There are 8 ways to get from Florida to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Tallahassee
best- Fly from Tallahassee (TLH) to Des Moines (DSM)plane TLH - DSM
5h 37m$291–1,449Bus
cheapest- Take the bus from Jacksonville to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
30h 52m$157–443Train, bus
- Take the train from Jacksonville to Chicago Union Stationtrain Floridian
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
44h 23m$252–913Drive 1,191.5 mi
- Drive from Jacksonville to Des Moinescar 1,191.5 mi
21h 48m$218–315Fly from Orlando Sanford
- Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane SFB - DSM
3h 53m$266–1,041Fly from Fort Lauderdale–Hollywood International Airport
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Des Moines (DSM)plane FLL - DSM
5h 20m$169–774Taxi to Punta Gorda Airport, fly
- Take the taxi from Cape Coral to Punta Gorda Airport (PGD)taxi
- Fly from Punta Gorda Airport (PGD) to Des Moines (DSM)plane PGD - DSM
4h 12m$269–1,094Fly from Miami International Airport
- Fly from Miami International Airport (MIA) to Des Moines (DSM)plane MIA - DSM
5h 23m$197–921
Florida to Des Moines by bus
Questions & Answers
The cheapest way to get from Florida to Des Moines is to drive which costs $210 - $320 and takes 21h 48m.
The fastest way to get from Florida to Des Moines is to fly which takes 3h 53m and costs $260 - $1,100.
No, there is no direct bus from Florida to Des Moines. However, there are services departing from Newnan St + Ashley St and arriving at Des Moines via Jacksonville, Atlanta Bus Station and Chicago Bus Station. The journey, including transfers, takes approximately 30h 52m.
The distance between Florida and Des Moines is 946 miles. The road distance is 1198.4 miles.
The best way to get from Florida to Des Moines without a car is to bus which takes 30h 52m and costs $150 - $450.
It takes approximately 5h 37m to get from Florida to Des Moines, including transfers.
Florida to Des Moines bus services, operated by Flixbus USA, depart from Jacksonville station.
The best way to get from Florida to Des Moines is to fly which takes 5h 37m and costs $290 - $1,500. Alternatively, you can bus, which costs $150 - $450 and takes 30h 52m.
Florida to Des Moines bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Des Moines is 1h behind Florida. It is currently 7:16 PM in Florida and 6:16 PM in Des Moines.
What companies run services between Florida, USA and Des Moines, IA, USA?
American Airlines and Delta fly from Tallahassee (TLH) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Newnan St + Ashley St to Des Moines via JRTC Bay J, Jacksonville, Atlanta Bus Station, and Chicago Bus Station in around 30h 52m.
- Website
- aa.com
Flights from Tallahassee to Des Moines via Charlotte
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $290–1,500
Flights from Tallahassee to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $320–1,600
Flights from Tallahassee to Des Moines via Reagan Washington
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $360–1,700
Flights from Fort Lauderdale–Hollywood International Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $160–800
Flights from Miami International Airport to Des Moines
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $180–900
- Website
- delta.com
Flights from Tallahassee to Des Moines via Atlanta
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Fort Lauderdale–Hollywood International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $150–750
Flights from Miami International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $190–900
- Website
- allegiantair.com
Flights from Orlando Sanford to Des Moines
- Ave. Duration
- 3h 7m
- When
- Monday, Friday, and Saturday
- Estimated price
- $190–950
Flights from Orlando Sanford to Des Moines via Austin
- Ave. Duration
- 6h 6m
- When
- Thursday
- Estimated price
- $260–1,200
Flights from Fort Lauderdale–Hollywood International Airport to Des Moines
- Ave. Duration
- 3h 40m
- When
- Thursday and Sunday
- Estimated price
- $150–750
Flights from Punta Gorda Airport to Des Moines
- Ave. Duration
- 3h 19m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $190–1,000
- Website
- southwest.com
Flights from Fort Lauderdale–Hollywood International Airport to Des Moines via St. Louis
- Ave. Duration
- 5h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Fort Lauderdale–Hollywood International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 6h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–800
Flights from Miami International Airport to Des Moines via St. Louis
- Ave. Duration
- 8h 20m
- When
- Saturday
- Estimated price
- $180–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jacksonville to Chicago Union Station
- Ave. Duration
- 35h 16m
- Frequency
- Once daily
- Estimated price
- $210–800
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 6h 40m
- Frequency
- 3 times a day
- Estimated price
- $45–120
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $80–190
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jacksonville to Atlanta Bus Station
- Ave. Duration
- 8h 45m
- Frequency
- Once daily
- Estimated price
- $40–130
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Chicago Bus Station
- Ave. Duration
- 16h
- Frequency
- 4 times a day
- Estimated price
- $75–200
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–110
- Website
- https://www.greyhound.com/
- Ave. Duration
- 41 min
- Estimated price
- $60–75
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
CT TAXI Transportation LLC
- Phone
- +1 239-218-9590
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More Questions & Answers
Yes, the driving distance between Florida to Des Moines is 1198 miles. It takes approximately 21h 48m to drive from Florida to Des Moines.
There are 221+ hotels available in Des Moines.






