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There are 4 ways to get from Florence to Cape Coral by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  6 h 37 min

  1. Fly from Florence (FLO) to Ft. Myers (RSW) FLO - RSW

$142 - $665

Cheapest option

Bus  •  18 h 12 min

  1. Take the bus from Florence, Sc to Orlando, Fl 1019
  2. Take the bus from Orlando, Fl to Ft Myers, Fl 3749

$75 - $184

2 alternative options

Train, bus  •  19 h 16 min

  1. Take the train from Florence Amtrak Station to West Palm Beach Amtrak Station Silver Meteor
  2. Take the bus from West Palm Beach, Fl to Ft Myers, Fl 3700

$117 - $321

Drive  •  10 h 36 min

  1. Drive from Florence to Cape Coral 633 miles

$60 - $90

Questions & Answers

The cheapest way to get from Florence to Cape Coral is to drive which costs $60 - $90 and takes 10 h 36 min.

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The quickest way to get from Florence to Cape Coral is to fly which costs $140 - $700 and takes 6 h 37 min.

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No, there is no direct bus from Florence to Cape Coral. However, there are services departing from Florence, Sc and arriving at Forty-Seventh Terrace @ Vincennes Boulevard via Orlando, Fl and Rosa Parks Transportation Center. The journey, including transfers, takes approximately 18 h 12 min.

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The distance between Florence and Cape Coral is 546 miles. The road distance is 633 miles.

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The best way to get from Florence to Cape Coral without a car is to bus which takes 18 h 12 min and costs $75 - $190.

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It takes approximately 6 h 37 min to get from Florence to Cape Coral, including transfers.

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Florence to Cape Coral bus services, operated by Greyhound USA, depart from Florence, Sc station.

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The best way to get from Florence to Cape Coral is to fly which takes 6 h 37 min and costs $140 - $700. Alternatively, you can bus, which costs $75 - $190 and takes 18 h 12 min.

Mode details

There is no direct flight from Florence Airport to Ft. Myers Airport. The quickest flight takes 3 h 55 min and has one stopover.

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Florence to Cape Coral bus services, operated by Greyhound USA, arrive at Ft Myers, Fl station.

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Map of how to get from Florence to Cape Coral.
Launch map view
  • Distance: 546.4 miles
  • Duration: 6 h 37 min

What companies run services between Florence, SC, USA and Cape Coral, FL, USA?

American Airlines flies from Florence to Cape Coral every 4 hours. Alternatively, you can take a bus from Florence to Cape Coral via Orlando, Fl, Ft Myers, Fl, and Rosa Parks Transportation Center in around 18 h 12 min.

Airlines
American Airlines
Website
aa.com
Flights from Florence to Ft. Myers via Charlotte
Ave. Duration
6 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $650
Flights from Florence to Ft. Myers via Charlotte, Philadelphia
Ave. Duration
7 h 59 min
When
Monday, Wednesday, Thursday and Friday
Estimated price
$170 - $700
Flights from Florence to Ft. Myers via Charlotte, Dallas/Ft.Worth
Ave. Duration
8 h 38 min
When
Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$200 - $750
Flights from Florence to Ft. Myers via Charlotte, Reagan Washington
Ave. Duration
8 h 44 min
When
Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $700
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Florence Amtrak Station to West Palm Beach Amtrak Station
Ave. Duration
13 h 34 min
Frequency
Once daily
Estimated price
$95 - $280
Website
amtrak.com
Coach Seat
$95 - $150
Flexi Coach Seat
$170 - $250
Business Coach Seat
$190 - $280
Room
$400 - $550
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Florence, Sc to Orlando, Fl
Ave. Duration
9 h 30 min
Frequency
5 times a day
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $80
Flexible
$90 - $120
Bus from Orlando, Fl to Ft Myers, Fl
Ave. Duration
6 h 5 min
Frequency
3 times a day
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from West Palm Beach, Fl to Ft Myers, Fl
Ave. Duration
3 h 5 min
Frequency
3 times a day
Estimated price
$18 - $45
Website
greyhound.com
Economy
$18 - $28
Flexible
$30 - $45

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Florence to Cape Coral is 633 miles. It takes approximately 10 h 36 min to drive from Florence to Cape Coral.

Get driving directions

American Airlines offers flights from Florence Airport to Ft. Myers Airport.

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There are 1564+ hotels available in Cape Coral. Prices start at $81 USD per night.

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The best way to get from Florence to Florence Airport is to taxi which takes 4 min and costs $8 - $11.

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