There are 11 ways to get from Florence to Mainz by plane, train (Trenitalia), train, bus, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Florence Peretola Airport
best- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)plane FLR - FRA
4h 30m€104–305Bus
cheapest- Take the bus from Florence Villa Constanza Bus Station to Frankfurt central train stationbus N77 / ...
19h 10m€67–114Train
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
11h 22m€163–284Train, bus
- Take the train from Firenze Santa Maria Novella to Milano Rogoredotrain 9904 / ...
- Take the bus from Milano, Autostazione Lampugnano to Frankfurt - Airport Bus Stationbus BlaBlaCar Bus
15h 33m€104–148Drive 958.5 km
- Drive from Florence to Mainzcar 958.5 km
9h 2m€147–212Train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Florence Santa Maria Novella to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)plane BLQ - FRA
4h 58m€136–309Train to Verona Villafranca Airport, fly
- Take the train from Firenze S.M.N. to Verona Porta Nuovatrain
- Fly from Verona Villafranca Airport (VRN) to Frankfurt (FRA)plane VRN - FRA
5h 58m€143–376Train to Venice Marco Polo Airport, fly
- Take the train from Firenze S.M.N. to Venezia Mestretrain
- Fly from Venice Marco Polo Airport (VCE) to Frankfurt (FRA)plane VCE - FRA
6h 28m€128–345Train to Milan Linate Airport, fly
- Take the train from Florence Santa Maria Novella to Milan Rogoredotrain
- Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane LIN - FRA
6h 2m€92–210Train #2
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
11h 22m€182–263Drive, car train
- Drive from Florence to München Ostcar
- Take the car train from München Ost to Würzburg Hbfcartrain
- Drive from Würzburg Hbf to Mainzcar
9h 17m€204–276
Florence to Mainz by train
Questions & Answers
The cheapest way to get from Florence to Mainz is to bus which costs €65 - €120 and takes 19h 10m.
The fastest way to get from Florence to Mainz is to fly which takes 4h 30m and costs €100 - €310.
No, there is no direct bus from Florence station to Mainz station. However, there are services departing from Florence Villa Constanza Bus Station and arriving at Mainz central train station via Frankfurt central train station. The journey, including transfers, takes approximately 19h 10m.
No, there is no direct train from Florence to Mainz. However, there are services departing from Firenze S.M.N. and arriving at Mainz, Römisches Theater via Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 11h 22m.
The distance between Florence and Mainz is 754 km. The road distance is 958.5 km.
The best way to get from Florence to Mainz without a car is to train which takes 11h 22m and costs €160 - €290.
It takes approximately 4h 30m to get from Florence to Mainz, including transfers.
Florence to Mainz bus services, operated by FlixBus, depart from Florence Villa Constanza Bus Station.
Florence to Mainz train services, operated by Trenitalia Frecce, depart from Firenze S.M.N. station.
The best way to get from Florence to Mainz is to fly which takes 4h 30m and costs €100 - €310. Alternatively, you can train, which costs €160 - €290 and takes 11h 22m, you could also bus, which costs €65 - €120 and takes 19h 10m.
What companies run services between Florence, Italy and Mainz, Germany?
Air Dolomiti, Lufthansa, and Swiss fly from Florence Peretola Airport (FLR) to Frankfurt (FRA) every 4 hours. Alternatively, you can take a train from Firenze S.M.N. to Mainz, Römisches Theater via Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 11h 22m.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €95–360
Flights from Florence Peretola Airport to Frankfurt via Munich
- Ave. Duration
- 3h 37m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €110–360
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €90–340
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €90–340
Flights from Verona Villafranca Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €90–310
Flights from Verona Villafranca Airport to Frankfurt via Munich
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €90–310
Flights from Venice Marco Polo Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €90–280
Flights from Venice Marco Polo Airport to Frankfurt via Munich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €80–310
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–230
Flights from Milan Linate Airport to Frankfurt via Munich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €60–230
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €110–360
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €90–340
Flights from Verona Villafranca Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €90–310
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €60–230
- Website
- swiss.com
Flights from Florence Peretola Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €120–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–270
Flights from Venice Marco Polo Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €120–200
- Website
- easyjet.com
Flights from Milan Linate Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–130
- Website
- condor.com
Flights from Venice Marco Polo Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €55–250
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–85
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Verona Porta Nuova
- Ave. Duration
- 1h 32m
- Frequency
- Every 4 hours
- Estimated price
- €29–60
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Venezia Mestre
- Ave. Duration
- 2h 3m
- Frequency
- Hourly
- Estimated price
- €35–70
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze Santa Maria Novella to Milano Rogoredo
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- €50–65
- Website
- https://www.italotreno.it/en
- Smart Economy
- €50–65
- Smart Flex
- €50–65
Train from Florence Santa Maria Novella to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Hourly
- Estimated price
- €28–40
- Website
- https://www.italotreno.it/en
- Smart Economy
- €28–40
- Smart Flex
- €29–40
Train from Florence Santa Maria Novella to Milan Rogoredo
- Ave. Duration
- 1h 43m
- Frequency
- Every 3 hours
- Estimated price
- €45–65
- Website
- https://www.italotreno.it/en
- Smart Economy
- €45–60
- Smart Flex
- €50–65
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €45–65
- Website
- https://www.italotreno.it/en
- Smart Economy
- €45–65
- Smart Flex
- €50–65
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from München Ost to Würzburg Hbf
- Ave. Duration
- 1h 37m
- Frequency
- Once daily
- Estimated price
- €90–110
- Website
- https://urlaubs-express.de/?lang=en
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Milano, Autostazione Lampugnano to Frankfurt - Airport Bus Station
- Ave. Duration
- 11h 50m
- Frequency
- 3 times a week
- Estimated price
- €45–70
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Florence Villa Constanza Bus Station to Frankfurt central train station
- Ave. Duration
- 17h 30m
- Frequency
- Twice daily
- Estimated price
- €65–110
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Florence to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Florence to Mainz train services, operated by Trenitalia Frecce, arrive at Milano Centrale station.
Yes, the driving distance between Florence to Mainz is 958 km. It takes approximately 9h 2m to drive from Florence to Mainz.
Book your Florence to Mainz bus tickets online with FlixBus.
There are 1155+ hotels available in Mainz.




































