Rome2Rio

How to get fromFlorida to Iowaby plane, bus (Flixbus, Greyhound), train, bus, car or taxi

Find Transport to Iowa

See all options

There are 8 ways to get from Florida to Iowa by plane, bus (Flixbus, Greyhound), train, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando Sanford to Des Moines

    best
    1. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    3h 51m
    $168–554
  2. Fly Orlando to Des Moines

    cheapest
    1. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    5h 11m
    $94–403
  3. Bus

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    30h 57m
    $195–454
  4. Train, bus

    1. Take the train from Jacksonville to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    44h 28m
    $435–964
  5. Drive 1,191.5 mi

    1. Drive from Jacksonville to Des Moinescar car 1,191.5 mi
    21h 48m
    $218–315
  6. Taxi to Punta Gorda Airport, fly to Des Moines

    1. Take the taxi from Cape Coral to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Des Moines (DSM)plane plane PGD - DSM
    4h 7m
    $174–564
  7. Fly Orlando to Omaha

    1. Fly from Orlando (MCO) to Omaha (OMA)plane plane MCO - OMA
    5h 20m
    $237–1,132
  8. Fly Saint Petersburg–Clearwater International Airport to Des Moines

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Des Moines (DSM)plane plane PIE - DSM
    5h 39m
    $112–486

Orlando Sanford (SFB) to Des Moines (DSM) flights

Calendar8Weekly Planes
Duration3h 6mAverage Duration
Ticket$92Cheapest Price
See schedules

Questions & Answers

What companies run services between Florida, USA and Iowa, USA?

Allegiant Air flies from Orlando Sanford (SFB) to Des Moines (DSM) once daily. Alternatively, you can take a bus from Newnan St + Ashley St to Des Moines via JRTC Bay J, Jacksonville, Atlanta Bus Station, Chicago Bus Station, and Des Moines in around 30h 57m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound