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How to get fromFlorida to St. Louisby plane, bus (Flixbus, Greyhound), car, train or bus (Greyhound, Flixbus)

Find Transport to St. Louis

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There are 10 ways to get from Florida to St. Louis by plane, bus (Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Jacksonville to Lambert–St. Louis International Airport

    best
    1. Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)planeJAX - STL
    4h 58m
    $155–856

  2. Fly Saint Petersburg–Clearwater International Airport to Midamerica St. Louis Airport, train

    cheapest
    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Midamerica St. Louis Airport (BLV)planePIE - BLV
    2. Take the train from SHILOH-SCOTT station to CIVIC CENTER stationtrain
    5h 45m
    $103–434

  3. Bus

    1. Take the bus from Jacksonville to Atlanta Bus StationbusFlixBus 2434 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus StationbusFlixBus N2521
    18h 20m
    $118–302

  4. Drive 861.3 mi

    1. Drive from Jacksonville to St. Louiscar861.3 mi
    15h 5m
    $158–227

  5. Fly Orlando to Lambert–St. Louis International Airport

    1. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)planeMCO - STL
    5h 2m
    $165–415

  6. Fly Tampa to Lambert–St. Louis International Airport

    1. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)planeTPA - STL
    4h 58m
    $155–395

  7. Fly Miami International Airport to Lambert–St. Louis International Airport

    1. Fly from Miami International Airport (MIA) to Lambert–St. Louis International Airport (STL)planeMIA - STL
    4h 59m
    $293–603

  8. Fly Fort Lauderdale–Hollywood International Airport to Lambert–St. Louis International Airport

    1. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Lambert–St. Louis International Airport (STL)planeFLL - STL
    5h 7m
    $135–396

  9. Fly Ft. Myers to Lambert–St. Louis International Airport

    1. Fly from Ft. Myers (RSW) to Lambert–St. Louis International Airport (STL)planeRSW - STL
    6h 6m
    $166–858

  10. Bus via Dublin

    1. Take the bus from Jacksonville to Dublinbus
    2. Take the bus from Dublin to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus
    22h 18m
    $142–368

Florida to St. Louis by bus

Calendar14Weekly Buses
Duration18h 20mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

What companies run services between Florida, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and American Airlines fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Jacksonville to St Louis Bus Station via Atlanta Bus Station in around 18h 20m.

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