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How to get fromFort Myers to Key Largoby bus (Flixbus, Greyhound), car, plane, shuttle, or bus

Find Transport to Key Largo

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There are 6 ways to get from Fort Myers to Key Largo by bus (Flixbus, Greyhound), car, plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Fort Myers Bus Stop to Miami Airport Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    5h 25m
    $33–51

  2. Drive  176.6 mi

    1. Drive from Fort Myers to Key Largocar car 176.6 mi
    3h 33m
    $33–47

  3. Fly from Ft. Myers, shuttle

    1. Fly from Ft. Myers (RSW) to Miami International Airport (MIA)plane plane RSW - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    9h
    $158–515

  4. Bus via Pembroke Pines

    1. Take the bus from Fort Myers Bus Stop to Hollywood Sheridan Trirail Stationbus bus FlixBus 2421
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    6h 21m
    $33–52

  5. Bus, line 602 bus

    1. Take the bus from Fort Myers to Miamibus bus
    2. Take the bus from Dadeland South Metrorail Station to Sw 344 St Park-And-Ridebus bus 602 / ...
    3. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    7h 38m
    $66–79

  6. Bus to Sarasota–Bradenton International Airport, fly, shuttle

    1. Take the bus from Fort Myers Bus Stop to Sarasota Cattlemen Transfer Centerbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Miami International Airport (MIA)plane plane SRQ - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Key Largo, FLshuttle bus
    7h 1m
    $177–610

Fort Myers to Key Largo by bus

Calendar19Weekly Buses
Duration5h 25mAverage Duration
Ticket$33Cheapest Price
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Comparing Your Travel Options

Map of how to get from Fort Myers to Key Largo.ExpandLaunch map view
  • Distance: 216.3 mi
  • Duration: 5h 25m

What companies run services between Fort Myers, FL, USA and Key Largo, FL, USA?

You can take a bus from Fort Myers Bus Stop to Key Largo Bus Stop via Miami Airport Station in around 5h 25m.

Airlines
Bus operators

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