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There are 8 ways to get from Fort Myers to Isla Mujeres by car, ferry, bus or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Drive, ferry  •  2 days 7h

  1. Drive from Fort Myers to Playa Tortugas
  2. Take the ferry from Playa Tortugas to Isla Mujeres

$402 - $575

Cheapest option

Fly Ft. Myers to Cancun, ferry  •  11h 16m

  1. Fly from Ft. Myers (RSW) to Cancun (CUN) RSW - CUN
  2. Take the ferry from Puerto Juárez to Isla Mujeres

$136 - $1,035

6 alternative options

Ferry, drive  •  2 days 18h

  1. Take the ferry from Fort Myers Beach, FL to Key West, FL
  2. Take the ferry from Key West, FL to Marco Island, FL
  3. Drive from Marco Island, FL to Playa Tortugas
  4. Take the ferry from Playa Tortugas to Isla Mujeres

$596 - $808

Bus, ferry, drive  •  3 days 0h

  1. Take the bus from Ft Myers, Fl to Miami, Fl
  2. Take the bus from Miami, FL - Airport Regency Hotel to Key West, FL - Mel Fisher Museum 400
  3. Take the ferry from Key West, FL to Marco Island, FL
  4. Drive from Marco Island, FL to Playa Tortugas
  5. Take the ferry from Playa Tortugas to Isla Mujeres

$554 - $831

Fly Ft. Myers to Cozumel, ferry, bus  •  13h 19m

  1. Fly from Ft. Myers (RSW) to Cozumel (CZM) RSW - CZM
  2. Take the ferry from Cozumel to Playa del Carmen
  3. Take the bus from Playa del Carmen to Cancún
  4. Take the ferry from Puerto Juárez to Isla Mujeres

$188 - $1,430

Bus to Fort Lauderdale, fly to Cancun, ferry  •  10h 28m

  1. Take the bus from Fort Myers, FL - McDonalds to Fort Lauderdale – Hollywood International Airport
  2. Fly from Fort Lauderdale (FLL) to Cancun (CUN) FLL - CUN
  3. Take the ferry from Puerto Juárez to Isla Mujeres

$152 - $646

Bus to Miami, fly to Cancun, ferry  •  11h 15m

  1. Take the bus from Fort Myers, FL - McDonalds to Miami Airport
  2. Fly from Miami (MIA) to Cancun (CUN) MIA - CUN
  3. Take the ferry from Puerto Juárez to Isla Mujeres

$152 - $556

Bus, bus to Orlando, fly to Cancun, ferry  •  12h 27m

  1. Take the bus from Ft Myers, Fl to Port Charlotte, Fl
  2. Take the bus from Port Charlotte,FL - Burger King to Orlando, FL - McDonalds
  3. Fly from Orlando (MCO) to Cancun (CUN) MCO - CUN
  4. Take the ferry from Puerto Juárez to Isla Mujeres

$162 - $544

Questions & Answers

The cheapest way to get from Fort Myers to Isla Mujeres is to bus and fly and ferry which costs $150 - $600 and takes 11h 15m.

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The quickest way to get from Fort Myers to Isla Mujeres is to bus and fly and ferry which costs $150 - $650 and takes 10h 28m.

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The distance between Fort Myers and Isla Mujeres is 486 miles.

It takes approximately 2 days 7h to get from Fort Myers to Isla Mujeres, including transfers.

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There is no direct flight from Ft. Myers Airport to Cancun Airport. The quickest flight takes 5h 25m and has one stopover.

Search flights

Spirit Airlines, Air Canada, United Airlines and three other airlines offer flights from Ft. Myers Airport to Cancun Airport.

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There are 1250+ hotels available in Isla Mujeres. Prices start at $32 USD per night.

More details

Map of how to get from Fort Myers to Isla Mujeres.
Launch map view
  • Distance: 485.8 miles
  • Duration: 2 days 7h

What companies run services between Fort Myers, FL, USA and Isla Mujeres, Quintana Roo, Mexico?

There is no direct connection from Fort Myers to Isla Mujeres. However, you can take the drive to Playa Tortugas then take the ferry to Isla Mujeres. Alternatively, you can take the line 130 bus to Beach Park & Ride, take the drive to Fort Myers Beach, FL, take the ferry to Key West, FL, take the ferry to Marco Island, FL, take the drive to Playa Tortugas, then take the ferry to Isla Mujeres.

Airlines
American Airlines
Website
aa.com
Flights from Ft. Myers to Cancun via Miami
Ave. Duration
6h 3m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$120 - $1,000
Flights from Ft. Myers to Cancun via Charlotte
Ave. Duration
6h 17m
When
Every day
Estimated price
$220 - $1,400
Flights from Ft. Myers to Cancun via Dallas/Ft.Worth
Ave. Duration
7h 34m
When
Every day
Estimated price
$260 - $1,600
Flights from Ft. Myers to Cancun via Philadelphia
Ave. Duration
8h 2m
When
Every day
Estimated price
$300 - $1,700
Flights from Ft. Myers to Cancun via Chicago O'Hare
Ave. Duration
7h 58m
When
Sunday
Estimated price
$310 - $1,800
Flights from Ft. Myers to Cozumel via Miami
Ave. Duration
5h 53m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$170 - $1,400
Flights from Ft. Myers to Cozumel via Charlotte
Ave. Duration
6h 56m
When
Saturday
Estimated price
$300 - $1,900
Flights from Ft. Myers to Cozumel via Dallas/Ft.Worth
Ave. Duration
9h 48m
When
Monday to Saturday
Estimated price
$350 - $2,100
Flights from Miami to Cancun
Ave. Duration
1h 52m
When
Every day
Estimated price
$130 - $650
Flights from Orlando to Cancun via Miami
Ave. Duration
4h 26m
When
Every day
Estimated price
$150 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Ft. Myers to Cancun via St. Louis
Ave. Duration
6h 40m
When
Sunday
Estimated price
$290 - $1,100
Flights from Ft. Myers to Cancun via Atlanta
Ave. Duration
7h 35m
When
Monday to Saturday
Estimated price
$230 - $900
Flights from Ft. Myers to Cancun via Baltimore
Ave. Duration
8h 27m
When
Monday to Saturday
Estimated price
$300 - $1,100
Flights from Ft. Myers to Cancun via Chicago Midway
Ave. Duration
9h 25m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,100
Flights from Fort Lauderdale to Cancun
Ave. Duration
2h 3m
When
Every day
Estimated price
$150 - $650
Flights from Orlando to Cancun via Fort Lauderdale
Ave. Duration
4h 23m
When
Every day
Estimated price
$160 - $650
Delta
Website
delta.com
Flights from Ft. Myers to Cancun via Atlanta
Ave. Duration
6h 1m
When
Every day
Estimated price
$230 - $1,500
Flights from Ft. Myers to Cozumel via Atlanta
Ave. Duration
7h 34m
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$320 - $2,100
Flights from Orlando to Cancun
Ave. Duration
2h 4m
When
Every day
Estimated price
$170 - $1,100
United Airlines
Website
united.com
Flights from Ft. Myers to Cancun via Houston
Ave. Duration
8h 24m
When
Every day
Estimated price
$240 - $1,400
Flights from Ft. Myers to Cancun via Newark
Ave. Duration
8h 50m
When
Saturday
Estimated price
$350 - $1,700
Flights from Ft. Myers to Cozumel via Houston
Ave. Duration
8h 20m
When
Wednesday and Saturday
Estimated price
$330 - $1,900
Spirit Airlines
Website
spirit.com
Flights from Ft. Myers to Cancun via Detroit
Ave. Duration
9h
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$300 - $900
Flights from Fort Lauderdale to Cancun
Ave. Duration
1h 59m
When
Every day
Estimated price
$150 - $650
JetBlue Airways
Website
jetblue.com
Flights from Fort Lauderdale to Cancun
Ave. Duration
1h 52m
When
Every day
Estimated price
$160 - $750
Flights from Orlando to Cancun
Ave. Duration
2h 2m
When
Every day
Estimated price
$170 - $850
Air Canada
Website
aircanada.com
Flights from Ft. Myers to Cancun via Toronto
Ave. Duration
9h 10m
When
Every day
Estimated price
$450 - $2,300
Sunwing Airlines
Website
sunwing.ca
Flights from Ft. Myers to Cozumel via Toronto
Ave. Duration
8h 30m
When
Friday
Estimated price
$600 - $2,000
Air Transat
Website
airtransat.com
Flights from Ft. Myers to Cozumel via Toronto
Ave. Duration
8h 45m
When
Saturday
Estimated price
$550 - $1,900
LATAM Chile
Website
latam.com
Flights from Miami to Cancun
Ave. Duration
1h 55m
When
Friday and Saturday
Estimated price
$480 - $3,000
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Myers, Fl to Miami, Fl
Ave. Duration
5h 25m
Frequency
5 times a day
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Bus from Ft Myers, Fl to Port Charlotte, Fl
Ave. Duration
45m
Frequency
4 times a day
Estimated price
$10 - $21
Website
greyhound.com
Economy
$10 - $14
Flexible
$17 - $21
The Florida Express Bus
Phone
407-442-2810
Website
busticketreservations.com
Bus from Miami, FL - Airport Regency Hotel to Key West, FL - Mel Fisher Museum
Ave. Duration
4h
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Fort Myers, FL - McDonalds to Fort Lauderdale – Hollywood International Airport
Ave. Duration
2h
Frequency
Twice daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Fort Myers, FL - McDonalds to Miami Airport
Ave. Duration
2h 50m
Frequency
Once daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Bus from Port Charlotte,FL - Burger King to Orlando, FL - McDonalds
Ave. Duration
3h 10m
Frequency
Twice daily
Estimated price
$27 - $60
More information at
American Bus Tickets
Transporte Foráneo Cancún-Playa del Carmen
Phone
(52) 998 8886990
Website
taxistascancun.com
Bus from Playa del Carmen to Cancún
Ave. Duration
1h 15m
Frequency
Every 10 minutes
Estimated price
$2 - $3
Schedules at
taxistascancun.com
Ferry operators
Ultramar Ferry
Phone
01 998 881 5890
Email
info@ultramar.com
Website
ultramarferry.com
Ferry from Playa Tortugas to Isla Mujeres
Ave. Duration
30m
Frequency
Every 2 hours
Estimated price
$14
Schedules at
ultramarferry.com
Ferry from Puerto Juárez to Isla Mujeres
Ave. Duration
30m
Frequency
Every 30 minutes
Estimated price
$9
Schedules at
ultramarferry.com
Ferry from Cozumel Port to Playa del Carmen Ultramar Ferry Port
Ave. Duration
40m
Frequency
Hourly
Estimated price
$3 - $12
Schedules at
ultramarferry.com
Premium Plus
$9
First Class
$12
Plan Peninsular (Residentes en Yucatán, Campeche)
$6
Plan Quintana Roo (Residentes Q.Roo)
$4
Key West Express
Phone
+1 239-463-5733
Website
keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
Ave. Duration
3h 30m
Frequency
Once daily
Estimated price
$95
Book at
Key West Express
Ferry from Key West, FL to Marco Island, FL
Ave. Duration
2h 30m
Frequency
Twice a week
Estimated price
$95
Book at
Key West Express
Mexico Waterjets
Phone
9878721588
Email
datos@mexicowaterjets.com.mx
Website
winjet.mx
Ferry from Cozumel to Playa del Carmen
Ave. Duration
40m
Frequency
Hourly
Estimated price
$2 - $9
Schedules at
winjet.mx
Book at
winjet.mx
Regular
$9
Local
$3
Barcos Caribe
Phone
01 987 120 3982
Email
contacto@barcoscaribe.com
Website
barcoscaribe.com
Ferry from Cozumel to Playa del Carmen
Ave. Duration
40m
Frequency
Hourly
Estimated price
$3 - $7
Schedules at
barcoscaribe.com
Book at
barcoscaribe.com
ADULT
$7
Quintana Roo Residents
$4
Yucatan Peninsula Residents
$6

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