There are 9 ways to get from Florence to Cape Cod by bus, plane, train, bus (Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Myrtle Beach, fly to Boston Logan Airport, bus
best- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to Boston Logan Airport (BOS)plane MYR - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
8h 54m$114–353Train, bus
- Take the train from Florence Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the bus from Boston South Station to Barnstablebus
19h 23m$191–1,015Bus
- Take the bus from Florence, SC to New York, NYbus
- Take the bus from New York City Chinatown to Bostonbus
- Take the bus from Boston South Station to Hyannis Transportation Centerbus
21h 53m$133–230Drive 868.2 mi
- Drive from Florence to Cape Codcar 868.2 mi
15h 50m$159–229Bus to Charlotte Douglas International Airport, fly to Boston Logan Airport, bus
- Take the bus from Florence Bus Station to Charlotte Bus Stationbus
- Fly from Charlotte Douglas International Airport (CLT) to Boston Logan Airport (BOS)plane CLT - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
10h 54m$158–429Train to Charleston International Airport, fly to Boston Logan Airport, bus
- Take the train from Florence Station to Charleston Amtrak Stationtrain
- Fly from Charleston International Airport (CHS) to Boston Logan Airport (BOS)plane CHS - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
10h 48m$187–494Bus to Myrtle Beach, fly to Theodore Francis Green State Airport, train, bus
- Take the bus from Florence Bus Station to Myrtle Beach Bus Stationbus
- Fly from Myrtle Beach (MYR) to Theodore Francis Green State Airport (PVD)plane MYR - PVD
- Take the train from TF Green Airport to South Stationtrain
- Take the bus from Boston South Station to Hyannis Transportation Centerbus
11h 17m$242–639Train, bus to Wilmington International Airport, fly to Boston Logan Airport, bus
- Take the train from Florence Station to Fayetteville Amtrak Stationtrain
- Take the bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transitbus
- Fly from Wilmington International Airport (ILM) to Boston Logan Airport (BOS)plane ILM - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
12h 2m$230–721Bus via Raleigh
- Take the bus from Florence Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Peter Pan Bus Terminalbus
- Take the bus from Providence Bus Terminal to Hyannis Transportation Centerbus
22h 53m$125–241
Florence to Cape Cod by bus
Questions & Answers
The cheapest way to get from Florence to Cape Cod is to bus via Raleigh which costs $120 - $250 and takes 22h 53m.
The fastest way to get from Florence to Cape Cod is to bus and fly which takes 8h 54m and costs $110 - $360.
No, there is no direct bus from Florence to Cape Cod. However, there are services departing from Florence, SC and arriving at Town Hall Lawton Bus Shelter via New York City Chinatown, Boston South Station and Hyannis Transportation Center. The journey, including transfers, takes approximately 21h 53m.
The distance between Florence and Cape Cod is 897 miles. The road distance is 873.3 miles.
The best way to get from Florence to Cape Cod without a car is to train and bus which takes 19h 23m and costs $190 - $1,100.
It takes approximately 8h 54m to get from Florence to Cape Cod, including transfers.
Florence to Cape Cod bus services, operated by Wanda Coach, depart from Florence, SC station.
Florence to Cape Cod bus services, operated by Wanda Coach, arrive at New York, NY station.
Yes, the driving distance between Florence to Cape Cod is 873 miles. It takes approximately 15h 50m to drive from Florence to Cape Cod.
There are 865+ hotels available in Cape Cod.
What companies run services between Florence, SC, USA and Cape Cod, MA, USA?
You can take a bus from Florence, SC to Town Hall Lawton Bus Shelter via New York, NY, New York City Chinatown, Boston, Boston South Station, and Hyannis Transportation Center in around 21h 53m.
- Website
- aa.com
Flights from Myrtle Beach to Boston Logan Airport
- Ave. Duration
- 2h 10m
- When
- Sunday
- Estimated price
- $80–450
Flights from Myrtle Beach to Boston Logan Airport via Philadelphia
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $85–450
Flights from Myrtle Beach to Boston Logan Airport via Reagan Washington
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $85–460
Flights from Charlotte Douglas International Airport to Boston Logan Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $75–430
Flights from Charlotte Douglas International Airport to Boston Logan Airport via Reagan Washington
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $75–430
Flights from Charleston International Airport to Boston Logan Airport via Reagan Washington
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $90–490
Flights from Myrtle Beach to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 3h 47m
- When
- Friday
- Estimated price
- $50–300
Flights from Myrtle Beach to Theodore Francis Green State Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 21m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $55–310
Flights from Myrtle Beach to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $50–290
Flights from Wilmington International Airport to Boston Logan Airport
- Ave. Duration
- 2h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–440
Flights from Wilmington International Airport to Boston Logan Airport via Philadelphia
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $80–450
Flights from Wilmington International Airport to Boston Logan Airport via Reagan Washington
- Ave. Duration
- 4h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–450
Flights from Wilmington International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 4h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–440
- Website
- delta.com
Flights from Myrtle Beach to Boston Logan Airport
- Ave. Duration
- 2h 14m
- When
- Thursday and Friday
- Estimated price
- $80–450
Flights from Myrtle Beach to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 4h 5m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–450
Flights from Charlotte Douglas International Airport to Boston Logan Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $75–430
Flights from Charleston International Airport to Boston Logan Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $90–480
Flights from Wilmington International Airport to Boston Logan Airport
- Ave. Duration
- 2h 24m
- When
- Saturday
- Estimated price
- $80–440
Flights from Wilmington International Airport to Boston Logan Airport via New York La Guardia
- Ave. Duration
- 4h 22m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–440
- Website
- southwest.com
Flights from Myrtle Beach to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h 12m
- When
- Saturday
- Estimated price
- $85–460
Flights from Charleston International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h 23m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $90–490
Flights from Myrtle Beach to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $50–290
- Website
- united.com
Flights from Charleston International Airport to Boston Logan Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $95–490
Flights from Charleston International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 4h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–480
Flights from Wilmington International Airport to Boston Logan Airport via Newark
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $80–440
- Website
- spirit.com
Flights from Myrtle Beach to Boston Logan Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $60–280
Flights from Charlotte Douglas International Airport to Boston Logan Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $100–350
- Website
- jetblue.com
Flights from Charleston International Airport to Boston Logan Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $90–480
Flights from Wilmington International Airport to Boston Logan Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $80–440
- Website
- flybreeze.com
Flights from Myrtle Beach to Theodore Francis Green State Airport
- Ave. Duration
- 1h 57m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $200–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Florence Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 12h 30m
- Frequency
- Twice daily
- Estimated price
- $110–170
- Website
- https://www.amtrak.com/home.html
Train from Florence Station to Charleston Amtrak Station
- Ave. Duration
- 1h 33m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- https://www.amtrak.com/home.html
Train from Florence Station to Fayetteville Amtrak Station
- Ave. Duration
- 1h 21m
- Frequency
- Twice daily
- Estimated price
- $25–45
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from TF Green Airport to South Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $6–16
- Website
- https://www.mbta.com
- Adult
- $6–16
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Florence Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–17
- Website
- https://www.greyhound.com/
Bus from Fayetteville Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Florence Bus Station to Raleigh Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 9h 50m
- Frequency
- Every 4 hours
- Estimated price
- $60–110
- Website
- https://www.greyhound.com/
- Phone
- +1 (508) 746-0378
- info@p-b.com
- Website
- p-b.com
Bus from Logan International Airport to Hyannis Transportation Center
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- $28–40
- Website
- https://www.p-b.com
- One Way - Adult
- $28–40
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Boston South Station to Barnstable
- Ave. Duration
- 1h 15m
- Frequency
- Every 3 hours
- Estimated price
- $9–40
- Website
- https://peterpanbus.com
- Adult
- $9–40
Bus from Boston South Station to Hyannis Transportation Center
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Estimated price
- $10–40
- Website
- https://peterpanbus.com
- Adult
- $10–40
Bus from Port Authority Bus Terminal to Peter Pan Bus Terminal
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $25–55
- Website
- https://peterpanbus.com
- Adult
- $25–55
Bus from Providence Bus Terminal to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- $11–40
- Website
- https://peterpanbus.com
- Adult
- $11–40
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Florence, SC to New York, NY
- Ave. Duration
- 12h
- Frequency
- 3 times a day
- Estimated price
- $90–130
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York City Chinatown to Boston
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–65
- Schedules at
- flixbus.com
Bus from Florence Bus Station to Charlotte Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $23–30
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide

















