There are 6 ways to get from Florida to Key Largo by plane, shuttle, bus (Flixbus, Greyhound), train, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Orlando, shuttle
best- Fly from Orlando (MCO) to Miami International Airport (MIA)MCO - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
5h 4m$167–432Bus
cheapest- Take the bus from Jacksonville to Miami Airport StationFlixBus 2431
- Take the bus from Miami Airport Station to Key Largo Bus StopGreyhound US0720s
12h 58m$60–136Train, bus
- Take the train from Jacksonville to Miami Amtrak Station
- Take the bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ride38 / ...
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo301
14h 15mDrive 406 mi
- Drive from Jacksonville to Key Largo406 mi
6h 48m$75–107Fly from Tampa, shuttle
- Fly from Tampa (TPA) to Miami International Airport (MIA)TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
5h 4m$182–452Bus via Homestead
- Take the bus from Jacksonville to Downtown Miami
- Take the bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ride38 / ...
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo301
13h 54m
Florida to Key Largo by bus
Questions & Answers
The cheapest way to get from Florida to Key Largo is to drive which costs $70 - $110 and takes 6h 48m.
The fastest way to get from Florida to Key Largo is to fly and shuttle which takes 5h 4m and costs $160 - $440.
No, there is no direct bus from Florida to Key Largo. However, there are services departing from Newnan St + Ashley St and arriving at Key Largo Bus Stop via Jacksonville and Miami Airport Station. The journey, including transfers, takes approximately 12h 58m.
The distance between Florida and Key Largo is 264 miles. The road distance is 408.4 miles.
The best way to get from Florida to Key Largo without a car is to bus which takes 12h 58m and costs $60 - $140.
It takes approximately 5h 4m to get from Florida to Key Largo, including transfers.
Florida to Key Largo bus services, operated by Flixbus USA, depart from Jacksonville station.
Florida to Key Largo bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Florida to Key Largo is 408 miles. It takes approximately 6h 48m to drive from Florida to Key Largo.
There are 304+ hotels available in Key Largo.
What companies run services between Florida, USA and Key Largo, FL, USA?
You can take a bus from Newnan St + Ashley St to Key Largo Bus Stop via JRTC Bay J, Jacksonville, and Miami Airport Station in around 12h 58m.
- Website
- aa.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $30–210
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $30–240
- Website
- southwest.com
Flights from Orlando to Miami International Airport
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $30–210
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Miami Amtrak Station
- Ave. Duration
- 9h 10m
- Frequency
- Twice daily
- Estimated price
- $55–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 9h 15m
- Frequency
- Twice daily
- Estimated price
- $50–110
- Schedules at
- flixbus.com
Bus from Jacksonville to Downtown Miami
- Ave. Duration
- 9h 15m
- Frequency
- 5 times a week
- Estimated price
- $50–95
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jacksonville to Miami Airport Station
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $13–23
- Website
- https://www.greyhound.com/
- Phone
- +1 786-469-5675
- Website
- miamidade.gov
Bus from Dadeland South Metrorail Station to SW 344 St @ Park & Ride
- Ave. Duration
- 1h 12m
- Frequency
- Every 15 minutes
- Website
- https://www.miamidade.gov/global/transportation/home.page
Bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Website
- https://www.miamidade.gov/global/transportation/home.page
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide












