34m.

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The distance between Fort Myers and Key Largo is 138 miles. The road distance is 201.4 miles.

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The best way to get from Fort Myers to Key Largo without a car is to bus which takes 6h 35m and costs $210 - $260.

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It takes approximately 6h 35m to get from Fort Myers to Key Largo, including transfers.

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Fort Myers to Key Largo bus services, operated by Greyhound USA, depart from Ft Myers, Fl station.

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The quickest flight from Ft. Myers Airport to Miami Airport is the direct flight which takes 47m.

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Fort Myers to Key Largo bus services, operated by The Florida Express Bus, arrive at Key Largo, FL station.

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Yes, the driving distance between Fort Myers to Key Largo is 201 miles. It takes approximately 3h 33m to drive from Fort Myers to Key Largo.

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Map of how to get from Fort Myers to Key Largo.
Launch map view
  • Distance: 137.7 miles
  • Duration: 6h 35m

What companies run services between Fort Myers, FL, USA and Key Largo, FL, USA?

You can take a bus from Fort Myers to Key Largo via Fort Myers, FL, Hialeah, FL, W 12 Av & W 42 St, Okeechobee Metrorail Station, Okeechobee Station Rail Southbound, Earlington Hts.Stat.Rail Northbound, Miami International Airport Station Northbound, Airport Station, Nw 42 Av & Nw 11 St, and Miami, FL - Airport Regency Hotel in around 6h 35m.

Airlines
American Airlines
Website
aa.com
Flights from Ft. Myers to Miami
Ave. Duration
47m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$110 - $650
Flights from Tampa to Miami
Ave. Duration
1h 8m
When
Every day
Estimated price
$65 - $360
Bus operators
La Cubana
Phone
+1 305-541-1700
Website
lacubanabus.com
Bus from Fort Myers, FL to Hialeah, FL
Ave. Duration
2h 18m
Frequency
3 times a week
Estimated price
$159
Schedules at
lacubanabus.com
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Miami, FL - Airport Regency Hotel to Key Largo, FL
Ave. Duration
1h 30m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Fort Myers, FL - McDonalds to Miami Airport
Ave. Duration
2h 50m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Myers, Fl to Miami, Fl
Ave. Duration
5h 25m
Frequency
5 times a day
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Bus from Ft Myers, Fl to Tampa, Fl
Ave. Duration
3h 35m
Frequency
4 times a day
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$35 - $45
Lee County Transit
Phone
+1 239-533-2111
Website
rideleetran.com
Bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
Ave. Duration
25m
Frequency
Every 30 minutes
Estimated price
$1 - $3
Schedules at
leegov.com
Keys Shuttle
Phone
+1 (888) 765-9997 | (305) 289-9997
Website
keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
Ave. Duration
1h 15m
Frequency
5 times a day
Estimated price
$60 - $70
Schedules at
keysshuttle.com

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American Airlines offers flights from Ft. Myers Airport to Miami Airport.

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There are 66+ hotels available in Key Largo. Prices start at $119 USD per night.

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